Results 21 to 30 of about 3,388,289 (318)

Timely coupling of sleep spindles and slow waves linked to early amyloid-β burden and predicts memory decline

eLife, 2022
Sleep alteration is a hallmark of ageing and emerges as a risk factor for Alzheimer’s disease (AD). While the fine-tuned coalescence of sleep microstructure elements may influence age-related cognitive trajectories, its association with AD processes is ...
Daphne Chylinski, Maxime Van Egroo, Justinas Narbutas, Vincenzo Muto, Mohamed Ali Bahri, Christian Berthomier, Eric Salmon, Christine Bastin, Christophe Phillips, Fabienne Collette, Pierre Maquet, Julie Carrier, Jean-Marc Lina, Gilles Vandewalle   +13 more
doaj   +1 more source

Dopamine Neuron Challenge Test for early detection of Parkinson’s disease

npj Parkinson's Disease, 2021
Diagnosing Parkinson’s disease (PD) before the clinical onset proves difficult because the hallmark PD symptoms do not manifest until more than 60% of dopamine neurons in the substantia nigra pars compacta have been lost.
Jingheng Zhou, Jicheng Li, Amy B. Papaneri, Nicholas P. Kobzar, Guohong Cui   +4 more
doaj   +1 more source

Positive Effect of Cognitive Reserve on Episodic Memory, Executive and Attentional Functions Taking Into Account Amyloid-Beta, Tau, and Apolipoprotein E Status

Frontiers in Aging Neuroscience, 2021
Studies exploring the simultaneous influence of several physiological and environmental factors on domain-specific cognition in late middle-age remain scarce.
Justinas Narbutas, Justinas Narbutas, Daphne Chylinski, Maxime Van Egroo, Mohamed Ali Bahri, Ekaterina Koshmanova, Gabriel Besson, Vincenzo Muto, Christina Schmidt, Christina Schmidt, André Luxen, Evelyne Balteau, Christophe Phillips, Pierre Maquet, Pierre Maquet, Eric Salmon, Eric Salmon, Eric Salmon, Gilles Vandewalle, Christine Bastin, Christine Bastin, Fabienne Collette, Fabienne Collette   +22 more
doaj   +1 more source

Biological Applications of Electron Paramagnetic Resonance Viscometry Using a ¹³C-Labeled Trityl Spin Probe

Molecules, 2021
Alterations in viscosity of biological fluids and tissues play an important role in health and diseases. It has been demonstrated that the electron paramagnetic resonance (EPR) spectrum of a 13C-labeled trityl spin probe (13C-dFT) is highly sensitive to ...
Murugesan Velayutham, Martin Poncelet, Timothy D. Eubank, Benoit Driesschaert, Valery V. Khramtsov   +4 more
doaj   +1 more source

Persistent Quantitative Vitality of Stem Cell Graft Is Necessary for Stabilization of Functional Brain Networks After Stroke

Frontiers in Neurology, 2019
Stem cell treatment after stroke has demonstrated substantial outcome improvement. However, monitoring of stem cell fate in vivo is still challenging and not routinely performed, yet important to quantify the role of the implanted stem cells on lesion ...
Claudia Green, Anuka Minassian, Stefanie Vogel, Michael Diedenhofen, Dirk Wiedermann, Mathias Hoehn, Mathias Hoehn, Mathias Hoehn   +7 more
doaj   +1 more source

CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma

OncoImmunology, 2021
Multiple myeloma (MM) is a hematological malignancy characterized by the presence of clonal plasma cells in the bone marrow niche. Despite significant therapeutic advances, MM remains incurable for the majority of patients. Targeted radionuclide therapy (
Kim De Veirman, Janik Puttemans, Ahmet Krasniqi, Thomas Ertveldt, Heleen Hanssens, Ema Romao, Dirk Hose, Cleo Goyvaert, Philip Vlummens, Serge Muyldermans, Karine Breckpot, Frank Bruchertseifer, Alfred Morgenstern, Matthias D’Huyvetter, Nick Devoogdt   +14 more
doaj   +1 more source

Development of a sensitive ELISA to quantify apolipoprotein CIII in nonhuman primate serum

Journal of Lipid Research, 2011
Apolipoprotein CIII (apoCIII), a major constituent of triglyceride-rich lipoprotein, has been proposed as a key contributor to hypertriglyceridemia on the basis of its inhibitory effects on lipoprotein lipase.
Yuxin Wang, Zhili Song, Janice D. Wagner, Catherine Pachuk, Romesh R. Subramanian   +4 more
doaj   +1 more source

A multicontrast MR atlas of the Wistar rat brain

NeuroImage, 2021
We describe a multi-contrast, multi-dimensional atlas of the Wistar rat acquired at microscopic spatial resolution using magnetic resonance histology (MRH). Diffusion weighted images, and associated scalar images were acquired of a single specimen with a
G. Allan Johnson, Rick Laoprasert, Robert J. Anderson, Gary Cofer, James Cook, Forrest Pratson, Leonard E. White   +6 more
doaj   +1 more source

Brain Tissue Conductivity Measurements with MR-Electrical Properties Tomography: An In Vivo Study [PDF]

, 2021
First in vivo brain conductivity reconstructions using Helmholtz MR-Electrical Properties Tomography (MR-EPT) have been published. However, a large variation in the reconstructed conductivity values is reported and these values differ from ex vivo ...
Vink, Jord J T, Mandija, Stefano, van den Berg, Cornelis A T, Neggers, Sebastian F W, Petrov, Petar I   +4 more
core  

Learnings and challenges to deploy an interprofessional and independent medical education programme to a new audience

Journal of European CME, 2017
The importance of interprofessional education (IPE) in continuing medical education and professional development has long been recognised by health organisations and academic societies, benefiting not only patient outcomes and interprofessional ...
Mieke L. Van Driel, Treasure M. McGuire, Richard Stark, Patrice Lazure, Tina Garcia, Lisa Sullivan   +5 more
doaj   +1 more source