Results 31 to 40 of about 116,601,803 (245)

Genetic risk for insomnia is associated with objective sleep measures in young and healthy good sleepers

Neurobiology of Disease, 2022
Insomnia disorder (ID) is the second most common neuropsychiatric disorder. Its socioeconomic burden is enormous while diagnosis and treatment are difficult.
Ekaterina Koshmanova, Vincenzo Muto, Daphne Chylinski, Charlotte Mouraux, Mathilde Reyt, Martin Grinard, Puneet Talwar, Erik Lambot, Christian Berthomier, Marie Brandewinder, Nasrin Mortazavi, Christian Degueldre, André Luxen, Eric Salmon, Michel Georges, Fabienne Collette, Pierre Maquet, Eus Van Someren, Gilles Vandewalle   +18 more
doaj   +1 more source

Dopamine Neuron Challenge Test for early detection of Parkinson’s disease

npj Parkinson's Disease, 2021
Diagnosing Parkinson’s disease (PD) before the clinical onset proves difficult because the hallmark PD symptoms do not manifest until more than 60% of dopamine neurons in the substantia nigra pars compacta have been lost.
Jingheng Zhou, Jicheng Li, Amy B. Papaneri, Nicholas P. Kobzar, Guohong Cui   +4 more
doaj   +1 more source

Timely coupling of sleep spindles and slow waves linked to early amyloid-β burden and predicts memory decline

eLife, 2022
Sleep alteration is a hallmark of ageing and emerges as a risk factor for Alzheimer’s disease (AD). While the fine-tuned coalescence of sleep microstructure elements may influence age-related cognitive trajectories, its association with AD processes is ...
Daphne Chylinski, Maxime Van Egroo, Justinas Narbutas, Vincenzo Muto, Mohamed Ali Bahri, Christian Berthomier, Eric Salmon, Christine Bastin, Christophe Phillips, Fabienne Collette, Pierre Maquet, Julie Carrier, Jean-Marc Lina, Gilles Vandewalle   +13 more
doaj   +1 more source

In Vivo Study of Natural Killer (NK) Cell Cytotoxicity Against Cholangiocarcinoma in a Nude Mouse Model. [PDF]

, 2018
BACKGROUND/AIM: Natural killer (NK) cells are one of the lymphocytes clinically used for various cancer types. Cytotoxicity of NK cells to cholangiocarcinoma (CC), however, has not yet been studied.
정인혜, 박승우
core   +1 more source

Biological Applications of Electron Paramagnetic Resonance Viscometry Using a ¹³C-Labeled Trityl Spin Probe

Molecules, 2021
Alterations in viscosity of biological fluids and tissues play an important role in health and diseases. It has been demonstrated that the electron paramagnetic resonance (EPR) spectrum of a 13C-labeled trityl spin probe (13C-dFT) is highly sensitive to ...
Murugesan Velayutham, Martin Poncelet, Timothy D. Eubank, Benoit Driesschaert, Valery V. Khramtsov   +4 more
doaj   +1 more source

Persistent Quantitative Vitality of Stem Cell Graft Is Necessary for Stabilization of Functional Brain Networks After Stroke

Frontiers in Neurology, 2019
Stem cell treatment after stroke has demonstrated substantial outcome improvement. However, monitoring of stem cell fate in vivo is still challenging and not routinely performed, yet important to quantify the role of the implanted stem cells on lesion ...
Claudia Green, Anuka Minassian, Stefanie Vogel, Michael Diedenhofen, Dirk Wiedermann, Mathias Hoehn, Mathias Hoehn, Mathias Hoehn   +7 more
doaj   +1 more source

Positive Effect of Cognitive Reserve on Episodic Memory, Executive and Attentional Functions Taking Into Account Amyloid-Beta, Tau, and Apolipoprotein E Status

Frontiers in Aging Neuroscience, 2021
Studies exploring the simultaneous influence of several physiological and environmental factors on domain-specific cognition in late middle-age remain scarce.
Justinas Narbutas, Justinas Narbutas, Daphne Chylinski, Maxime Van Egroo, Mohamed Ali Bahri, Ekaterina Koshmanova, Gabriel Besson, Vincenzo Muto, Christina Schmidt, Christina Schmidt, André Luxen, Evelyne Balteau, Christophe Phillips, Pierre Maquet, Pierre Maquet, Eric Salmon, Eric Salmon, Eric Salmon, Gilles Vandewalle, Christine Bastin, Christine Bastin, Fabienne Collette, Fabienne Collette   +22 more
doaj   +1 more source

Development of a sensitive ELISA to quantify apolipoprotein CIII in nonhuman primate serum

Journal of Lipid Research, 2011
Apolipoprotein CIII (apoCIII), a major constituent of triglyceride-rich lipoprotein, has been proposed as a key contributor to hypertriglyceridemia on the basis of its inhibitory effects on lipoprotein lipase.
Yuxin Wang, Zhili Song, Janice D. Wagner, Catherine Pachuk, Romesh R. Subramanian   +4 more
doaj   +1 more source

Printing in vivo [PDF]

Nature Methods, 2020
Intravital three-dimensional bioprinting enables the biofabrication of constructs in a pre-existing 3D matrix, such as inside tissues of live animals.
openaire   +2 more sources

CS1-specific single-domain antibodies labeled with Actinium-225 prolong survival and increase CD8+ T cells and PD-L1 expression in Multiple Myeloma

OncoImmunology, 2021
Multiple myeloma (MM) is a hematological malignancy characterized by the presence of clonal plasma cells in the bone marrow niche. Despite significant therapeutic advances, MM remains incurable for the majority of patients. Targeted radionuclide therapy (
Kim De Veirman, Janik Puttemans, Ahmet Krasniqi, Thomas Ertveldt, Heleen Hanssens, Ema Romao, Dirk Hose, Cleo Goyvaert, Philip Vlummens, Serge Muyldermans, Karine Breckpot, Frank Bruchertseifer, Alfred Morgenstern, Matthias D’Huyvetter, Nick Devoogdt   +14 more
doaj   +1 more source