Results 161 to 170 of about 7,759 (229)
Exploring the Role of Transposable Elements to Sex Gap in Longevity in Three Drosophila Species
Sex differences in Drosophila lifespan are o1en linked to Y‐chromosome TE content. Although TE expression increases with age and a higher number of upregulated TE copies were found in older males, this did not correlate with reduced lifespan. Moreover, Y chromosome replacement affects male longevity and gene and TE expression in D.
Miriam Merenciano +12 more
wiley +1 more source
Health impacts of public pawnshops in Industrialising Tokyo
Abstract This study examines whether expanded credit access through low‐interest small loans relaxed liquidity constraints among poor households and improved early‐life health in industrialising Tokyo. Using ward‐level panel data for 1927–1935, this study shows that public pawnshop lending was associated with 4% and 5% reductions in infant and foetal ...
Tatsuki Inoue
wiley +1 more source
Abstract Coats disease diagnosed in adulthood is a rare idiopathic retinal telangiectatic vasculopathy that may differ in phenotype from childhood‐diagnosed cases. This systematic review synthesizes current evidence to characterize its clinical spectrum, imaging features, treatment outcomes and underlying mechanisms, with a focus on immunovascular ...
Catarina Francisco +2 more
wiley +1 more source
Immune System Development—Pro Tips for Paediatricians
ABSTRACT There are many misconceptions about the immune system in children, its impact on infectious disease susceptibility and its role in the rapidly increasing rates of immune mediated diseases in industrialized societies. In this mini review, I will discuss common believes and the data supporting or countering such believes, with a focus on ...
Petter Brodin
wiley +1 more source
Malignancies in patients with inborn errors of immunity: insights from 20-years of clinical experience in Qatar. [PDF]
Khalil SM +9 more
europepmc +1 more source
In this large multicenter cohort of patients with ataxia–telangiectasia, non‐neurological manifestations frequently preceded neurological features, with respiratory infections representing a major clinical burden. Immunoglobulin abnormalities and class‐switch recombination defects were common and associated with increased clinical morbidity, while ...
Saba Fekrvand +32 more
wiley +1 more source
Designing an integrated data model for prospective genotype-phenotype in inborn errors of immunity research. [PDF]
Ahmed M, Bousfiha AA, Almarzooqi F.
europepmc +1 more source
ABSTRACT Background and Aims Primary sclerosing cholangitis (PSC) is a rare, progressive cholangiopathy for which diagnosis remains challenging because of the absence of disease‐specific markers and the presence of secondary causes of sclerosing cholangitis (SSC) that closely mimic its clinical presentation. Diagnostic uncertainty can delay appropriate
Miki Scaravaglio +20 more
wiley +1 more source
Tuberculosis screening in adult patients with inborn errors of immunity: a single-center cohort study. [PDF]
Korkmaz P +16 more
europepmc +1 more source
A MUC13 Variant Enhances Intestinal Ferric Iron Absorption in Unexplained Hyperferritinemia
ABSTRACT Background & Aims Hyperferritinemia frequently remains unexplained despite comprehensive evaluation. We conducted a sequencing‐based exome association study to identify genetic variants associated with plasma ferritin levels in patients with unexplained hyperferritinemia.
Jonas Callet +22 more
wiley +1 more source

