Results 101 to 110 of about 171,279 (298)

In vivo microscopic voxel-based morphometry with a brain template to characterize strain-specific structures in the mouse brain

Scientific Reports, 2017
Hundreds of inbred mouse strains are established for use in a broad spectrum of basic research fields, including genetics, neuroscience, immunology, and cancer.
Keigo Hikishima, Yuji Komaki, Fumiko Seki, Yasuyuki Ohnishi, Hirotaka J. Okano, Hideyuki Okano   +5 more
doaj   +1 more source

Variation in histone configurations correlates with gene expression across nine inbred strains of mice. [PDF]

Genome Res, 2023
Tyler AL, Spruce C, Kursawe R, Haber A, Ball RL, Pitman WA, Fine AD, Raghupathy N, Walker M, Philip VM, Baker CL, Mahoney JM, Churchill GA, Trowbridge JJ, Stitzel ML, Paigen K, Petkov PM, Carter GW.   +17 more
europepmc   +1 more source

CRISPR/Cas9‐based white pupae mutant lines in Bactrocera spp. for sterile insect technique applications

Insect Science, EarlyView.
Bactrocera fruit flies are significant horticultural pests that cause major economic losses. A “neoclassical approach” incorporating genome editing via CRISPR/Cas9 to develop genetic sexing strains (GSS) could render the sterile insect technique (SIT) against these pests more efficient and cost‐effective.
Chrysanthi Ioannidou, Maria‐Eleni Gregoriou, Marc F. Schetelig, Elena Drosopoulou, Kostas D. Mathiopoulos, Kostas Bourtzis   +5 more
wiley   +1 more source

Genetic heterogeneity of plasma lipoproteins in the mouse: control of low density lipoprotein particle sizes by genetic factors.

Journal of Lipid Research, 1990
In order to assess the genetic control of sizes and concentrations of mouse plasma low density (LDL) and high density lipoproteins (HDL), we used gel permeation fast protein liquid chromatography (FPLC) and nondenaturing gradient polyacrylamide gel ...
S Jiao, T G Cole, RT Kitchens, B Pfleger, G Schonfeld   +4 more
doaj   +1 more source

Effects of genetics and sex on adolescent behaviors following neonatal ethanol exposure in BXD recombinant inbred strains. [PDF]

Front Neurosci, 2023
Baker JA, Mulligan MK, Hamre KM.
europepmc   +1 more source

Neoclassical development of genetic sexing strains for insect pest and disease vector control

Insect Science, EarlyView.
The sterile insect technique has been effectively used for decades, and an important component is the availability of sex separation systems, in particular genetic sexing strains. Classical approaches, such as irradiation‐induced chromosomal translocations, have yielded stable strains for species like the Mediterranean fruit fly.
Giovanni Petrucci, Maria‐Eleni Gregoriou, Philippos Aris Papathanos, Marc F. Schetelig, Zhijian Tu, Kostas Bourtzis   +5 more
wiley   +1 more source

Intraocular pressure in inbred mouse strains

Investigative ophthalmology & visual science, 1997
PURPOSE: To develop a protocol to measure the intraocular pressure (IOP) of living mice and to determine the IOP of genetically different mouse strains. METHODS: Eyes of anesthetized animals were cannulated with a very fine fluid-filled glass microneedle.
S W, John, J R, Hagaman, T E, MacTaggart, L, Peng, O, Smithes   +4 more
openaire   +2 more sources

In Silico Approaches and the Role of Ontologies in Aging Research [PDF]

, 2013
The 2013 Rostock Symposium on Systems Biology and Bioinformatics in Aging Research was again dedicated to dissecting the aging process using in silico means.
Busch, Hauke, Börries, Melanie, de Grey, Aubrey, Fuellen, Georg, Hahn, Udo, Hiller, Thomas, Hoeflich, Andreas, Jansen, Ludger, Janssens, Georges E., Kaleta, Christoph, Meinema, Anne C., Others, Schofield, Paul N., Schäuble, Sascha, Smith, Barry   +14 more
core  

Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population. [PDF]

G3 (Bethesda), 2023
Keele GR.
europepmc   +1 more source

Evidence of emerging transcriptome mediators of Alzheimer's disease in canine cognitive dysfunction

Brain Pathology, EarlyView.
Canine cognitive dysfunction (CCD) may be a promising model of Alzheimer's disease (AD). To assess AD‐related molecular signatures in CCD, we generated transcriptome data on dog cortex and plasma extracellular vesicles (EVs). CCD‐related transcriptome changes were similar to those in aging/AD humans and were detectable in EVs from the same animals ...
Shelby C. Osburn, Darby S. Easterday, Cali M. McEntee, Amanda S. Latham, Daniel S. Lark, Stephanie McGrath, Julie A. Moreno, Thomas J. LaRocca   +7 more
wiley   +1 more source