Results 41 to 50 of about 2,568,108 (218)

Research progress in biodegradable Zn-based materials for orthopedic applications

Cailiao gongcheng, 2022
In recent years, zinc alloys have shown great potential as orthopedic plant materials because of their excellent biocompatibility, osteoinductive and biodegradation activities in vivo.
SUN Jiang, SHI Zhangzhi, LI Yageng, LI Xiangmin, LI Weishi, WANG Luning   +5 more
doaj   +1 more source

Differentiating intratumoral melanocytes from Langerhans cells in nonmelanocytic pigmented skin tumors in vivo by label-free third-harmonic generation microscopy

, 2017
Morphology and distribution of melanocytes are critical imaging information for the diagnosis of melanocytic lesions. However, how to image intratumoral melanocytes noninvasively in pigmented skin tumors is seldom investigated. Third-harmonic generation (
廖怡華, Weng, Wei-Hung;Liao, Yi-Hua;Tsai, Ming-Rung;Wei, Ming-Liang;Huang, Hsin-Yi;Sun, Chi-Kuang   +1 more
core   +1 more source

Botanical Flavonoids: Efficacy, Absorption, Metabolism and Advanced Pharmaceutical Technology for Improving Bioavailability

Molecules
Flavonoids represent a class of natural plant secondary metabolites with multiple activities including antioxidant, antitumor, anti-inflammatory, and antimicrobial properties.
Lei Hu, Yiqing Luo, Jiaxin Yang, Chunsong Cheng   +3 more
doaj   +1 more source

Morphofunctional Characteristics of the Hippocampus of White Rats in the Acute Period After Severe Traumatic Brain Injury During the Use of L-lysine Aescinat

Неотложная медицинская помощь, 2021
Aim of study. The study is devoted to the effect of L-lysine aescinat on the nervous tissue of the CA1 and CA3 fields of the hippocampus of the brain of white rats in the acute period after severe traumatic brain injury (TBI).Material and methods.
I. P. Koshman, A. Yu. Shoronova, S. S. Stepanov, A. G. Kalinichev, V. A. Akulinin, A. S. Stepanov, D. B. Avdeyev, V. L. Molchanova   +7 more
doaj   +1 more source

Use and reporting of historical control data for regulatory studies

EFSA Journal
The provision of historical control data (HCD) is a data requirement for pesticide active substances established by European legislation. HCD are data from studies conducted under the same or similar conditions as the toxicity study under assessment ...
EFSA Panel on Plant Protection Products and their Residues (PPR), Tamara Coja, Pauline Adriaanse, Judy Choi, Antonio Finizio, Maeva Giraudo, Thomas Kuhl, Francesca Metruccio, Martin Paparella, Silvia Pieper, Eugenio Scanziani, Ivana Teodorovic, Paul Van der Brink, Peter Craig, Bertrand Desprez, Ian Dewhurst, Emily McVey, Arianna Chiusolo, Anna Lanzoni, Sara Levorato, Laura Martino, Tommaso Giorgi, Martin Wilks   +22 more
doaj   +1 more source

In vitro and in vivo validation of human and goat chondrocyte labeling by green fluorescent protein lentivirus transduction [PDF]

, 2010
We investigated whether human articular chondrocytes can be labeled efficiently and for long-term with a green fluorescent protein (GFP) lentivirus and whether the viral transduction would influence cell proliferation and tissue-forming capacity.
Candrian, Christian, Gianni-Barrera, Roberto, Juelke, Henriette, Martin, Ivan, Jaquiery, Claude, Acharya, Chitrangada, Barbero, Andrea, Miot, Sylvie, Pelttari, Karoliina, Mainil-Varlet, Pierre   +9 more
core   +1 more source

Oil-based and oil-free formulations for enhancing cannabidiol bioavailability

Journal of Cannabis Research
Background Cannabidiol (CBD) exhibits therapeutic potential due to its analgesic, anxiolytic, anti-inflammatory, and anticonvulsant effects. However, its oral bioavailability is limited by poor water solubility and extensive first-pass metabolism ...
Petr Jelínek, Anežka Klouček, Ashley Hannah George, Hynek Housar, Petr Kozlík, Tomáš Křížek, Pavel Ryšánek, Martin Šíma, Ondřej Slanař, Miroslav Šoóš   +9 more
doaj   +1 more source

Antiplasmodial and in vitro antioxidant potentials of crude aqueous and methanol extracts of Chasmanthera dependens (Hochst)

Bulletin of the National Research Centre, 2022
Background Malaria is a major cause of death in tropical countries such as Nigeria. Chasmanthera dependens (Hochst) is a wild plant used by traditional healers for the treatment of malaria and other health challenges.
Conrad Kenechukwu Enenebeaku, Cynthia Ekwy Ogukwe, Christian Okechukwu Nweke, Sylvia Onyinyechi Anyado-Nwadike, Martin Obi, Ijeoma Akunna Duru, Uchechi Emmanuela Enenebeaku, Odangowei I. Ogidi   +7 more
doaj   +1 more source

In Vivo Antihypertensive and Ex Vivo Vasodilatory Studies of Taxifolin

Pharmaceuticals
Background: Hypertension is a leading cause of cardiovascular morbidity and mortality. Taxifolin has shown cardiovascular benefits, but its antihypertensive mechanisms remain poorly defined. This study aimed to comprehensively elucidate the molecular mechanisms underlying Taxifolin’s blood pressure-lowering effects by integrating network pharmacology ...
Xuye Wang, Xiangyang Xu, Wan Yin Tew, Liyun Ouyang, Xiaoning Yang, Hui Wei Loh, Wen Xu, Wei Xu, Mun Fei Yam   +8 more
openaire   +3 more sources

An in vivo study of compulsions

Journal of Obsessive-Compulsive and Related Disorders, 2021
Abstract Leading models of obsessive-compulsive disorder (OCD) assume that compulsions are enacted to neutralize distress over obsessions. However, lab-based research suggests that once a compulsion starts factors other than distress cause it to persist.
Jasmine Dean, Christine Purdon
openaire   +2 more sources