Results 111 to 120 of about 51,909 (235)

The use of deidentified organ donor testes for research

Andrology, EarlyView.
Abstract Our knowledge of testis development and function mainly comes from research using mammalian model organisms, primarily the mouse. However, there are integral differences between men and other mammalian species regarding cellular composition and expression profiles during fetal and post‐natal testis development and in the mature testis ...
Marina V. Pryzhkova, Marnie W. Skinner, Juliana I. Candelaria, Stephen R. Wellard, Philip W. Jordan   +4 more
wiley   +1 more source

Establishment of a Southern catfish (Silurus meridionalis) spermatogonial stem cell line capable of sperm production in vitro

Aquaculture Reports
Southern catfish (Silurus meridionalis) is widely distributed in the Yangtze River and its tributaries and is valued for its rapid growth, nutritional content, pleasant taste, absence of intermuscular bone, and disease resistance.
Jianeng Li, Changle Zhao, Lei Liu, Shuqing Zheng, Deshou Wang, Changwei Shao, Jing Wei   +6 more
doaj   +1 more source

BRD9 inhibition as potential treatment option for testicular germ cell tumors

Andrology, EarlyView.
Abstract Background Testicular germ cell tumors (TGCT) are the predominant tumor in younger males. Usually, 5‐year survival rates are quite high, but 15–20% of patients with metastatic non‐seminomas are resistant to standard cisplatin‐based therapy.
Aylin Hansen, Christine Sanders, Florian Fronhoffs, Kai Funke, Glen Kristiansen, Hubert Schorle   +5 more
wiley   +1 more source

Distinct roles of melatonin receptors in spermatogenesis in vitro in four-eyed sleeper (Bostrychus sinensis)

Aquaculture Reports
Melatonin is a master neuroendocrine hormone in regulation of circadian rhythm and seasonal breeding behaviors in animal kingdom. Recently, we used the scaffold material to establish the three-dimension (3D) culture method, by which we found that ...
Jiajun Yao, Haifeng Li, Han Yang, Meisheng Yi, Wei Liu   +4 more
doaj   +1 more source

The role of iron in normal and impaired testicular function

Andrology, EarlyView.
Abstract Iron plays a critical role in testicular physiology, impacting spermatogenesis, testosterone production, and overall testicular function. Iron homeostasis is maintained through systemic and cellular regulatory mechanisms, including hepcidin‐mediated systemic iron control and the iron‐responsive element/iron regulatory protein (IRE/IRP) system ...
Aileen Harrer, Esther G. Meyron‐Holtz, Andreas Meinhardt   +2 more
wiley   +1 more source

Cryptorchidism: Novel genetic insights into CCDC149 mutations

Andrology, EarlyView.
Abstract Background Cryptorchidism, characterized by the failure of one or both testes to descend into the scrotum, is a common congenital condition that can lead to infertility and increased risk of testicular cancer. CCDC149, a coiled‐coil domain‐containing protein, has been implicated in various developmental processes, but its role in the male ...
Shengrong Du, Shan Xu, Lei Yang, Yan Ye, Yuhan Wu, Ziyun Xiao, Xiuqing Dong, Wenliang Yao, Hua Li   +8 more
wiley   +1 more source

Biology and manipulation technologies of male germline stem cells in mammals

Reproductive Medicine and Biology, 2018
Background Spermatogonial stem cells (SSCs) are the origin of sperm and defined by their functions of “colonization in the testis” and “spermatogenesis”.
Seiji Takashima
doaj   +1 more source

Evidence suggesting that di-n-butyl phthalate has anti-androgenic effects in fish [PDF]

, 2011
This article is the pre-print version of the full and final published article.Phthalate ester plasticizers are anti-androgenic in mammals. High doses of certain phthalates consistently interfere with the normal development of male offspring exposed in ...
Adams, Akingbemi, Autian, Bjorkblom, Borch, Culty, Dargnat, Filby, Foster, Fromme, Graham, Gray, Han, Harries, Horn, Jobling, Jobling, Jobling, Jolly, Katsiadaki, Katsiadaki, Kim, Lee, Lehmann, Liu, Loraine, Mackintosh, McCurley, Moore, Ogunfowokan, Pfaffl, Schettler, Scott, Scott, Sebire, Shen, Staples, Uren-Webster, Vethaak, Villeneuve   +39 more
core   +1 more source

CRISPR/Cas9‐mediated Genome‐editing Reveals 10 Testis‐enriched Genes and One Non‐testis‐enriched Gene are Dispensable for Male Fecundity in Mice

Andrology, EarlyView.
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu, Keisuke Shimada, Masahito Ikawa   +2 more
wiley   +1 more source

Interphase chromosome positioning in in vitro porcine cells and ex vivo porcine tissues [PDF]

, 2012
Copyright @ 2012 The Authors. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and 85 reproduction in any medium, provided the original author and source
A Bolzer, A Fiebig, BM Skinner, C Federico, CK Lee, D Koehler, Darren K Griffin, DJ Prockop, FA Habermann, FH Gage, G Rettenberger, GA Rohrer, GM Cooper, H Ellegren, H Tanabe, H Tanabe, H Telenius, H Telenius, HA Foster, HA Foster, HA McQueen, HB Sun, Helen A Foster, I Szczerbal, IS Mehta, IS Mehta, J Ferreira, JA Croft, JM Bridger, JM Bridger, JM Craig, JM Craig, Joanna M Bridger, KJ Meaburn, KJ Meaburn, KJ Meaburn, L Mora, L Parada, L Schook, LA Parada, M Cremer, M Cremer, M Ferrari, M Knight, M Kuroda, M Neusser, M Yerle-Bouissou, N Gilbert, O Alexandrova, R Mayer, S Boyle, T Cremer, T Cremer, T Misteli, WA Bickmore, Z Jiang   +55 more
core   +2 more sources