Results 61 to 70 of about 1,276,228 (308)

Axisymmetric polydimethysiloxane microchannels for in vitro hemodynamic studies [PDF]

, 2009
The current microdevices used for biomedical research are often manufactured using microelectromechanical systems (MEMS) technology. Although it is possible to fabricate precise and reproducible rectangular microchannels using soft lithography techniques,
Ishikawa, T., Kaji, H., Lima, Rui, Nishizawa, M., Oliveira, Monica, Tanaka, S., Yamaguchi, T.   +6 more
core   +1 more source

In Vitro Techniques for the Assessment of Neurotoxicity

Environmental Health Perspectives, 1998
Risk assessment is a process often divided into the following steps: a) hazard identification, b) dose-response assessment, c) exposure assessment, and d) risk characterization. Regulatory toxicity studies usually are aimed at providing data for the first two steps.
G. J. Harry, M. Billingsley, A. Bruinink, I. L. Campbell, W. Classen, D. C. Dorman, C.L. Galli, D. Ray, R. A. Smith, H. A. Tilson   +9 more
openaire   +3 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

In vitro meat production: Challenges and benefits over conventional meat production

Journal of Integrative Agriculture, 2015
In vitro meat production system is the production of meat outside the food animals by culturing the stem cells derived from farm animals inside the bioreactor by using advanced tissue engineering techniques.
Zuhaib Fayaz Bhat, Sunil Kumar, Hina Fayaz   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

International multicenter development of ensemble machine learning driven host response based diagnosis for tuberculosis

iScience
Summary: Active pulmonary tuberculosis (TB) is challenging to diagnose, and monitoring treatment response effectively remains difficult. To address these challenges, we developed TB-Scope, a host-gene-expression-based ensemble machine learning ...
Shufa Zheng, Wenxin Qu, Dan Zhang, Jieting Zhou, Yifan Xu, Wei Wu, Chang Liu, Mingzhu Huang, Enhui Shen, Xiao Chen, Michael P. Timko, Longjiang Fan, Fei Yu, Dongsheng Han, Yifei Shen   +14 more
doaj   +1 more source

Performance of progressive and constant tapered instruments rotary systems at canal preparation

RGO: Revista Gaúcha de Odontologia, 2018
Objective: The aim of this study was to compare the performance of two nickel-titanium rotary systems regarding the preparation time, final shape of canal, incidence of aberration, transportation, and fracture of instrument.
Bruna GENARI, Ruggiero Silveira STELLO, Fabiana Soares GRECCA, Susana Maria Werner SAMUEL , Fabrício Mezzomo COLLARES , Paul Michael Howell DUMMER   +5 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

BiodentineTM is cytocompatible with human primary osteoblasts

Brazilian Oral Research, 2017
Calcium silicate-based materials have been widely studied due to their resemblance to, and similar applicability of, mineral trioxide aggregate (MTA).
Miriam Zaccaro SCELZA, Joyce Costa NASCIMENTO, Licinio Esmeraldo da SILVA, Vinícius Shott GAMEIRO, Gustavo DE DEUS, Gutemberg ALVES   +5 more
doaj   +1 more source

Component-Resolved in Vitro Diagnosis in Peach-Allergic Patients [PDF]

, 2009
BACKGROUND: The in vitro diagnosis of pollen-related food allergy presents low specifi city and reproducibility with many conventional extracts. This can be improved using natural purifi ed allergens, recombinant purifi ed allergens, or both.
Antepara, I., Barber, Domingo, Ferrer, M., Gamboa, P.M., Goikoetxea, M.J., Lombardero, M., Salcedo Duran, Gabriel, Sanz, M.L., Sánchez-Monge Laguna de Rins, Rosa   +8 more
core   +1 more source