Results 91 to 100 of about 8,524 (262)

Rare vasculitis types and obstetric and neonatal outcomes – A population‐based study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Vasculitis is an infrequent pathology among reproductive‐aged women. While data exists regarding pregnancy outcomes in the more common vasculitis subtypes, data is limited regarding these outcomes in rare vasculitis subtypes. We aimed to compare pregnancy and perinatal outcomes between women who suffered from rare types of vasculitis
Uri Amikam, Ahmad Badeghiesh, Haitham Baghlaf, Richard Brown, Michael H. Dahan   +4 more
wiley   +1 more source

Red flags to suspect inborn errors of immunity in patients with autoimmune diseases

Biomédica: revista del Instituto Nacional de Salud
Inborn errors of immunity are monogenic disorders that predispose patients to immune dysregulation, autoimmunity, and infection. Some autoimmune diseases, such as autoimmune cytopenias, systemic lupus erythematosus, and inflammatory bowel diseases, are ...
Natalia Vélez, Juliette De Ávila, Jaime Cortés, Nelson Barrero, Leosirlay Rojas, Juan Manuel Bello, Consuelo Romero-Sánchez   +6 more
doaj   +1 more source

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Unlocking life-threatening COVID-19 through two types of inborn errors of type I IFNs

The Journal of Clinical Investigation, 2023
Since 2003, rare inborn errors of human type I IFN immunity have been discovered, each underlying a few severe viral illnesses. Autoantibodies neutralizing type I IFNs due to rare inborn errors of autoimmune regulator (AIRE)–driven T cell tolerance were ...
Jean-Laurent Casanova, Mark S. Anderson
doaj   +1 more source

Lessons learned from the study of human inborn errors of innate immunity

, 2019
Innate immunity contributes to host defense through all cell types and relies on their shared germline genetic background, whereas adaptive immunity operates through only 3 main cell types, αβ T cells, γδ T cells, and B cells, and relies on their somatic
Bosch, Barbara, Bucciol, Giorgia, Moens, Leen, Bossuyt, Xavier, Casanova, Jean-Laurent, Meyts, Isabelle, Puel, Anne   +6 more
core   +1 more source

Utility of a Combined Diagnostic and Severity Scoring System Based on Complete Blood Count and Derived Immune‐Inflammatory Indicators in Children With Mycoplasma pneumoniae Pneumonia

Journal of Clinical Laboratory Analysis, EarlyView.
This study developed a simple, low‐cost scoring system using routine complete blood count (CBC) and derived immune‐inflammatory indicators (LYM%, PLT, PCT, and PLT × LYM) for early diagnosis of Mycoplasma pneumoniae pneumonia (MPP) in 1662 children. Age‐stratified analysis confirmed that key indicators remained significantly higher in the pneumonia ...
Quan Liu, Li Wei, Liang Wang, Xing‐Mei Zhu, Hai‐Feng Wang, Ling Ge   +5 more
wiley   +1 more source

Inborn errors of immunity in paediatric neurology [PDF]

Inborn errors of immunity has become a rapidly evolving medical field, with nearly 500 conditions; as a result, the sheer volume of information can be overwhelming.
Smuts, Izelle, Human, Freda P.
core   +1 more source

A Framework to Establish Diet and Nutrition Competencies for Oral Health Care Education

Journal of Dental Education, EarlyView.
ABSTRACT Objective: To prevent and manage oral disease, oral health care practitioners (OHCPs) must provide dietary counseling based on nutrition science. OHCPs are often ill‐equipped to provide such counseling due to fragmented and inadequate dietary education, which is typically attributed to limited curricular time or appropriately qualified faculty.
Teresa A. Marshall, Michael Crowe, Riva Touger‐Decker   +2 more
wiley   +1 more source

A multicenter, controlled, randomized trial of home‐applied dual‐light photodynamic therapy in stage I to III periodontitis (LumoNorth2022 study)

Journal of Periodontology, EarlyView.
Abstract Background Periodontitis is a widespread, chronic infection‐triggered inflammatory condition in which professional supportive periodontal care (SPC) and daily oral hygiene form the backbone to reduce the disease activity. Light‐based treatments have shown promising antibacterial effects, but their potential for routine home use has not been ...
Paula Tegelberg, Meeri Ojala, Merja Ylipalosaari, Jori Lindroth, Anna Maria Heikkinen, Hanna Lähteenmäki, Saila Pakarinen, Ismo T. Räisänen, Timo Sorsa, Tommi Pätilä   +9 more
wiley   +1 more source

“It’s a Godsend”: Parental experiences of genomic testing for paediatric inborn errors of immunity

Genomic testing has become essential to diagnosing and managing paediatric inborn errors of immunity (IEI), necessitating the development of mainstream models of care to facilitate optimal delivery of testing.
Melo, Mariana, Yanes, Tatiane, Sgro, Christopher, McNaughton, Peter, Peake, Jane, DeBortoli, Emily, McInerney-Leo, Aideen, Sullivan, Anna, Clark, Amy, Clinch, Tenielle, Pinzon-Charry, Alberto, Blancoe, Marisa   +11 more
core   +1 more source