Results 101 to 110 of about 114,054,514 (226)

Sperm Telomere Interactions Are Impaired in Testicular Cancer Before and After Adjuvant Therapy

open access: yesAndrology, EarlyView.
ABSTRACT Background No study has yet explored telomere length or interaction in sperm nuclei of testicular cancer (TC) patients exposed to chemotherapy or radiotherapy. However, sperm telomere dynamics have emerged as a potential marker in male infertility.
Benoit Berby   +10 more
wiley   +1 more source

Zebrafish dmrta2 Regulates the Expression of cdkn2c in Spermatogenesis in the Adult Testis

open access: yes, 2013
The exact function of the doublesex and mab-3 related transcription factor-like family a2 gene (dmrta2) has remained largely unknown possibly because of its functional redundancy with dmrta1 in most vertebrates.
Xia, Wei   +4 more
core   +1 more source

Biology and manipulation technologies of male germline stem cells in mammals

open access: yesReproductive Medicine and Biology, 2018
Background Spermatogonial stem cells (SSCs) are the origin of sperm and defined by their functions of “colonization in the testis” and “spermatogenesis”.
Seiji Takashima
doaj   +1 more source

Seminal Plasma Exosomal miRNA Profiling Reveals hsa‐miR‐7‐5p as a Key Regulator of Sperm Motility in Asthenozoospermia

open access: yesAndrology, EarlyView.
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu   +8 more
wiley   +1 more source

ROLE OF THE ENDOCANNABINOID SYSTEM IN SPERMATOGENESIS: SYSTEMS BIOLOGY APPROACH

open access: yes, 2014
The spermatogenesis is a complex process that requires the differentiation of male gametes within the male genital tract. It involves a series of cellular events including mitosis, meiosis, cell migration, apoptosis, and differentiation of diploid germ
BARBONI, Barbara   +4 more
core   +1 more source

Inhibition of HMGA2 Leads to Reduced Cell Proliferation and Increased Apoptosis in Human Embryonal Carcinoma Cell Lines

open access: yesAndrology, EarlyView.
ABSTRACT Background The most prevalent solid tumors in young men are testicular germ cell tumors (TGCTs), and embryonal carcinoma is the most common subtype among non‐seminomatous germ cell tumors (NSGCTs). Despite the excellent cure rates of cisplatin‐based chemotherapy, resistance develops in 15%–30% of patients with metastatic cancer, which results ...
Marco De Martino   +5 more
wiley   +1 more source

Ubiquitous Flame-Retardant Toxicants Impair Spermatogenesis in a Human Stem Cell Model

open access: yesiScience, 2018
Summary: Sperm counts have rapidly declined in Western males over the past four decades. This rapid decline remains largely unexplained, but exposure to environmental toxicants provides one potential explanation for this decline.
Alyse N. Steves   +9 more
doaj   +1 more source

In vitro Spermatogenesis of Gypsy Moth Larvae

open access: yesThe American Biology Teacher, 1994
This laboratory activity is designed to offer students an opportunity to establish simple cell developmental cultures in order to observe the process of spermatogenesis, mitosis and meiosis in living cells. Insect cultures grow at room temperature and do not require a special incubator or complex growth media.
Judy Brown, Marcia J. Loeb
openaire   +1 more source

T Cell Microenvironmental Impacts and Therapeutic Opportunities: Application to Human Testicular Germ Cell Tumors

open access: yesAndrology, EarlyView.
ABSTRACT Testicular germ cell tumors (TGCT) are the leading malignancy in adolescent and young adult males, yet the immunological and cellular mechanisms governing their tumor microenvironment (TME) remain poorly understood. Here, we present a comprehensive review of TGCT pathobiology with a focus on the immune landscape, particularly the role of tumor‐
R Islam   +7 more
wiley   +1 more source

Physical environment in non-ventilated culture vessels affects in vitro growth and morphogenesis of several cultivars of Dianthus Caryophyllus L. [PDF]

open access: yes, 2002
Differences were shown in the environmental conditions inside four types of non-ventilated culture vessels (glass baby-food jars capped with metal steel or Magenta B-caps, jam glass jars capped with metal steel caps, and Magenta GA7 culture vessels) that
Fall, M. A.   +2 more
core  

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