Whole Genome Sequence of Two Wild-Derived Mus musculus domesticus Inbred Strains, LEWES/EiJ and ZALENDE/EiJ, with Different Diploid Numbers [PDF]
G3: Genes, Genomes, Genetics, 2016 Wild-derived mouse inbred strains are becoming increasingly popular for complex traits analysis, evolutionary studies, and systems genetics. Here, we report the whole-genome sequencing of two wild-derived mouse inbred strains, LEWES/EiJ and ZALENDE/EiJ ...
Andrew P. Morgan +6 more
doaj +2 more sources
Interfrontal Bone Among Inbred Strains of Mice and QTL Mapping [PDF]
Frontiers in Genetics, 2019 The interfrontal bone (IF) is a minor skeletal trait residing between the frontal bones. IF is considered a quasi-continuous trait. Genetic and environmental factors appear to play roles in its development. The mechanism(s) underlying IF bone development
Heather Zimmerman +4 more
doaj +2 more sources
B Cell Defects Observed in Nod2 Knockout Mice Are a Consequence of a Dock2 Mutation Frequently Found in Inbred Strains [PDF]
J Immunol, 2018 Serre-Yu Wong +8 more
openalex +2 more sources
A phenotypic and molecular characterization of the fmr1-tm1Cgr Fragile X mouse [PDF]
, 2004 Fragile X Syndrome is the most common form of\ud inherited mental retardation. It is also known for having\ud a substantial behavioral morbidity, including autistic features. In humans, Fragile X Syndrome is almost always\ud caused by inactivation of the
Bauchwitz, Dr. Robert P.
core +1 more source
Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli [PDF]
, 2015 Aberrations in the elaboration of both aversive and rewarding stimuli characterize several psychopathologies including anxiety, depression and addiction.
ANDOLINA, DIEGO +2 more
core +1 more source
Frontiers in Genetics, 2014 Genetic factors influence Fetal Alcohol Spectrum Disorders (FASD) in both humans and animals. Experiments using inbred and selectively bred mouse stocks that controlled for 1) ethanol dose, 2) maternal and fetal blood ethanol levels, and 3) fetal ...
David eGilliam
doaj +1 more source
High-Density Genotypes of Inbred Mouse Strains: Improved Power and Precision of Association Mapping. [PDF]
, 2015 Human genome-wide association studies have identified thousands of loci associated with disease phenotypes. Genome-wide association studies also have become feasible using rodent models and these have some important advantages over human studies ...
Churchill, Gary A +6 more
core +1 more source
Sperm morphology in two house mouse subspecies: do wild-derived strains and wild mice tell the same story? [PDF]
PLoS ONE, 2014 Being subject to intense post-copulatory selection, sperm size is a principal determining component of male fitness. Although previous studies have presented comparative sperm size data at higher taxonomic levels, information on the evolution of sperm ...
Jana Albrechtová +4 more
doaj +1 more source
Of faeces and sweat. How much a mouse is willing to run: having a hard time measuring spontaneous physical activity in different mouse sub-strains [PDF]
, 2017 Physical activity has multiple beneficial effects in the physiology and pathology of the organism. In particular, we and other groups have shown that running counteracts cancer cachexia in both humans and rodents.
Adamo, Sergio +2 more
core +3 more sources
A low coefficient of variation in hepatic triglyceride concentration in an inbred rat strain
Lipids in Health and Disease, 2020 Background Inbred strains are characterized by less genetic variation, which suggests usefulness of inbred strains for evaluations of various parameters.
Tomoko Shimoda +8 more
doaj +1 more source