Results 1 to 10 of about 433 (162)

An effective inactivant based on singlet oxygen-mediated lipid oxidation implicates a new paradigm for broad-spectrum antivirals [PDF]

open access: yesRedox Biology, 2020
Emerging viral pathogens cause substantial morbidity and pose a severe threat to health worldwide. However, a universal antiviral strategy for producing safe and immunogenic inactivated vaccines is lacking. Here, we report an antiviral strategy using the
Shengli Ming, Guo-Yu Yang, Bei-Bei Chu
exaly   +4 more sources

Inactivated vaccine against Aujeszky's disease [PDF]

open access: yesVeterinary World, 2021
Background and Aim: The Aujeszky's disease, also known as Pseudorabies, remains one of the most problematic fulminant diseases in domestic animals, affecting the central nervous system.
Zhanat B. Kondibaeva   +9 more
doaj   +2 more sources

Preparation of an Inactivated Peste des Petits Ruminants Vaccine and Its Comparative Immunogenicity Evaluation in an Animal Model [PDF]

open access: yesArchives of Razi Institute, 2021
Peste des petits ruminants (PPR) is a highly contagious disease that is considered a major threat to the small livestock industry. Although vaccination via live-attenuated PPR vaccine is a main controlling strategy in the endemic area, during PPR ...
M Akbarian   +4 more
doaj   +2 more sources

THE USE OF BINARY ETHYLENIMINE AND FORMALIN AS INACTIVANTS FOR PRODUCTION OF INACTIVATED NEWCASTLE DISEASE VACCINE [PDF]

open access: yesAssiut Veterinary Medical Journal, 1996
The use of Binary Ethylenimine as inactivant for Newcastle virus give a promising result as it has no effect on the antiginecity of the virus when used or 0,03 M at the same time it had completely in a concentration of 0.01M reduced the virulence of the ...
SOAD, M. SOLIMAN   +3 more
exaly   +2 more sources

Inactivation of foot and mouth disease virus for vaccine production [PDF]

open access: yesВетеринария сегодня, 2023
Inactivation is the loss by a virus of ability to reproduce and infect susceptible animals while retaining its antigenic properties. In this paper, the effectiveness of aminoethylethanolamine when used as an FMDV inactivant is shown.
D. V. Mikhalishin   +3 more
doaj   +2 more sources

Selection of conditions for effective inactivation of Pseudopestis avium virus (Paramyxoviridae: Orthoavulovirus: Avian orthoavulovirus 1) for the production of a Newcastle disease vaccine

open access: yesВопросы вирусологии, 2023
Introduction. Newcastle disease (ND) is classified as especially dangerous pathogen. Its primary source is an infected or recovered bird. The virus shedding begins just in a day after infection, and virus remains in the body for another 2-4 months after ...
Kuanish K. Jekebekov   +12 more
doaj   +1 more source

Inactivation of rickettsiae [PDF]

open access: yesEuropean Journal of Microbiology and Immunology, 2013
A reliable and complete inactivation is an indispensable premise for any concentration of rickettsiae or for the development of diagnostic strategies based on their antigens. This study deals with the testing of methods to inactivate rickettsiae. Rickettsia honei was used as a model organism.
Hagen, Frickmann, Gerhard, Dobler
openaire   +2 more sources

Inactivation of Caliciviruses [PDF]

open access: yesApplied and Environmental Microbiology, 2004
ABSTRACT The viruses most commonly associated with food- and waterborne outbreaks of gastroenteritis are the noroviruses. The lack of a culture method for noroviruses warrants the use of cultivable model viruses to gain more insight on their transmission routes and inactivation methods. We studied the inactivation of the reported
Erwin, Duizer   +5 more
openaire   +2 more sources

A COMBINED INACTIVATED FREEZE DRIED VACCINE FOR ROTA AND CORONA VIRUSES [PDF]

open access: yesAssiut Veterinary Medical Journal, 1998
A combined inactivated Bovine Rota and Corona viruses vaccine was prepared on Madin Darby Bovine Kidney (MDBK), by use of Binary Ethyleneimine (BEI), as an inactivant.
Iman K.A. Kassem   +2 more
doaj   +1 more source

Optimization of RHDV type 1 and 2 inactivation modes

open access: yesВетеринария сегодня, 2021
The purpose of these studies was to optimize RHDV type 1 and 2 (RHDV1 and RHDV2) inactivation modes to use the obtained antigens in inactivated vaccines and diagnosticums.
E. D. Kunikova   +4 more
doaj   +1 more source

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