Results 61 to 70 of about 5,659,897 (340)
Neuroprotective effects of carnitinoid compounds in rodent cellular and in vivo models of mitochondrial complex I dysfunction [PDF]
, 2019 Rotenone-mediated mitochondrial complex I inhibition was used to model Parkinson’s disease-like syndrome in Lewis rats. Tyrosine hydroxylase immunolabeling demonstrated a decrease in the number of dopaminergic neurons as well as aberrant morphology in ...
Steliou, Kosta
core
In Vivo Localization of Fas-Associated Death Domain Protein in the Nucleus and Cytoplasm of Normal Thyroid and Liver Cells [PDF]
, 2009 FADD (Fas-associated death domain) is the main death receptor adaptor molecule that transmits apoptotic signal. Recently, FADD protein was shown to be expressed both in the cytoplasm and nucleus of in vitro cell lines. In contrast to the cytoplasmic FADD,
Chiocchia, Gilles +2 more
core +5 more sources
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
WFUMB Ultrasound OpenCardiac dysfunction is a common feature of numerous diseases, ranging from metabolic disorders like Mucopolysaccharidosis Type 1 (MPS I), a.k.a. Hurler syndrome to neuromuscular disorders such as Myotonic Dystrophy type 1 (DM1).
James Cao +8 more
doaj +1 more source
The Canmore Declaration: Statement of Principles for Planetary Health
Challenges, 2018 The term planetary health—denoting the interdependence between human health and place at all scales—emerged from the environmental and preventive health movements of the 1970–80s; in 1980, Friends of the Earth expanded the World Health Organization ...
Susan L. Prescott +15 more
doaj +1 more source
Aktivitas Antiplasmodium in Vivo Fraksi N-butanol Kulit Batang Mahoni (Swietenia Mahagoni) Dan Asam Klorogenat [PDF]
, 2011 An antiplasmodial activity of n-butanol fraction from mahoni bark extract (Swietenia mahagoni Jacq.) and pure compound chlorogenic acid were investigated on white male miceSwiss derivated strain which were infected by Plasmodium berghei ANKA strain ...
Lukmayani, Y. (Yani) +3 more
core
Nonscanning large-area Raman imaging for ex vivo/in vivo skin cancer discrimination
, 2018 Imaging Raman spectroscopy can be used to identify cancerous tissue. Traditionally, a step-by-step scanning of the sample is applied to generate a Raman image, which, however, is too slow for routine examination of patients. By transferring the technique
Darvin, Maxim E. +6 more
core +1 more source
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
Circadian regulation of human cortical excitability
Nature Communications, 2016 Cognitive performance is impaired after prolonged wakefulness, yet the contribution of circadian rhythms for proper brain function remains unclear. Here the authors show that cortical excitability measured using TMS exhibits robust circadian dynamics ...
Julien Q. M. Ly +15 more
doaj +1 more source
Endocannabinoid signaling is critical for habit formation
Frontiers in Integrative Neuroscience, 2007 Extended training can induce a shift in behavioral control from goal-directed actions, which are governed by action-outcome contingencies and sensitive to change in the expected value of the outcome, to habits which are less dependent on action-outcome ...
Monica R. F Hilário +3 more
doaj +1 more source