Dosimetry for 6-[18F]Fluoro-L-DOPA in humans based on in vivo microPET scans and ex vivo tissue distribution in mice [PDF]
, 2012 Radiation dosimetry of new radiopharmaceuticals generally starts with studies in small animals such as mice and rats. The traditional technique has long been ex vivo measurement of the biodistribution over time using harvested organs at different times ...
Lemaire, Christian +8 more
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A Correlative Imaging Study of in vivo and ex vivo Biodistribution of Solid Lipid Nanoparticles
International Journal of Nanomedicine, 2020 Silvia Mannucci,1 Federico Boschi,2,* Barbara Cisterna,1,* Elisabetta Esposito,3 Rita Cortesi,3 Claudio Nastruzzi,3 Enrica Cappellozza,1 Paolo Bernardi,1 Andrea Sbarbati,1 Manuela Malatesta,1 Laura Calderan1 1Department of Neurosciences, Biomedicine and ...
Mannucci S +10 more
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Test No. 427: Skin Absorption: In Vivo Method [electronic resource] /
, 2004 The in vivo percutaneous absorption study set out in this Test Guideline provides the linkage necessary to extrapolate from oral studies when making safety assessments following dermal exposure. The in vivo method, described in this guideline, allows the
Organisation for Economic Co-operation and Development.
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Toxicity of Crepis lacera in grazing ruminants
BMC Veterinary Research, 2018 Background Crepis lacera is a plant from the Asteraceae family that is common in the Mediterranean region. Farmers believe that this plant may be deadly to small ruminants in areas of southern Italy.
Rosario Russo +9 more
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IN VIVO STUDY OF THE SV2A PROTEIN IN AN EPILEPTIC RAT MODEL
, 2017 Introduction Epilepsy is one of the commonest neurological disorders, affecting more than 60 million people worldwide [1]. New and effective antiepileptic drugs mainly target the SV2A protein [2] but its actual role is still largely unknown.
Lemaire, Christian +10 more
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In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extract
Plant TrendsCordia macleodii has long served as a medicinal plant for its hepatoprotective and wound healing properties. People utilize this plant in treating various diseases due to the presence of relatively high levels of flavonoids, alkaloids, steroids, and ...
Sajidur Rahman Akash +7 more
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In VivoCytogenetic Studies on Aspartame [PDF]
Comparative and Functional Genomics, 2010 Aspartame (a-Laspartyl-L-phenylalanine 1-methylester) is a dipeptide low-calorie artificial sweetener that is widely used as a nonnutritive sweetener in foods and drinks. The safety of aspartame and its metabolic breakdown products (phenylalanine, aspartic acid and methanol) was investigatedin vivousing chromosomal aberration (CA) test and sister ...
openaire +2 more sources
An in vivo and ex-vivo study of biodistribution and accumulation of Quantum Dots
, 2009 In the present study we investigate the impact of nanoparticles in an in vivo and ex-vivo system. At this aim Balb-C female mice are treated with Quantum Dots (QDs) (1:5 dilutions of commercial solution 2 μM /0.01ml/g mouse, i.v) and sacrificed 3h, 24h ...
FRANCESCHI, Antonia +7 more
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Video_2_In vivo Two-Photon Imaging of Anesthesia-Specific Alterations in Microglial Surveillance and Photodamage-Directed Motility in Mouse Cortex.AVI [PDF]
, 2019 Two-photon imaging of fluorescently labeled microglia in vivo provides a direct approach to measure motility of microglial processes as a readout of microglial function that is crucial in the context of neurodegenerative diseases, as well as to ...
Sun, Weilun +13 more
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Sealing ability of newer generation bonding agents in primary teeth - an in vivo study
, 2010 Aim: The purpose of the study was to compare the ability of Xeno III (sixth generation dentin bonding agent) to iBond (seventh generation dentin bonding agent) in reducing microleakage around class V composite resin restorations in primary teeth.Methods:
Chetan Bhat
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