Results 161 to 170 of about 169,377 (260)

Technical considerations and review of urinary microRNAs as biomarkers for chronic kidney disease in dogs and cats

open access: yesVeterinary Clinical Pathology, EarlyView.
Abstract MicroRNAs (miRNAs or miRs) are small, non‐coding RNAs that play a crucial role in gene regulation, making them potential biomarkers for various diseases. In the field of veterinary medicine, there is a growing interest in exploring the diagnostic and therapeutic potential of miRNAs in kidney diseases affecting dogs and cats.
Candice P. Chu, Mary B. Nabity
wiley   +1 more source

Effects of tempol on renal medullary tissue hypoxia in an ovine model of Gram‐negative septic acute kidney injury

open access: yesExperimental Physiology, EarlyView.
Abstract Renal arterial infusion of tempol (RAT) at the onset of Gram‐negative sepsis can prevent sepsis‐induced medullary tissue hypoxia and acute kidney injury (AKI). However, it is not known whether treatment with tempol at a clinically relevant time point of sepsis is similarly effective. Thus, we examined whether tempol can reverse renal medullary
Rachel Peiris   +10 more
wiley   +1 more source

Adenine nucleotide translocator and ATP synthase cooperate in mediating the mitochondrial permeability transition

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Both ATP synthase and adenine nucleotide translocator (ANT) play key roles in mediating the permeability transition. The contribution of ANT becomes evident in the presence of atractylate (ATR) at pH 6.5, a condition that prevents ATP synthase channel activity. At pH 7.4, this effect is minimal, suggesting a critical role for ATP
Ludovica Tommasin   +7 more
wiley   +1 more source

Neurotropic Properties of AAV-PHP.B Are Shared among Diverse Inbred Strains of Mice. [PDF]

open access: yesMol Ther, 2019
Matsuzaki Y   +6 more
europepmc   +1 more source

Mitochondrial haplotype and sex modulate responses to endurance exercise training

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Using OKC‐HETB/W rats we demonstrate that mitochondrial haplotype influences training responses of endurance exercise. Overall OKC‐HETW rats showed greater responses than OKC‐HETB in exercise tolerance, mitochondrial bioenergetics, mitochondrial DNA (mtDNA) mutation frequencies and motor co‐ordination.
Bumsoo Ahn   +8 more
wiley   +1 more source

Genetic Contribution to Initial and Progressive Alcohol Intake Among Recombinant Inbred Strains of Mice. [PDF]

open access: yesFront Genet, 2018
Mulligan MK   +9 more
europepmc   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

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