Results 151 to 160 of about 7,759 (229)

The BTB/POZ‐MATH Protein ZmBPM1 Interacts With Autophagy‐related Protein ZmATG6 and Modulates the NLR Protein Rp1‐D21‐Mediated Defense Response in Maize

Advanced Science, Volume 13, Issue 61, 3 November 2026.
The maize BTB/POZ‐MATH (BPM) protein ZmBPM1 interacts with autophagy‐related protein ZmATG6 to relocate the NLR protein Rp1‐D21 from the nucleo‐cytoplasmic compartment into autophagosome‐like puncta, leading to autophagy‐mediated turnover and suppressing the hypersensitive response.
Chang‐Xiao Tang, Tong‐Tong Liu, Qi‐Dong Ge, Xiao‐Ying Liu, Wanxiao Wang, Yang Sun, Yanfei Liu, Faqiang Li, Guan‐Feng Wang   +8 more
wiley   +1 more source

In a nutshell: Pandora's Box-B-cell lymphoproliferation masking inborn errors of immunity. [PDF]

Br J Haematol
Sánchez-Ramón S, Bussel JB.
europepmc   +1 more source

Inflammation and Oxidative Damage in Fatty Acids Oxidation Disorders

Cell Biochemistry and Function, Volume 44, Issue 11, November 2026.
ABSTRACT Deficiencies in enzymes and transporters involved in mitochondrial fatty acid beta oxidation results in the accumulation of fatty acids, a condition known as fatty acid oxidation disorders (FAODs). Therefore, the present study aimed to evaluate the oxidative and inflammatory profiles of treated patients with FAODs, comparing those receiving ...
Stefani Altenhofen, Luísa Tedesco, Franciele Fátima Lopes, Marina Acosta, Ângela Sitta, Daniella de Moura Coelho, Bianca Gomes dos Reis, Luiza Wailer, Debora Tonelotto, Ana Kalise Bottcher, Moacir Wajner, Carmen Regla Vargas   +11 more
wiley   +1 more source

GATA2 Deficiency Presenting With a WHIM‐Like Phenotype and Subsequent Development of Monosomy 7‐Associated Myelodysplastic Syndrome in an Adolescent Female: A Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT We report an 18‐year‐old female with GATA2 deficiency presenting with a WHIM‐like phenotype, including pancytopenia, monocytopenia, CD19+ B‐cell depletion, sensorineural hearing loss, and cutaneous warts. Subsequent cytogenetic evaluation revealed monosomy 7 and 7q22 deletion, with bone marrow progression to MDS.
Aziz Eghbali, Meshkat Poortavakol, Hamideh Sadat Mirmohammadi   +2 more
wiley   +1 more source

Rare vasculitis types and obstetric and neonatal outcomes – A population‐based study

International Journal of Gynecology &Obstetrics, Volume 175, Issue 2, Page 877-884, November 2026.
Abstract Objective Vasculitis is an infrequent pathology among reproductive‐aged women. While data exists regarding pregnancy outcomes in the more common vasculitis subtypes, data is limited regarding these outcomes in rare vasculitis subtypes. We aimed to compare pregnancy and perinatal outcomes between women who suffered from rare types of vasculitis
Uri Amikam, Ahmad Badeghiesh, Haitham Baghlaf, Richard Brown, Michael H. Dahan   +4 more
wiley   +1 more source

Betaine Attenuates Cuprizone‐Induced Cortical Demyelination: The Role of the WNT4/mTOR Signalling Pathway in Regulating Astrogliosis and Synaptic Integrity

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 11, November 2026.
Betaine helps to restore the dysfunctional communication between oxidative stress and inflammation, and it also improves demyelination in cuprizone‐induced demyelinating disease within the cerebral cortex. ABSTRACT Cortical grey matter pathology manifests early demyelinating diseases and is a primary driver of permanent neurological impairment.
Yara M. Said, Heba‐Tallah Abd Elrahim Abd Elkader, Gihad Jamal Bekheet, Sherine Abdel Salam, Amina E. Essawy   +4 more
wiley   +1 more source

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno, Laura Cinque, Viviana Cetrangolo, Chiara De Leonibus   +3 more
wiley   +1 more source

Nucleic Acid Therapeutics in Rare Disease: From Precision Medicine to Programmable Platforms

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Nucleic acid therapeutics (NATs), including antisense oligonucleotides (ASOs), small interfering RNAs (siRNAs), messenger RNA (mRNA) therapeutics and programmable editing technologies, are reshaping the therapeutic landscape for inherited metabolic and genetic disease.
Tomasz Z. Tomkiewicz, Siyamini Sivananthan, Paul Gissen, Haiyan Zhou   +3 more
wiley   +1 more source

Hypocortisolaemia with gastrointestinal haemorrhage in a young cat

Veterinary Record Case Reports, Volume 14, Issue 4, November 2026.
Abstract An 8‐month‐old, female, spayed domestic shorthair presented with a 1‐week history of lethargy and anorexia. On admission, the cat had severe hypoglycaemia, and hypovolaemic and distributive shock were suspected. Mucosal defects identified by ultrasonography were suggestive of gastrointestinal ulceration.
Victoria J. Skinner, Bronwyn Zimmerman, Ivayla D. Yozova   +2 more
wiley   +1 more source

Genome Aging in Women: Hematopoietic Loss of X Chromosome as An Exemplar

Aging Cell, Volume 25, Issue 11, November 2026.
As studies at the intersection of genetics and aging are rapidly advancing, genome aging provides a novel mechanism by which aging phenotypes occur. In this Review, the authors examine the rise, expansion, and the consequences of X chromosome loss in female blood cells.
Xihan Guo, Xueqin Dai
wiley   +1 more source