Results 61 to 70 of about 652,351 (312)

Metabolomic profiling of plasma reveals differential disease severity markers in avian influenza A(H7N9) infection patients

International Journal of Infectious Diseases
Objectives: Avian influenza such as H7N9 is currently a major global public health risk, and at present, there is a lack of relevant diagnostic and treatment markers. Methods: We collected plasma samples from 104 confirmed H7N9 patients, 31 of whom died.
Yuefeng Wang, Jili Ni, Mingzhu Huang, Wenxin Qu, Chang Liu, Zheying Mao, Jiaqi Bao, Weizhen Chen, Dongsheng Han, Fei Yu, Yifei Shen, Zhenzhen Deng, Shufa Zheng   +12 more
doaj   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

In vitro immunological techniques in fascioliasis

, 1975
Experiments were conducted to examine ways of monitoring immunological responses in sheep to infection with Fasciola hepatica. The enzyme- linked immunosorbent assay (ELISA), the radioimmunoassay, and the agar gel precipitin technique were evaluated using the same somatic fluke antigen, for sensitivity and accuracy in the serodiagnosis of fascioliasis ...
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

FEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman, Annika Egeler, Saskia Rödl, Johannes M. Herrmann   +3 more
wiley   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Effect of hydroalcoholic extracts of flower and fruit peel of Punica granatum on Leishmania major promastigotes in vitro [PDF]

Advanced Herbal Medicine, 2020
Background and aims: Cutaneous leishmaniasis is one of the endemic parasitic diseases in many regions of Iran for which there is currently no complete vaccine and effective drugs without drug resistance to prevent and treat it.
Hamidreza Mardani, Bahman Khalili, Sedigheh Saberi, Zahra Lorigooini, Milad Ghaderi, Rahman Abdizadeh   +5 more
doaj  

Effectiveness of in vitro maturation and in vitro fertilization techniques in pigs [PDF]

Bioscientifica Proceedings, 2020
In vitro maturation and in vitro fertilization techniques in pigs have progressed considerably in recent years. Many reports focus on the factors affecting in vitro maturation that lead to normal male pronuclear formation or monospermy after fertilization in vitro.
openaire   +3 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Is Novamin Toothpaste Effective on Enamel Remineralization? An In-Vitro Study

Cumhuriyet Dental Journal, 2019
Objectives: New bio-active glass containing toothpaste (NovaMin) is one of the most effective cariostatic products when used as a daily application the aim of this in-vitro study is to evaluate the influence of NovaMin on enamel remineralization ...
Damla Aksit Bıçak, Dilara Ozenay Dergin, Didem Kural, İlknur Tanboğa, Zerrin Abbasoglu   +4 more
doaj   +1 more source