Results 21 to 30 of about 2,568,108 (218)

Intragastric Carbon Dioxide Release Prolongs the Gastric Residence Time of Postprandially Administered Caffeine

Pharmaceutics, 2023
Sparkling water is said to increase gastric motility by the release of carbon dioxide, thereby potentially affecting the pharmacokinetics of orally administered drugs.
Stefan Senekowitsch, Constantin Foja, Toni Wildgrube, Philipp Schick, Christoph Rosenbaum, Julius Krause, Friederike Brokmann, Marie-Luise Kromrey, Stefan Engeli, Werner Weitschies, Michael Grimm   +10 more
doaj   +1 more source

"Ex vivo" and "in vivo" studies to assess chemical effects on steroidogenesis in fish: development and application of methods [PDF]

, 2011
The aquatic environment receives many chemical substances of natural or anthropogenic origin, which can influence the endocrine functions and health of wildlife.
a Marca Pereira, Luz Maria
core   +1 more source

Anxiolytic-like Effect of Quercetin Possibly through GABA Receptor Interaction Pathway: In Vivo and In Silico Studies

Molecules, 2022
Scientific evidence suggests that quercetin (QUR) has anxiolytic-like effects in experimental animals. However, the mechanism of action responsible for its anxiolytic-like effects is yet to be discovered.
Md. Shahazul Islam, Rajib Hossain, Taukir Ahmed, Md. Mizanur Rahaman, Khattab Al-Khafaji, Rasel Ahmed Khan, Chandan Sarkar, Mehedi Hasan Bappi, Edlane Martins de Andrade, Isaac Moura Araújo, Henrique Douglas Melo Coutinho, Grażyna Kowalska, Radosław Kowalski, Muhammad Asif Hanif, Muhammad Torequl Islam   +14 more
doaj   +1 more source

Preparation and In Vitro-In Vivo Evaluation of Luteolin Loaded Gastroretentive Microsponge for the Eradication of Helicobacter pylori Infections

Pharmaceutics, 2021
The current study aimed to develop a luteolin gastric floating microsponge for targeting Helicobacter pylori. The microsponge formulations were prepared by a quasi-emulsion method, and then evaluated for various physicochemical variables.
Mohammed Jafar, Mohammed Salahuddin, Mohd Sajjad Ahmad Khan, Yasir Alshehry, Nazar Radwan Alrwaili, Yazeed Ali Alzahrani, Syed Sarim Imam, Sultan Alshehri   +7 more
doaj   +1 more source

Effects of Hyaluronic Acid on Three Different Cell Types of the Periodontium in a Novel Multi-Culture Cell Plate: An Exploratory Study

Biomolecules
Hyaluronic acid (HA) has received considerable attention in the reconstruction of lost periodontal tissues. HA has been proposed to play a role in cell proliferation, differentiation, migration, and cell–matrix as well as cell–cell interactions. Although
Alessio Barbieri, Luciano Pitzurra, Bruno Loos, Ineke D. C. Jansen   +3 more
doaj   +1 more source

In vivo imaging and quantitative analysis of leukocyte directional migration and polarization in inflamed tissue [PDF]

, 2009
Directional migration of transmigrated leukocytes to the site of injury is a central event in the inflammatory response. Here, we present an in vivo chemotaxis assay enabling the visualization and quantitative analysis of subtype-specific directional ...
Alexander Georg Khandoga, Peter Bihari, Khandoga, Andrej, Reichel, Christoph Andreas, Rehberg, Markus, Fritz Krombach, Christoph Andreas Reichel, Markus Rehberg, Bihari, Peter, Krombach, Fritz, Khandoga, Alexander Georg, Andrej Khandoga   +11 more
core   +1 more source

Therapeutic properties of Algerian propolis in skin wound healing with significant tissue loss

Revista Científica
This study investigates the therapeutic properties of Algerian propolis in skin wound healing with significant tissue loss. It includes an in vitro phase to formulate an ethanolic extract of Algerian propolis (EEPA) ointment and evaluate its ...
Abdellatif Boudra, Rachid Merati , Berrani Abdelkader, Wassim Yezli , Helali Hadil, Imen Henni   +5 more
doaj   +1 more source

Nonviral Gene Therapy for Cancer: A Review

Diseases, 2018
Although the development of effective viral vectors put gene therapy on the road to commercialization, nonviral vectors show promise for practical use because of their relative safety and lower cost.
Chiaki Hidai, Hisataka Kitano
doaj   +1 more source

Formulation and Optimization of Repaglinide Nanoparticles Using Microfluidics for Enhanced Bioavailability and Management of Diabetes

Biomedicines, 2023
The technologies for fabrication of nanocrystals have an immense potential to improve solubility of a variety of the poor water-soluble drugs with subsequent enhanced bioavailability.
Mubashir Ahmad, Shahzeb Khan, Syed Muhammad Hassan Shah, Muhammad Zahoor, Zahid Hussain, Haya Hussain, Syed Wadood Ali Shah, Riaz Ullah, Amal Alotaibi   +8 more
doaj   +1 more source

Safety assessment and in vitro cytotoxicity profiling of fruiting bodies from Lentinula edodes (shiitake) strains in HeLa and MCF-7 cell lines

Scientific Reports
Medicinal mushrooms offer diverse therapeutic benefits, but proper administration is crucial to avoid long-term health issues linked to fungal toxicity.
Sujata Makkar, Kiran Nehra, Ajay Singh, Sudheer Kumar Annepu   +3 more
doaj   +1 more source