Results 111 to 120 of about 2,324,041 (334)

Effects of genetics and sex on adolescent behaviors following neonatal ethanol exposure in BXD recombinant inbred strains. [PDF]

Front Neurosci, 2023
Baker JA, Mulligan MK, Hamre KM.
europepmc   +1 more source

Glucose homeostasis and tissue transcript content of insulin signaling intermediates in four inbred strains of mice: C57BL/6, C57BLKS/6, DBA/2, and 129X1.

Endocrinology, 2004
Transgenic mice phenotypes generally depend on the background strains used in their creation. To examine the effects of genetic background on insulin signaling, we analyzed glucose homeostasis in four inbred strains of mice [C57BL/6 (B6), C57BLKS/6 (KLS),
H. Goren, R. Kulkarni, C. Kahn
semanticscholar   +1 more source

Functional validation of a white pupae minimal gene construct in Ceratitis capitata (Diptera: Tephritidae)

Insect Science, EarlyView.
An intronless version of the white pupae (wp) gene was engineered to restore the wild type brown puparium color in white pupae phenotype mutants of the Mediterranean fruit fly, Ceratitis capitata. Functionality of the minimal gene version (mini‐wp) was verified in vivo, as one copy of mini‐wp successfully restored the wild type phenotype in homozygous ...
Lucas Henrique Figueiredo Prates, Roswitha A. Aumann, Inga Sievers, Tanja Rehling, Marc F. Schetelig   +4 more
wiley   +1 more source

DNA Methylation Changes More Slowly Than Physiological States in Response to Weight Loss in Genetically Diverse Mouse Strains

Frontiers in Endocrinology, 2019
Responses to a high fat, high sucrose (HFHS) diet vary greatly among inbred strains of mice. We sought to examine the epigenetic (DNA methylation) changes underlying these differences as well as variation in weight loss when switched to a low-fat chow ...
Chantle R. Edillor, Brian W. Parks, Margarete Mehrabian, Aldons J. Lusis, Aldons J. Lusis, Matteo Pellegrini   +5 more
doaj   +1 more source

Which mouse multiparental population is right for your study? The Collaborative Cross inbred strains, their F1 hybrids, or the Diversity Outbred population. [PDF]

G3 (Bethesda), 2023
Keele GR.
europepmc   +1 more source

Aging‐Associated Vacuolation of Multi‐Ciliated Cells in the Distal Mouse Oviduct Reflects Unique Cell Identity and Luminal Microenvironment

Aging Cell, EarlyView.
Multi‐ciliated cells in the infundibulum and ampulla (INF/AMP) epithelium are vacuolated in aging. Unique cellular susceptibility of the INF/AMP epithelial population and aging‐associated decline in ovarian artery circulation, which supports the ovary and INF/AMP, contribute to this region‐specific vacuolation phenotype, as a consequence of a mildly ...
Keerthana Harwalkar, Nobuko Yamanaka, Alain S. Pacis, Selina Zhao, Katie Teng, Warwick Pitman, Mitaali Taskar, Vera Lynn, Alex Frances Thornton, Matthew J. Ford, Yojiro Yamanaka   +10 more
wiley   +1 more source

Does tolerance to ethanol-induced ataxia explain the sensitized response to ethanol?

Frontiers in Psychiatry
Under conditions of repeated exposure to ethanol, a sensitized locomotor stimulant response develops in some strains of mice. It has been hypothesized that the sensitized response is a consequence of tolerance development to the sedative/incoordinating ...
Cheryl Reed, Cheryl Reed, Tamara J. Phillips, Tamara J. Phillips, Tamara J. Phillips   +4 more
doaj   +1 more source

Comparison of Ovarian Morphology and Follicular Disturbances between Two Inbred Strains of Cotton Rats (Sigmodon hispidus). [PDF]

Animals (Basel), 2021
Islam MR, Ichii O, Nakamura T, Irie T, Shinohara A, Masum MA, Otani Y, Namba T, Chuluunbaatar T, Elewa YHA, Kon Y.   +10 more
europepmc   +1 more source

Phenotypic characteristics of commonly used inbred mouse strains

Journal of molecular medicine, 2020
W. Y. Tam, K. Cheung
semanticscholar   +1 more source

Targeting IGF1‐Induced Cellular Senescence to Rejuvenate Hair Follicle Aging

Aging Cell, EarlyView.
Age‐related increases in IGF‐1 expression in the skin accelerate stem cell exhaustion and senescence by impairing SIRT1 function, ultimately driving hair follicle aging. Conversely, activating SIRT1, clearing senescent cells, or adopting dietary restriction can mitigate excessive IGF‐1 signaling and provide a promising strategy to rejuvenate hair ...
Yang Wang, Jian Yang, Yue Luo, Zhiqiang Zhao, Yawen Yuan, Juan Li, Yang Liu, Yong Yi, Xiaoke Xu, Yuankunyu Lan, Juan Zou, Qintong Li, Liang Wang, Yang Pan, Yuanhan Yang, Muzhao Xiong, Min Wu, Jinsong Li, Weiyuxin Li, Yujun Zhang, Yang Cao, Yi Zhu, Zhi‐Xiong Jim Xiao   +22 more
wiley   +1 more source