Results 11 to 20 of about 119,767 (218)
Analysis of structural variation among inbred mouse strains
BMC Genomics, 2023 Background ‘Long read’ sequencing methods have been used to identify previously uncharacterized structural variants that cause human genetic diseases.
Ahmed Arslan +10 more
doaj +1 more source
Inbred mouse strains and genetic stability: a review
Animal, 2011 Inbred mice were essential animal models for scientific research during the 20th century and will contribute decisive results in the current and next centuries.
J. Casellas
doaj +1 more source
Rift Valley Fever Virus Is Lethal in Different Inbred Mouse Strains Independent of Sex
Frontiers in Microbiology, 2020 Rift Valley fever virus (RVFV) is a zoonotic arbovirus affecting humans and livestock in Africa and the Arabian Peninsula. The majority of human cases are mild and self-limiting; however, severe cases can result in hepatitis, encephalitis, or hemorrhagic
Haley N. Cartwright +5 more
doaj +1 more source
Frontiers in Genetics, 2014 Genetic factors influence Fetal Alcohol Spectrum Disorders (FASD) in both humans and animals. Experiments using inbred and selectively bred mouse stocks that controlled for 1) ethanol dose, 2) maternal and fetal blood ethanol levels, and 3) fetal ...
David eGilliam
doaj +1 more source
Sperm morphology in two house mouse subspecies: do wild-derived strains and wild mice tell the same story? [PDF]
PLoS ONE, 2014 Being subject to intense post-copulatory selection, sperm size is a principal determining component of male fitness. Although previous studies have presented comparative sperm size data at higher taxonomic levels, information on the evolution of sperm ...
Jana Albrechtová +4 more
doaj +1 more source
A low coefficient of variation in hepatic triglyceride concentration in an inbred rat strain
Lipids in Health and Disease, 2020 Background Inbred strains are characterized by less genetic variation, which suggests usefulness of inbred strains for evaluations of various parameters.
Tomoko Shimoda +8 more
doaj +1 more source
Shiyan dongwu yu bijiao yixue, 2023 Objective To establish a set of single nucleotide polymorphisms (SNP) detection protocol for inbred rats based on multiplex PCR-ligase detection reaction (LDR).Methods A total of 40 rats SNP sites were selected on chromosomes 1-20 and X of rats among 5 ...
ZHAO Liya +7 more
doaj +1 more source
Differences in Exercise Capacity and Responses to Training in 24 Inbred Mouse Strains
Frontiers in Physiology, 2017 Changes in cardiorespiratory fitness in response to a standardized exercise training protocol differ substantially between individuals. Results from cross-sectional, twin, and family studies indicate genetics contribute to individual differences in both ...
Joshua J. Avila +2 more
doaj +1 more source
Strain-Dependent Modifier Genes Determine Survival in Zfp423 Mice
G3: Genes, Genomes, Genetics, 2020 Zfp423 encodes a transcriptional regulatory protein that interacts with canonical signaling and lineage pathways. Mutations in mouse Zfp423 or its human ortholog ZNF423 are associated with a range of developmental abnormalities reminiscent of ...
Wendy A. Alcaraz +11 more
doaj +1 more source
BMC Genomics, 2005 Background The laboratory rat (Rattus norvegicus) is an important model for studying many aspects of human health and disease. Detailed knowledge on genetic variation between strains is important from a biomedical, particularly pharmacogenetic point of ...
Hedrich Hans J +5 more
doaj +1 more source