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The Critical Role of GALNTs‐Regulated O‐GalNAc Glycosylation in Cancer Malignancy
The GALNT family initiates mucin‐type O‐GalNAc glycosylation in the Golgi apparatus and how regulatory mechanisms, including GALNT relocalization and microRNA control, modulate this process. Dysregulated O‐GalNAc glycosylation alters key cellular behaviors and promotes cancer malignancy, highlighting its relevance to tumor progression as well as its ...
Jiahao Liu +7 more
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A SAR study led to the identification of new 2‐phenylquinoline‐based derivatives that exhibit anti‐Severe Acute Respiratory Syndrome Coronavirus‐2 (SARS‐CoV‐2) activity by acting as ATP‐competitive inhibitors of nonstructural protein 13 (nsp13) helicase.
Giada Cernicchi +24 more
wiley +1 more source
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An inactivated vaccine against ringworm
Comparative Immunology, Microbiology and Infectious Diseases, 1992A new vaccine against ringworm, containing the inactivated Trichophyton verrucosum strain, was assessed on guinea pigs and calves under experimental conditions and on three herds of cattle under natural conditions. The vaccine elicited a distinct immune response of the cellular type.
K, Wawrzkiewicz, J, Wawrzkiewicz
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Inactivated virosome hepatitis A vaccine
The Lancet, 1994Immunopotentiating reconstituted influenza virosomes (IRIV) are efficient carrier systems for small virion particles such as hepatitis A virus (HAV). We evaluated immunogenicity and tolerability of an IRIV-HAV vaccine and the effectiveness of a booster by immunising 104 healthy HAV seronegative volunteers. A single dose was highly immunogenic, since 98%
L, Loutan +3 more
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Inactivated Poliovirus Vaccine
Human Vaccines, 2007Subhash C, Arya, Nirmala, Agarwal
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Polio Vaccines— Live or Inactivated?
JAMA: The Journal of the American Medical Association, 1966To the Editor:— Two excellent vaccines are in current use to protect against poliomyelitis. Inactivated poliomyelitis vaccine (IPV) developed by Salk has been widely used since 1955. IPV is characterized by complete safety, imperfect immunizing power, and the need for percutaneous administration.
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Inactivated and Adjuvanted Influenza Vaccines
2014Inactivated influenza vaccines are produced every year to fight against the seasonal epidemics of influenza. Despite the nonoptimal coverage, even in subjects at risk like the elderly, pregnant women, etc., these vaccines significantly reduce the burden of mortality and morbidity linked to the influenza infection.
Giuseppe, Del Giudice, Rino, Rappuoli
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