Results 231 to 240 of about 132,203 (305)
Abstract Background Feline coronavirus (FCoV) causes inapparent to progressive fatal feline infectious peritonitis (FIP) in domestic and wild cats, which affects multiple‐organ systems. Methods We investigated three clinically sick cats using different laboratory and molecular tests to diagnose and confirm FCoV and propagate the virus in Vero cell ...
Eaftekhar Ahmed Rana +5 more
wiley +1 more source
Yellow Fever Vaccine Inactivation Studies
H W, BURRUSS, M V, HARGETT
openaire +2 more sources
Activation of the Lectin Pathway Drives Persistent Complement Dysregulation in Long COVID
The complement cascade, a series of blood proteins that assists in the recognition and neutralisation of pathogens, either independently or in conjunction with antibodies, is persistently activated in patients with long COVID. We found that blood plasma samples from patients with long COVID contained elevated concentrations of the mannan‐binding lectin‐
Samuel B. K. Keat +14 more
wiley +1 more source
ABSTRACT Ovarian Cancer (OC), the deadliest gynecological malignancy, poses a major therapeutic challenge in advanced stages owing to its high recurrence rate and metastatic potential. In this regard, it is noteworthy that immunotherapy has recently gained significant attention in OC treatment, a phenomenon attributable to notable advances in over‐the ...
Liying Wang +4 more
wiley +1 more source
Repurpose an FDA‐Approved Antibody Using DARPin‐Scaffolded Bridge Protein
The cell line and scalable upstream/downstream process development needed for every new monoclonal antibody are both highly expensive and time‐consuming, significantly increasing the cost of new antibody therapeutics. By contrast, the production of many synthetic binders can be accomplished rapidly and with lower production costs.
Michael Woolley +4 more
wiley +1 more source
Vaccination Against Tuberculosis: Revamping BCG by Molecular Genetics Guided by Immunology
Kaufmann, S.
core +1 more source
Isocitrate Dehydrogenase Mutations in Cancer: From Bench to Bedside Applications
Mutant isocitrate dehydrogenase affects multiple cancer types. Alterations in IDH1 and IDH2 result in abnormal enzyme activity, leading to the overproduction of D‐2‐hydroxyglutarate (D‐2HG). This metabolite disrupts cellular metabolism and epigenetic regulation, driving cancer initiation, progression, and metastasis.
Yuhan Fang +6 more
wiley +1 more source
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi +6 more
wiley +1 more source
Ovine enzootic abortion, caused by Chlamydia abortus, leads to significant reproductive losses in sheep. This study found 12.6% of 781 sheep in Montana tested positive for antibodies with differences by breed, flock and herding status. ABSTRACT Background Ovine enzootic abortion (OEA) is a reproductive disease in domestic sheep characterized by late ...
Avia J. Simmons +4 more
wiley +1 more source
Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines
Vox Sanguinis, EarlyView.
Pierre Tiberghien +4 more
wiley +1 more source

