Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping [PDF]
Frontiers in Genetics, 2019 The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman +4 more
doaj +4 more sources
A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. [PDF]
PLoS ONE, 2009 Glyoxalase 1 (Glo1) has been implicated in anxiety-like behavior in mice and in multiple psychiatric diseases in humans. We used mouse Affymetrix exon arrays to detect copy number variants (CNV) among inbred mouse strains and thereby identified a ...
Richard Williams +13 more
doaj +5 more sources
Inbreeding Ratio and Genetic Relationships among Strains of the Western Clawed Frog, Xenopus tropicalis. [PDF]
PLoS ONE, 2015 The Western clawed frog, Xenopus tropicalis, is a highly promising model amphibian, especially in developmental and physiological research, and as a tool for understanding disease.
Takeshi Igawa +10 more
doaj +10 more sources
Whole Genome Sequence of Two Wild-Derived Mus musculus domesticus Inbred Strains, LEWES/EiJ and ZALENDE/EiJ, with Different Diploid Numbers [PDF]
G3: Genes, Genomes, Genetics, 2016 Wild-derived mouse inbred strains are becoming increasingly popular for complex traits analysis, evolutionary studies, and systems genetics. Here, we report the whole-genome sequencing of two wild-derived mouse inbred strains, LEWES/EiJ and ZALENDE/EiJ ...
Andrew P. Morgan +6 more
doaj +2 more sources
The mouse antibody heavy chain repertoire is germline-focused and highly variable between inbred strains. [PDF]
Philos Trans R Soc Lond B Biol Sci, 2015 Collins AM +4 more
europepmc +3 more sources
Scientific Reports, 2023 Salmonella enterica serovar Typhi is the causative agent of typhoid fever restricted to humans and does not replicate in commonly used inbred mice. Genetic variation in humans is far greater and more complex than that in a single inbred strain of mice ...
Kishore R. Alugupalli +11 more
doaj +1 more source
The Effect of Population Structure on Murine Genome-Wide Association Studies
Frontiers in Genetics, 2021 The ability to use genome-wide association studies (GWAS) for genetic discovery depends upon our ability to distinguish true causative from false positive association signals.
Meiyue Wang +7 more
doaj +1 more source
In silico candidate variant and gene identification using inbred mouse strains [PDF]
PeerJ, 2021 Mice are the most widely used animal model to study genotype to phenotype relationships. Inbred mice are genetically identical, which eliminates genetic heterogeneity and makes them particularly useful for genetic studies.
Matthias Munz +4 more
doaj +2 more sources
A general Bayesian approach to analyzing diallel crosses of inbred strains. [PDF]
Genetics, 2012 Lenarcic AB +3 more
europepmc +3 more sources
The Mouse Universal Genotyping Array: From Substrains to Subspecies
G3: Genes, Genomes, Genetics, 2016 Genotyping microarrays are an important resource for genetic mapping, population genetics, and monitoring of the genetic integrity of laboratory stocks.
Andrew P. Morgan +22 more
doaj +1 more source