Results 61 to 70 of about 6,961,893 (372)
Non-contact acoustic micro-tapping optical coherence elastography for quantification of corneal anisotropic elasticity: in vivo rabbit study [PDF]
arXiv, 2023 Purpose. To demonstrate accurate measurement of corneal elastic moduli in vivo with non-contact and non-invasive optical coherence elastography. Methods. Elastic properties (in-plane Young's modulus E and both in-plane, u, and out-of-plane, G, shear moduli) of rabbit cornea were quantified in vivo using non-contact dynamic Acoustic micro-Tapping ...
arxiv
Bone in vivo: Surface mapping technique [PDF]
PLoS ONE, 2011, 7(3): e32926, 2010 Bone surface mapping technique is proposed on the bases of two kinds of uniqueness of bone in vivo, (i) magnitude of the principal moments of inertia, (ii) the direction cosines of principal axes of inertia relative to inertia reference frame. We choose the principal axes of inertia as the bone coordinate system axes. The geographical marks such as the
arxiv +1 more source
Limitations of ex vivo measurements for in vivo neuroscience [PDF]
Proceedings of the National Academy of Sciences, 2017 Significance Understanding the physiology of noninvasive brain stimulation requires precise knowledge of biophysical properties of brain tissue (e.g., conductivities). Numerous researchers have tried to measure these properties using in vitro, in vivo, and ex vivo preparations in nonhuman animals or human tissue, though findings have tended ...
Michael P. Milham +6 more
openaire +3 more sources
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
In Vivo Magnetic Resonance Spectroscopy by J-Locked Chemical Shift Encoding for Determination of Neurochemical Concentration and Transverse Relaxation Time [PDF]
arXiv, 2023 Cell pathology in neuropsychiatric disorders has mainly been accessible by analyzing postmortem tissue samples. Although molecular transverse relaxation informs local cellular microenvironment via molecule-environment interactions, precise determination of the transverse relaxation times of molecules with scalar couplings (J), such as glutamate and ...
arxiv
Experimental Characterization of In Vivo Wireless Communication Channels [PDF]
VTC Fall, 2015 IEEE 82nd, Boston, MA, 2015, pp. 1-2, 2016 In vivo wireless medical devices have a critical role in healthcare technologies due to their continuous health monitoring and noninvasive surgery capabilities. In order to fully exploit the potential of such devices, it is necessary to characterize the in vivo wireless communication channel which will help to build reliable and high-performance ...
arxiv +1 more source
Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases
FEBS Letters, EarlyView.The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher +6 more
wiley +1 more source
In vivo genome editing using Staphylococcus aureus Cas9
Nature, 2015 The RNA-guided endonuclease Cas9 has emerged as a versatile genome-editing platform. However, the size of the commonly used Cas9 from Streptococcus pyogenes (SpCas9) limits its utility for basic research and therapeutic applications that use the highly ...
F. Ran +12 more
semanticscholar +1 more source
Noninvasive in vivo 3D bioprinting
Science Advances, 2020 The subcutaneously injected bioink was noninvasively printed into customized living tissue constructs in situ. Three-dimensional (3D) printing technology has great potential in advancing clinical medicine.
Yuwen Chen +15 more
semanticscholar +1 more source
Insertion of the FeB cofactor in cNORs lacking metal inserting chaperones
FEBS Letters, EarlyView.Nitric oxide reductase is an enzyme found in the bacterial denitrification pathway. The NOR active site contains a non‐heme iron, often, but not always inserted with the assistance of chaperones. Here, we study the insertion of FeB in the subfamily of cNORs lacking chaperones and found a putative channel, conserved in the family, perhaps enabling the ...
Sofia Appelgren, Pia Ädelroth
wiley +1 more source