Results 41 to 50 of about 152,020 (319)

Genomic signatures of extensive inbreeding in Isle Royale wolves, a population on the threshold of extinction

open access: yesScience Advances, 2018
Extended runs of homozygosity harboring recessive mutations underlie severe inbreeding depression in Isle Royale wolves. The observation that small isolated populations often suffer reduced fitness from inbreeding depression has guided conservation ...
Jacqueline A. Robinson   +6 more
semanticscholar   +1 more source

Inbreeding management and optimization of genetic gain with phenotypic and genomic selection in oil palm (Elaeis guineensis)[W776] [PDF]

open access: yes, 2020
Oil palm breeding relies on reciprocal recurrent selection between two heterotic groups complementary for bunch number and average bunch weight. Given the long generation interval and the limited selection intensity imposed by the progeny tests currently
Cros, David   +2 more
core  

Relationships between estimated autozygosity and complex traits in the UK Biobank [PDF]

open access: yes, 2018
Inbreeding increases the risk of certain Mendelian disorders in humans but may also reduce fitness through its effects on complex traits and diseases. Such inbreeding depression is thought to occur due to increased homozygosity at causal variants that ...
Evans, Luke M   +2 more
core   +5 more sources

Consistent scaling of inbreeding depression in space and time in a house sparrow metapopulation

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2020
Significance Inbreeding often causes negative effects that, according to theory, may vary in severity with population size or harshness of the environment.
A. Niskanen   +15 more
semanticscholar   +1 more source

Comprehensive analysis of inbreeding depression across growth, fertility, and survival traits in Limousine beef cattle

open access: yesAnimal
The Italian Limousine cattle population, with approximately 100 000 registered animals in the national herd book, plays a crucial role in the country’s national beef industry, being one of the most widely spread breeds in Italy.
S. Callegaro   +5 more
doaj   +1 more source

Measuring the effect of environmental stress on inbreeding depression alone obscures the relative importance of inbreeding–stress interactions on overall fitness in Callosobruchus maculatus

open access: yesEvolutionary Applications, 2020
Environmental stress can have a profound effect on inbreeding depression. Quantifying this effect is of particular importance in threatened populations, which are often simultaneously subject to both inbreeding and environmental stress.
Amy L. Springer   +2 more
doaj   +1 more source

Purging of Strongly Deleterious Mutations Explains Long-Term Persistence and Absence of Inbreeding Depression in Island Foxes.

open access: yesCurrent Biology, 2018
The recovery and persistence of rare and endangered species are often threatened by genetic factors, such as the accumulation of deleterious mutations, loss of adaptive potential, and inbreeding depression [1].
Jacqueline A. Robinson   +4 more
semanticscholar   +1 more source

Genetic Diversity, Adaptation, Wild Introgression, and Coat Color Mutation of Golden Yak

open access: yesAnimal Research and One Health, EarlyView.
Genetic diversity, adaptation, wild introgression, and coat color mutation of golden yak from two populations on the Qinghai‐Xizang Plateau. ABSTRACT The golden yak lives on the Qinghai‐Xizang Plateau with a golden coat and adapts to high altitudes and strong ultraviolet environment. The golden coat is a prominent phenotype in many domesticated species,
Huixuan Yan   +15 more
wiley   +1 more source

Genomic selection requires genomic control of inbreeding

open access: yesGenetics Selection Evolution, 2012
Background In the past, pedigree relationships were used to control and monitor inbreeding because genomic relationships among selection candidates were not available until recently.
Sonesson Anna K   +2 more
doaj   +1 more source

When does female multiple mating evolve to adjust inbreeding? : Effects of inbreeding depression, direct costs, mating constraints, and polyandry as a threshold trait [PDF]

open access: yes, 2016
Ackowledgements: This work was funded by a European Research Council Starting Grant to JMR. All simulations were performed using the Maxwell computing cluster at the University of AberdeenPeer reviewedPublisher ...
Bocedi, Greta   +2 more
core   +2 more sources

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