Results 111 to 120 of about 7,759 (229)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Cerebral ischaemia is a leading cause of death in older adults and imposes a substantial global economic burden. Recent studies indicate that inhibiting the Gαs‐coupled EP2 receptor reduces ischaemic brain injury by modulating neuroinflammation.
Zhen Jin +7 more
wiley +1 more source
Expanding the Biochemical Phenotype of ReNU Syndrome: A Case Report
Clinical Genetics, EarlyView.This report detailed the clinical findings and the biochemical phenotype of a 3‐year‐old girl with ReNU syndrome. Circulating biomarkers and a muscle biopsy s uggested mild mitochondrial abnormalities. Severe plasmalogen deficiency was also observed, comparable to defects of peroxisomal plasmalogen biosynthesis.
Irene De Biase +4 more
wiley +1 more source
Biomédica: revista del Instituto Nacional de SaludIntroduction. Inborn errors of immunity is a diverse group of rare diseases caused by over 400 genetic mutations affecting the immune system and increasing infection susceptibility, autoimmunity, and malignancy.
Diego Medina +6 more
doaj +1 more source
Stratum Corneum Biomarkers for Differentiating Irritant and Allergic Contact Dermatitis
Contact Dermatitis, EarlyView.From 126 patients with irritant or allergic contact dermatitis of the hands, stratum corneum tape strips from patch test sites and lesional hand skin were collected and analysed for barrier and immune biomarkers, and machine learning models were trained to separate ICD from ACD.
F. L. de Boer +10 more
wiley +1 more source
RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms
The FEBS Journal, EarlyView.RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon +4 more
wiley +1 more source
Algorithms in Allergy: Diagnosis of Hypereosinophilic Syndromes, 2026 Update
Allergy, EarlyView.
Guillaume Lefèvre +5 more
wiley +1 more source
Cutaneous lymphomas – an update
Histopathology, EarlyView.Primary cutaneous lymphomas and lymphoproliferative disorders are defined by integrated clinical, histopathological, immunophenotypic and genetic features as diagnostic criteria also in the 5th edition of the WHO classification of haematolymphoid tumors.
Werner Kempf, Christina Mitteldorf
wiley +1 more source
International Journal of Dental Hygiene, EarlyView.ABSTRACT Objectives This study aimed to investigate the relationship between functional independence, oral hygiene habits and periodontal status in patients with Down syndrome (DS). Methods A cross‐sectional observational study was conducted with 49 patients with Down Syndrome. Sociodemographic data, oral hygiene habits and functional independence were
Joana Albuquerque Bastos de Sousa +6 more
wiley +1 more source