Results 21 to 30 of about 2,222,057 (269)

Effects of Hyaluronic Acid on Three Different Cell Types of the Periodontium in a Novel Multi-Culture Cell Plate: An Exploratory Study

Biomolecules
Hyaluronic acid (HA) has received considerable attention in the reconstruction of lost periodontal tissues. HA has been proposed to play a role in cell proliferation, differentiation, migration, and cell–matrix as well as cell–cell interactions. Although
Alessio Barbieri, Luciano Pitzurra, Bruno Loos, Ineke D. C. Jansen   +3 more
doaj   +1 more source

Therapeutic properties of Algerian propolis in skin wound healing with significant tissue loss

Revista Científica
This study investigates the therapeutic properties of Algerian propolis in skin wound healing with significant tissue loss. It includes an in vitro phase to formulate an ethanolic extract of Algerian propolis (EEPA) ointment and evaluate its ...
Abdellatif Boudra, Rachid Merati , Berrani Abdelkader, Wassim Yezli , Helali Hadil, Imen Henni   +5 more
doaj   +1 more source

Nonviral Gene Therapy for Cancer: A Review

Diseases, 2018
Although the development of effective viral vectors put gene therapy on the road to commercialization, nonviral vectors show promise for practical use because of their relative safety and lower cost.
Chiaki Hidai, Hisataka Kitano
doaj   +1 more source

Personalized Zebrafish Models for Fusion‐Positive Pediatric Sarcomas

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Clinical sequencing efforts have revolutionized our approaches to categorizing pediatric cancers in real time. This has dramatically improved our ability to profile pediatric tumors, identify actionable vulnerabilities, and influence clinical care.
Lisa H. Hall, Emma N. Harrison, Genevieve C. Kendall   +2 more
wiley   +1 more source

Formulation and Optimization of Repaglinide Nanoparticles Using Microfluidics for Enhanced Bioavailability and Management of Diabetes

Biomedicines, 2023
The technologies for fabrication of nanocrystals have an immense potential to improve solubility of a variety of the poor water-soluble drugs with subsequent enhanced bioavailability.
Mubashir Ahmad, Shahzeb Khan, Syed Muhammad Hassan Shah, Muhammad Zahoor, Zahid Hussain, Haya Hussain, Syed Wadood Ali Shah, Riaz Ullah, Amal Alotaibi   +8 more
doaj   +1 more source

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

Safety assessment and in vitro cytotoxicity profiling of fruiting bodies from Lentinula edodes (shiitake) strains in HeLa and MCF-7 cell lines

Scientific Reports
Medicinal mushrooms offer diverse therapeutic benefits, but proper administration is crucial to avoid long-term health issues linked to fungal toxicity.
Sujata Makkar, Kiran Nehra, Ajay Singh, Sudheer Kumar Annepu   +3 more
doaj   +1 more source

Local estradiol deposition in a rat rotator cuff repair model: proof of concept

JSES International
Background: Local delivery of hormones could potentially provide local benefits to bone and enthesis while avoiding systemic side effects. The objective of this study was to demonstrate proof of concept for local deposition of estradiol in a rat rotator ...
Peter N. Chalmers, MD, Michael J. Jurynec, PhD, Austin M. Hickey, MS, T. Wade Fallin, MS, Antonio C. Zelada, BS, Matthew Honeggar, BS, James M. Hotaling, MD, Benjamin Emery, MPhil, Robert Tashjian, MD   +8 more
doaj   +1 more source

In vivo Modulatory Effect of Coffee (Coffea canephora var. Robusta) on the Expression Levels of Murine microRNA-124-3p Associated with Antioxidant Defenses

eFood, 2019
Antioxidant activity is one of the most studied properties of coffee as a beverage, and is mainly ascribed to its polyphenol content, although there is limited scientific literature regarding its mechanism of action at the molecular level.
Valeria Curti, Manuela Verri, Alessandra Baldi, Marco Dacrema, Irene Masiello, Maurizia Dossena, Maria Daglia   +6 more
doaj   +1 more source