Results 41 to 50 of about 116,601,803 (245)

A multicontrast MR atlas of the Wistar rat brain

NeuroImage, 2021
We describe a multi-contrast, multi-dimensional atlas of the Wistar rat acquired at microscopic spatial resolution using magnetic resonance histology (MRH). Diffusion weighted images, and associated scalar images were acquired of a single specimen with a
G. Allan Johnson, Rick Laoprasert, Robert J. Anderson, Gary Cofer, James Cook, Forrest Pratson, Leonard E. White   +6 more
doaj   +1 more source

Learnings and challenges to deploy an interprofessional and independent medical education programme to a new audience

Journal of European CME, 2017
The importance of interprofessional education (IPE) in continuing medical education and professional development has long been recognised by health organisations and academic societies, benefiting not only patient outcomes and interprofessional ...
Mieke L. Van Driel, Treasure M. McGuire, Richard Stark, Patrice Lazure, Tina Garcia, Lisa Sullivan   +5 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Beyond the Barrier: Targeted Radionuclide Therapy in Brain Tumors and Metastases

Pharmaceutics, 2019
Brain tumors are notoriously difficult to treat. The blood-brain barrier provides a sanctuary site where residual and metastatic cancer cells can evade most therapeutic modalities.
Janik Puttemans, Tony Lahoutte, Matthias D’Huyvetter, Nick Devoogdt   +3 more
doaj   +1 more source

Predicting unipolar and bipolar depression using inflammatory markers, neuroimaging and neuropsychological data: a machine learning study

European Psychiatry, 2023
Introduction About 60% of bipolar disorder (BD) cases are initially misdiagnosed as major depressive disorder (MDD), preventing BD patients from receiving appropriate treatment.
L. Raffaelli, F. Colombo, F. Calesella, L. Fortaner-Uya, I. Bollettini, C. Lorenzi, E. Maggioni, E. Tassi, S. Poletti, R. Zanardi, F. Attanasio, F. Benedetti, B. Vai   +12 more
doaj   +1 more source

Aortic Slimgraft: Ex vivo and in vivo study [PDF]

Journal of Vascular Surgery, 2001
In this article we describe a method for assembling an endovascular graft within the aorta with a graft and then a stent introduced sequentially over a guidewire as separate components. In the ex vivo study, an endovascular graft that was 25 mm in diameter was introduced through a 9F introducer.
Kerr, Andrew S., Osende, Julio, Fallon, John T., Badimon, Juan   +3 more
openaire   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Ultrasound imaging for assessing aortic phenotypes: A preclinical tool for measuring cardiac disease model progression and therapeutic effect

WFUMB Ultrasound Open
Cardiac dysfunction is a common feature of numerous diseases, ranging from metabolic disorders like Mucopolysaccharidosis Type 1 (MPS I), a.k.a. Hurler syndrome to neuromuscular disorders such as Myotonic Dystrophy type 1 (DM1).
James Cao, Alex Jayyosi, Jennifer Nietupski, Giulio Tomassy, Ingeborg M. Langohr, Michelle Potter, Srinivas Rao, Dinesh S. Bangari, Xiaoyou Ying   +8 more
doaj   +1 more source

The Canmore Declaration: Statement of Principles for Planetary Health

Challenges, 2018
The term planetary health—denoting the interdependence between human health and place at all scales—emerged from the environmental and preventive health movements of the 1970–80s; in 1980, Friends of the Earth expanded the World Health Organization ...
Susan L. Prescott, Alan C. Logan, Glenn Albrecht, Dianne E. Campbell, Julian Crane, Ashlee Cunsolo, John W. Holloway, Anita L. Kozyrskyj, Christopher A. Lowry, John Penders, Nicole Redvers, Harald Renz, Jakob Stokholm, Cecilie Svanes, Ganesa Wegienka, on Behalf of inVIVO Planetary Health, of the Worldwide Universities Network (WUN)   +15 more
doaj   +1 more source

The Design and Preclinical Evaluation of a Single-Label Bimodal Nanobody Tracer for Image-Guided Surgery

Biomolecules, 2021
Intraoperative guidance using targeted fluorescent tracers can potentially provide surgeons with real-time feedback on the presence of tumor tissue in resection margins.
Pieterjan Debie, Noemi B. Declerck, Danny van Willigen, Celine M. Huygen, Bieke De Sloovere, Lukasz Mateusiak, Jessica Bridoux, Janik Puttemans, Nick Devoogdt, Fijs W. B. van Leeuwen, Sophie Hernot   +10 more
doaj   +1 more source