An effective inactivant based on singlet oxygen-mediated lipid oxidation implicates a new paradigm for broad-spectrum antivirals [PDF]
Redox Biology, 2020 Emerging viral pathogens cause substantial morbidity and pose a severe threat to health worldwide. However, a universal antiviral strategy for producing safe and immunogenic inactivated vaccines is lacking. Here, we report an antiviral strategy using the
Lei Zeng, Sheng-Li Ming, Guo-Li Li
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Inactivated vaccine against Aujeszky's disease [PDF]
Veterinary World, 2021 Background and Aim: The Aujeszky's disease, also known as Pseudorabies, remains one of the most problematic fulminant diseases in domestic animals, affecting the central nervous system.
Zhanat B. Kondibaeva +9 more
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Preparation of an Inactivated Peste des Petits Ruminants Vaccine and Its Comparative Immunogenicity Evaluation in an Animal Model [PDF]
Archives of Razi Institute, 2021 Peste des petits ruminants (PPR) is a highly contagious disease that is considered a major threat to the small livestock industry. Although vaccination via live-attenuated PPR vaccine is a main controlling strategy in the endemic area, during PPR ...
M Akbarian +4 more
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In vitro analysis of quercetin-like compounds from mistletoe Dendrophthoe pentandra (L.) Miq as a potential antiviral agent for Newcastle disease [version 8; peer review: 2 approved, 2 approved with reservations] [PDF]
F1000Research, 2023 Background Recent evidence suggests that some flavonoid compounds obtained from crude methanol extract of mistletoe leaves (Dendrophthoe pentandra L. Miq), also known as Benalu Duku (BD), have antimicrobial effects.
Lazuardi Mochamad +3 more
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Development and Testing of a Method for Validating Chemical Inactivation of Ebola Virus [PDF]
Viruses, 2018 Complete inactivation of infectious Ebola virus (EBOV) is required before a sample may be removed from a Biosafety Level 4 laboratory. The United States Federal Select Agent Program regulations require that procedures used to demonstrate chemical ...
Kendra J. Alfson, Anthony Griffiths
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Effects of binary ethyleneimine and formaldehyde inactivation methods on foot-and-mouth disease virus vaccine immune responses and kinetics [PDF]
Scientific ReportsFoot-and-mouth disease (FMD) is a highly contagious viral disease of livestock that has a significant economic impact on the country. The inactivated vaccine is the most widely used type of FMD vaccine, with the inactivation procedure being one of the ...
Wendyfraw Tsegaw Habtewold +10 more
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THE USE OF BINARY ETHYLENIMINE AND FORMALIN AS INACTIVANTS FOR PRODUCTION OF INACTIVATED NEWCASTLE DISEASE VACCINE [PDF]
Assiut Veterinary Medical Journal, 1996 The use of Binary Ethylenimine as inactivant for Newcastle virus give a promising result as it has no effect on the antiginecity of the virus when used or 0,03 M at the same time it had completely in a concentration of 0.01M reduced the virulence of the ...
SOAD, M. SOLIMAN +3 more
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Вопросы вирусологии, 2023 Introduction. Newcastle disease (ND) is classified as especially dangerous pathogen. Its primary source is an infected or recovered bird. The virus shedding begins just in a day after infection, and virus remains in the body for another 2-4 months after ...
Kuanish K. Jekebekov +12 more
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Inactivation of viral antigens for vaccine preparation with particular reference to the application of binary ethylenimine [PDF]
Vaccine, 1990 Bahnemann HG.
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A COMBINED INACTIVATED FREEZE DRIED VACCINE FOR ROTA AND CORONA VIRUSES [PDF]
Assiut Veterinary Medical Journal, 1998 A combined inactivated Bovine Rota and Corona viruses vaccine was prepared on Madin Darby Bovine Kidney (MDBK), by use of Binary Ethyleneimine (BEI), as an inactivant.
Iman K.A. Kassem +2 more
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