Results 201 to 210 of about 1,793,238 (381)
Molecular Oncology, EarlyView.C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald +18 more
wiley +1 more source
The Effective Design of Managerial Incentive Systems:Combining Theoretical Principles and Practical Trade'-offs. [PDF]
On the use of theoretical developments in agency economics for the practical design of incentive- and performance-based compensation systems.managerial compensation; principal-agent theory; incentive and performance based compensation ...
Alessandro Rossi
core
Eight drive-reward combinations: A test of incentive-motivational theory [PDF]
, 1976 W. Miles Cox
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Cultural Incentive Learning: How Culture Shapes Acquisition of Values. [PDF]
Evol AnthropolRigoli F, Lennon J.
europepmc +1 more source
Commitment and optimal incentive [PDF]
We propose an extended principal-agent model considering employee commitment and describe how to motivate committed agent, who not only shows regard for his own income but also cares the organizational benefit.
Liu, Taoxiong, Zhou, Bihua
core +1 more source
Jephcott Lecture. Full Employment and Incentives in a Healthy Society
, 1966 Paul Chambers
openalex +1 more source
Molecular Oncology, EarlyView.TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach +8 more
wiley +1 more source
Incentive Effects of Social Security Under an Uncertain Disability Option [PDF]
Incentive effects of pension systems are usually estimated under the assumption that the institutional environment provides a single optimal 'pathway' for retirement.
Axel Boersch-Supan
core
EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines
Molecular Oncology, EarlyView.The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche +8 more
wiley +1 more source