Results 11 to 20 of about 38,166 (233)

Application of Ion Exchange Chromatography in the Development of Technology to Obtain Inactivated Poliovirus Vaccine

Epidemiology and Vaccinal Prevention, 2022
Relevance. The production and quality control of any drugs are strictly regulated. In the case of antiviral vaccines, the requirements for their safety and protective activity are getting tougher every year.
A. Piniaeva, A. Kovpak, Y. Ivin, S. H. Sandzhieva, A. Shishova, I. O. Tсelykh, V. E. Vasilenko, K. V. Kaa, Zh. H. Mazhed, Y. K. Khapchaev, A. Siniugina, A. Ishmukhametov   +11 more
semanticscholar   +3 more sources

Analysis of a Sabin-Strain Inactivated Poliovirus Vaccine Response to a Circulating Type 2 Vaccine-Derived Poliovirus Event in Sichuan Province, China 2019-2021.

JAMA Netw Open, 2023
Key Points Question Can the Sabin-strain of the inactivated poliovirus vaccine (IPV) be used in response to a circulating type 2 vaccine-derived poliovirus (VDPV2) event?
Yang H, Qi Q, Zhang Y, Wen N, Cao L, Liu Y, Fan C, Yan D, Zhu X, Hao L, Zhu S, Ma Q, Liu J, Ma C, Nan L, Chen Y, Ma X, Chen N, Deng K, Shao G, Ding X, An Z, Rodewald LE, Li X, Wang D, Zhu H, Wang H, Feng Z, Xu W, Zhou J, Yin Z, China cVDPV2 Response Experts Group.   +31 more
europepmc   +2 more sources

Fecal Shedding of 2 Novel Live Attenuated Oral Poliovirus Type 2 Vaccine Candidates by Healthy Infants Administered Bivalent Oral Poliovirus Vaccine/Inactivated Poliovirus Vaccine: 2 Randomized Clinical Trials. [PDF]

J Infect Dis, 2022
Background Primary intestinal immunity through viral replication of live oral vaccine is key to interrupt poliovirus transmission. We assessed viral fecal shedding from infants administered Sabin monovalent poliovirus type 2 vaccine (mOPV2) or low and ...
Gast C, Bandyopadhyay AS, Sáez-Llorens X, De Leon T, DeAntonio R, Jimeno J, Aguirre G, McDuffie LM, Coffee E, Mathis DL, Oberste MS, Weldon WC, Konopka-Anstadt JL, Modlin J, Bachtiar NS, Fix A, Konz J, Clemens R, Costa Clemens SA, Rüttimann R.   +19 more
europepmc   +2 more sources

Surveillance of adverse events following the introduction of inactivated poliovirus vaccine made from Sabin strains (sIPV) to the Chinese EPI and a comparison with adverse events following inactivated poliovirus vaccine made from wild strains (wIPV) in Jiangsu, China. [PDF]

Hum Vaccin Immunother, 2021
One dose of inactivated poliovirus vaccine (IPV) was introduced into the Chinese Expanded Program on Immunization (EPI) in 2016. IPV made from Sabin strains (sIPV) was newly licensed in China and its safety has been concerned.
Kang G, Tang F, Wang Z, Hu R, Yu J, Gao J.   +5 more
europepmc   +2 more sources

One-Year Decline of Poliovirus Antibodies Following Fractional-Dose Inactivated Poliovirus Vaccine. [PDF]

J Infect Dis, 2021
BACKGROUND Fractional dose (1/5th of full intramuscular dose) of inactivated poliovirus-vaccine administered intradermally (fIPV) is used as IPV dose-sparing strategy. We compared the rate of decline of poliovirus antibodies (PVA) in recipients of either
Saleem AF, Mach O, Yousafzai MT, Kazi Z, Baig A, Sajid M, Jeyaseelan V, Sutter RW, Zaidi AKM.   +8 more
europepmc   +2 more sources

Effect of Inactivated Poliovirus Vaccine Campaigns, Pakistan, 2014–2017 [PDF]

Emerging Infectious Diseases, 2018
Pakistan began using inactivated poliovirus vaccine alongside oral vaccine in mass campaigns to accelerate eradication of wild-type poliovirus in 2014.
Nicholas C. Grassly, Mufti Zubair Wadood, Rana M. Safdar, Abdirahman Sheikh Mahamud, Roland W. Sutter   +4 more
doaj   +2 more sources

A Randomized Phase 4 Study of Immunogenicity and Safety After Monovalent Oral Type 2 Sabin Poliovirus Vaccine Challenge in Children Vaccinated with Inactivated Poliovirus Vaccine in Lithuania. [PDF]

J Infect Dis, 2021
Background Understanding immunogenicity and safety of monovalent type 2 oral poliovirus vaccine (mOPV2) in inactivated poliovirus vaccine (IPV)–immunized children is of major importance in informing global policy to control circulating vaccine-derived ...
Bandyopadhyay AS, Gast C, Brickley EB, Rüttimann R, Clemens R, Oberste MS, Weldon WC, Ackerman ME, Connor RI, Wieland-Alter WF, Wright P, Usonis V.   +11 more
europepmc   +2 more sources

Safety and immunogenicity of a new Sabin inactivated poliovirus vaccine candidate produced on the PER.C6® cell-line: a phase 1 randomized controlled trial in adults. [PDF]

Hum Vaccin Immunother, 2021
This first-in-human study (NCT03032588), conducted in Belgium, evaluated a new inactivated poliovirus vaccines (IPV) candidate based on Sabin poliovirus strains grown on the high-yield PER.C6® cell line.
Leroux-Roels I, Leroux-Roels G, Shukarev G, Schuitemaker H, Cahill C, de Rooij R, Struijs M, van Zeeburg H, Jacquet JM.   +8 more
europepmc   +2 more sources

Experimental Approaches to the Development of Inactivated Poliovirus Vaccine Based on Sabin Strains

Эпидемиология и вакцинопрофилактика, 2016
The results of development of experimental series of inactivated poliovirus vaccine based on Sabin strains (s-IPV) using conventional modern techniques are presented.
A. P. Ivanov, T. D. Klebleeva, O. E. Ivanova, E. G. Ipatova, L. V. Gmyl, A. A. Ishmuhametov   +5 more
doaj   +3 more sources

Inactivated Poliovirus Vaccine [PDF]

Definitions, 2020
A vaccine consisting of inactivated poliovirus (IPV) types 1,2 and 3, with active immunizing activity against poliomyelitis. Upon intramuscular vaccination, inactivated poliovirus vaccine (IPV) activates the immune system to develop antibodies against ...
openaire   +2 more sources