Results 51 to 60 of about 5,451,159 (308)

Reversal of aging-induced increases in aortic stiffness by targeting cytoskeletal protein-protein interfaces [PDF]

, 2018
Background: The proximal aorta normally functions as a critical shock absorber that protects small downstream vessels from damage by pressure and flow pulsatility generated by the heart during systole.
AortaGen Consortium, the, Bekaert, Sofie, Chiu, Joanna G, De Backer, Gui, De Bacquer, Dirk, De Buyzere, Marc, De Meyer, Tim, Gao, Yuan Z, Gillebert, Thierry, Leavis, Paul, Li, Qian, Mitchell, GF, Morgan, Kathleen G, Nicholson, Christopher J, Porter, Tyrone, Rietzschel, Ernst, Saphirstein, Robert J, Segers, Patrick, Singh, Kuldeep, Van Bortel, Lucas, Verwoert, Germaine C   +20 more
core   +2 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Endocannabinoid signaling is critical for habit formation

Frontiers in Integrative Neuroscience, 2007
Extended training can induce a shift in behavioral control from goal-directed actions, which are governed by action-outcome contingencies and sensitive to change in the expected value of the outcome, to habits which are less dependent on action-outcome ...
Monica R. F Hilário, Emily Clouse, Henry H Yin, Rui M Costa   +3 more
doaj   +1 more source

Uji Aktivitas Antidislipidemia In Vivo Fraksi Ekstrak Daun Salam (Eugenia Polyantha) pada Tikus Galur Wistar yang Diinduksi Diet Tinggi Lemak [PDF]

, 2014
Dislipidemia merupakan faktor resiko berbagai penyakit yang masih menjadi masalah besar di Indonesia. Daun salam (Eugenia polyantha) terbukti dapat digunakan sebagai antidislipidemia.Untuk mengetahui fraksi apakah yang berpengaruh terhadap aktivitas ...
Chalista, S. (Shelvia), Fam, F. I. (Felicia), Irmadoly, N. (Nini), Se, H. S. (Ha), Wirajaya, F. (Frandy)   +4 more
core  

Aortic Slimgraft: Ex vivo and in vivo study [PDF]

Journal of Vascular Surgery, 2001
In this article we describe a method for assembling an endovascular graft within the aorta with a graft and then a stent introduced sequentially over a guidewire as separate components. In the ex vivo study, an endovascular graft that was 25 mm in diameter was introduced through a 9F introducer.
Kerr, Andrew S., Osende, Julio, Fallon, John T., Badimon, Juan   +3 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

In vivo detection of lamellocytes in Drosophila melanogaster. [PDF]

, 2009
Drosophila has recently become a powerful model organism for studies of innate immunity. The cellular elements of innate immunity in Drosophila, the hemocytes, have been characterized by morphological criteria, molecular markers, and cell-type-specific ...
Brand, Braun, Carton, Evans, Evans, Goto, Hartenstein, Hoffmann, Hultmark, Konrad, Kurucz, Kurucz, Kurucz, Lanot, Metaxakis, Márkus, Márkus, Zettervall   +17 more
core   +1 more source

Desmosomes In Vivo [PDF]

Dermatology Research and Practice, 2010
The structure, function, and regulation of desmosomal adhesion in vivo are discussed. Most desmosomes in tissues exhibit calcium‐independent adhesion, which is strongly adhesive or “hyperadhesive”. This is fundamental to tissue strength. Almost all studies in culture are done on weakly adhesive, calcium‐dependent desmosomes, although hyperadhesion can ...
openaire   +3 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Homeostatic sleep regulation in the absence of the circadian sleep‐regulating component: effect of short light–dark cycles on sleep–wake stages and slow waves

BMC Neuroscience, 2021
Background Aside from the homeostatic and circadian components, light has itself an important, direct as well as indirect role in sleep regulation. Light exerts indirect sleep effect by modulating the circadian rhythms. Exposure to short light-dark cycle
Örs Szalontai, Attila Tóth, Máté Pethő, Dóra Keserű, Tünde Hajnik, László Détári   +5 more
doaj   +1 more source