Results 151 to 160 of about 7,049 (225)

The ageing holobiont: crosstalk between telomere dynamics, oxidative stress and the gut microbiome

Biological Reviews, Volume 101, Issue 4, Page 1877-1903, August 2026.
ABSTRACT The gut tissue is at the frontline of early onset of ageing. It exhibits high cell turnover rates and rapid telomere shortening, which can have systemic effects on the developing or senescing organism. We conducted a literature review of studies on the crosstalk between telomere length dynamics, telomerase activity, oxidative stress, and gut ...
Michael L. Pepke, Søren B. Hansen, Morten T. Limborg   +2 more
wiley   +1 more source

Environment and Host Genetics Drive Infection Outcomes in a Butterfly Host, but Do Not Interact With Each Other

Ecology and Evolution, Volume 16, Issue 8, August 2026.
This study examined how host genetics and larval food plant environment influence parasite infection outcomes in monarch butterflies (Danaus plexippus) infected with the protozoan Ophryocystis elektroscirrha. We tested for genotype × environment interactions on infection status, infection burden, lifespan, and wing size.
Ania A. Majewska, Grace Chlebove, Jacobus C. de Roode   +2 more
wiley   +1 more source

Overview of next-generation sequencing to the molecular diagnosis of inborn errors of immunity in Brazil: a systematic review. [PDF]

Front Immunol
Dos Santos-Bueno FV, Morgado ES, Agonigi BNDS, Lopes MRG, Pinheiro MO, da Silva LL, Salú MDS, Faccion RS, de Vasconcelos ZFM.   +8 more
europepmc   +1 more source

Preclinical 1H MRS Study of a Porcine Model Shows Evidence and Mechanisms for Acute Neuronal Injury in Neonatal Cardiopulmonary Bypass (CPB) Surgery

Magnetic Resonance in Medicine, Volume 96, Issue 2, Page 557-567, August 2026.
ABSTRACT Purpose Congenital heart disease affects 1% of US births, with some infants requiring cardiothoracic surgery under cardiopulmonary bypass (CPB). Optimal surgical parameters to minimize neuronal injury are unknown. We used serial 1H MRS in a neonatal CPB porcine model to assess acute neuronal damage and associated injury mechanisms.
Aaron Omon, Meng Gu, Ralph Hurd, Kirk Riemer, Frank Hanley, Daniel Spielman   +5 more
wiley   +1 more source

Gastroenterological disorders in inborn errors of immunity. Part 2 A. Overview of selected diseases. [PDF]

Prz Gastroenterol
Napiórkowska-Baran K, Treichel P, Koperska K, Kudrej O, Mućka N, Rajewska A, Wawrzeńczyk A, Bartuzi Z.   +7 more
europepmc   +1 more source

Cross Sectional Study of Prenatal Diagnosis Uptake Among Individuals With Genetic Conditions

Prenatal Diagnosis, Volume 46, Issue 9, Page 1374-1384, August 2026.
ABSTRACT Objective Prenatal diagnostic genetic testing allows for early identification of significant fetal conditions and enables informed decision‐making regarding management options. The aim of this study was to assess prenatal testing practice among individuals with genetic conditions.
Ebunoluwa Ojo, Roni Zemet, Allyson Nevins, Katherine Abraham, April D. Adams   +4 more
wiley   +1 more source

Opinion: Why paediatric rheumatologists need to understand inborn errors of immunity. [PDF]

Front Pediatr
Abinun M, Owens S.
europepmc   +1 more source

Effects of Bifidobacterium animalis Subsp. Lactis CP‐9 on Gut Microbiota and Immune Functions in Healthy Infants

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
This study evaluated the 3‐month safety and tolerability of the probiotic CP‐9 in healthy infants aged 6 to 36 months. The research confirmed that, under the conditions of this study, CP‐9 can safely enrich specific beneficial bacterium in the gut without any obvious short‐term safety signal. ABSTRACT Infancy represents a critical period for growth and
Liujing Zhang, Xueke Song, Keming Zhang, Xiaoshuang Xu, Xinmei Guo, Wei Li, Xiaoling Zeng, Yingguang Xie, Liwei Nie, Li Zhao, Xuelu Dai, Jing Sun, Jiai Yan, Yiran Liu, Feng Zhang, Zhiping Sun   +15 more
wiley   +1 more source

Excluded GM-specific IgG Subclass Genes in Health and Disease - Inborn Errors of Immunity. [PDF]

J Clin Immunol
Oxelius VA.
europepmc   +1 more source

Maternal High Fat Diet and Acute Viral Mimic Exposure Impact Placental Inflammation, Lipid Peroxidation and Cellular Proliferation‐to‐Death Ratio Across Mouse Pregnancy

American Journal of Reproductive Immunology, Volume 96, Issue 2, August 2026.
Abstract Problem Maternal obesity and viral infection induce placental inflammation, but how their co‐exposure influence fetoplacental development remains unclear. We hypothesised that maternal high fat (HF) diet and viral infection would independently induce placental inflammation and lipid peroxidation, reduce antioxidant defence, and cellular ...
Thaina Ferraz, Lucas Cardoso, Sadra Mohammadkhani, Enrrico Bloise, Kristin L. Connor   +4 more
wiley   +1 more source