Results 31 to 40 of about 3,388,289 (318)

Predicting unipolar and bipolar depression using inflammatory markers, neuroimaging and neuropsychological data: a machine learning study

open access: yesEuropean Psychiatry, 2023
Introduction About 60% of bipolar disorder (BD) cases are initially misdiagnosed as major depressive disorder (MDD), preventing BD patients from receiving appropriate treatment.
L. Raffaelli   +12 more
doaj   +1 more source

Multimodality Imaging of Silica and Silicon Materials In Vivo [PDF]

open access: yes, 2018
Recent progress in the development of silica? and silicon?based multimodality imaging nanoprobes has advanced their use in image?guided drug delivery, and the development of novel systems for nanotheranostic and diagnostic applications.
Mirkka P. Sarparanta   +7 more
core   +1 more source

The Design and Preclinical Evaluation of a Single-Label Bimodal Nanobody Tracer for Image-Guided Surgery

open access: yesBiomolecules, 2021
Intraoperative guidance using targeted fluorescent tracers can potentially provide surgeons with real-time feedback on the presence of tumor tissue in resection margins.
Pieterjan Debie   +10 more
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On Butler $B(2)$-groups decomposing over two base elements [PDF]

open access: yes, 2009
summary:A $B(2)$-group is a sum of a finite number of torsionfree Abelian groups of rank $1$, subject to two independent linear relations. We complete here the study of direct decompositions over two base elements, determining the cases where the ...
Metelli, Claudia, De Vivo, Clorinda
core   +1 more source

Beyond the Barrier: Targeted Radionuclide Therapy in Brain Tumors and Metastases

open access: yesPharmaceutics, 2019
Brain tumors are notoriously difficult to treat. The blood-brain barrier provides a sanctuary site where residual and metastatic cancer cells can evade most therapeutic modalities.
Janik Puttemans   +3 more
doaj   +1 more source

Mate genetic similarity affects mating behaviour but not maternal investment in mice

open access: yesScientific Reports, 2023
Maternal investment can affect the survival and development of offspring. Here we experimentally investigated in mice, whether females alter implantation rates and pup survival after embryo transfer depending on the genetic similarity with their ...
Kerstin E. Auer   +4 more
doaj   +1 more source

Limitations of ex vivo measurements for in vivo neuroscience [PDF]

open access: yesProceedings of the National Academy of Sciences, 2017
Significance Understanding the physiology of noninvasive brain stimulation requires precise knowledge of biophysical properties of brain tissue (e.g., conductivities). Numerous researchers have tried to measure these properties using in vitro, in vivo, and ex vivo preparations in nonhuman animals or human tissue, though findings have tended ...
Alexander, Opitz   +4 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Ultrasound imaging for assessing aortic phenotypes: A preclinical tool for measuring cardiac disease model progression and therapeutic effect

open access: yesWFUMB Ultrasound Open
Cardiac dysfunction is a common feature of numerous diseases, ranging from metabolic disorders like Mucopolysaccharidosis Type 1 (MPS I), a.k.a. Hurler syndrome to neuromuscular disorders such as Myotonic Dystrophy type 1 (DM1).
James Cao   +8 more
doaj   +1 more source

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