Results 101 to 110 of about 2,324,041 (334)
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza+4 more
wiley +1 more source
High-Resolution Maps of Mouse Reference Populations
Genetic reference panels are widely used to map complex, quantitative traits in model organisms. We have generated new high-resolution genetic maps of 259 mouse inbred strains from recombinant inbred strain panels (C57BL/6J × DBA/2J, ILS/IbgTejJ × ISS ...
Petr Simecek+11 more
doaj +1 more source
Absence seizures: Update on signaling mechanisms and networks
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Genetic analysis of cholesterol accumulation in inbred mice
Genetic linkage analysis in the laboratory mouse identified chromosomal regions containing genes that contribute to cholesterol accumulation in the liver and plasma.
Margrit Schwarz+3 more
doaj
Hundreds of inbred mouse strains are established for use in a broad spectrum of basic research fields, including genetics, neuroscience, immunology, and cancer.
Keigo Hikishima+5 more
doaj +1 more source
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers+10 more
wiley +1 more source
A Candidate Subspecies Discrimination System Involving a Vomeronasal Receptor Gene with Different Alleles Fixed in \u3ci\u3eM. m. domesticus\u3c/i\u3e and \u3ci\u3eM. m. musculus\u3c/i\u3e [PDF]
Assortative mating, a potentially efficient prezygotic reproductive barrier, may prevent loss of genetic potential by avoiding the production of unfit hybrids (i.e., because of hybrid infertility or hybrid breakdown) that occur at regions of secondary ...
Karn, Robert C.+2 more
core +1 more source
Cereal‐legume intercropping is a promising strategy for sustainable agroecosystems, leveraging the biological complementarities between plant species to reduce the need for inputs while enhancing field biodiversity. Here, we focused on maize‐bean intercropping, which is experiencing a revival in conventional agricultural settings.
Noa Vazeux‐Blumental+18 more
wiley +1 more source
Variation in histone configurations correlates with gene expression across nine inbred strains of mice. [PDF]
Tyler AL+17 more
europepmc +1 more source
Fall armyworm (FAW) preferred ovipositing on vegetative‐stage soybeans. While ‘mother knows best’ may not apply in soybean‐FAW system, muffled cues in the reproductive stage could positively influence host success. Abstract BACKGROUND While the mother knows best/preference performance hypothesis has been well tested in natural ecosystems, how these ...
Krishnarao Gandham+4 more
wiley +1 more source