Results 61 to 70 of about 7,607,147 (352)

Technical Development of a New Semispherical Radiofrequency Bipolar Device (RONJA): Ex Vivo and In Vivo Studies [PDF]

, 2014
The aim of this study is to inform about the development of a new semispherical surgical instrument for the bipolar multielectrode radiofrequency liver ablation.
Crha, M, Delongova, P, Grepl, J, Habib, NA, Hasal, M, Ihnat, P, Jurcikova, J, Nowakova, J, Ostruszka, P, Palecek, J, Penhaker, M, Salounova, D, Skrobankova, M, Vavra, P, Zonca, P   +14 more
core   +5 more sources

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

FEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura, Lixiang Wang, Nao Hasuzawa, Ayako Nagayama, Sawako Moriyama, Kenji Ashida, Yoshinori Moriyama, Masatoshi Nomura, Ken Yamamoto   +8 more
wiley   +1 more source

Uji Aktivitas Antimalaria In Vivo dari Beberapa Fraksi Ekstrak Kulit Buah Manggis (Garcinia Manggostana Linn) pada Mencit (Mus Musculus ) yang Diinfeksi dengan Plasmodium Berghei [PDF]

, 2013
Malaria disease is still one public health problem in the world and affect the infant mortality rate, under five and pregnant women. The purpose of this study was to recognize in vivo antimalarial activity from hexane fraction, ethyl acetate, and ...
Aamruna, Y. (Yaum), Effendi, Z. (Zulham), Iqbal, M. (Muhammad), Suryawati, S. (Suryawati)   +3 more
core  

Photoacoustic computed tomography guided microrobots for targeted navigation in intestines in vivo [PDF]

, 2020
Tremendous progress in synthetic micro/nanomotors has been made for potential biomedical applications. However, existing micro/nanomotor platforms are inefficient for deep tissue imaging and motion control in vivo.
Gao, Wei, Hu, Peng, Li, Lei, Wang, Lihong V., Wu, Zhiguang, Yang, Yiran   +5 more
core  

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Homeostatic sleep regulation in the absence of the circadian sleep‐regulating component: effect of short light–dark cycles on sleep–wake stages and slow waves

BMC Neuroscience, 2021
Background Aside from the homeostatic and circadian components, light has itself an important, direct as well as indirect role in sleep regulation. Light exerts indirect sleep effect by modulating the circadian rhythms. Exposure to short light-dark cycle
Örs Szalontai, Attila Tóth, Máté Pethő, Dóra Keserű, Tünde Hajnik, László Détári   +5 more
doaj   +1 more source

Prevalence of Genetic Diamine Oxidase (DAO) Deficiency in Female Patients with Fibromyalgia in Spain

Biomedicines, 2023
Diamine oxidase (DAO) is an enzyme that metabolizes intestinal histamine. Single nucleotide polymorphisms (SNPs) of the Amine Oxidase Copper Containing 1 (AOC1) gene can lead to low enzymatic activity or functionality in histamine metabolism.
Gülşah Okutan, Eva Ruiz Casares, Teresa Perucho Alcalde, Guerthy Melissa Sánchez Niño, Bruno F. Penadés, Ana Terrén Lora, Lorena Torrente Estríngana, Sara López Oliva, Ismael San Mauro Martín   +8 more
doaj   +1 more source

Nonscanning large-area Raman imaging for ex vivo/in vivo skin cancer discrimination

, 2018
Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring the technique
Darvin, Maxim E., Gersonde, Ingo, Moralejo, Benito, Roth, Martin M., Schleusener, Johannes, Schmälzlin, Elmar, Thiede, Gisela   +6 more
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Noninvasive in vivo 3D bioprinting

Science Advances, 2020
The subcutaneously injected bioink was noninvasively printed into customized living tissue constructs in situ. Three-dimensional (3D) printing technology has great potential in advancing clinical medicine.
Yuwen Chen, Jiumeng Zhang, Xuan Liu, Shuai Wang, J. Tao, Yulan Huang, Wenbi Wu, Yang Li, K. Zhou, Xiawei Wei, Shaochen Chen, Xiang Li, Xuewen Xu, L. Cardon, Z. Qian, M. Gou   +15 more
semanticscholar   +1 more source