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Plasmid double locus sequence typing for IncHI2 plasmids, a subtyping scheme for the characterization of IncHI2 plasmids carrying extended-spectrum β-lactamase and quinolone resistance genes [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2010
IncHI2 plasmids are frequently encountered in clinical enterobacterial strains associated with the dissemination of relevant antimicrobial resistance genes. These plasmids are usually >250 kb, and technical difficulties can impair plasmid DNA purification and comparison by restriction fragment length polymorphism. We analysed the available IncHI2 whole
Aurora García-Fernández   +1 more
exaly   +4 more sources

Evolution of IncHI2 plasmids via acquisition of transposons carrying antibiotic resistance determinants [PDF]

open access: yesJournal of Antimicrobial Chemotherapy, 2012
To investigate the relationships between IncHI2 plasmids conferring resistance to antibiotics isolated in Australia and those from other countries.PCR, restriction digestion, cloning and DNA sequencing were used to characterize transposons and determine their location in IncHI2 plasmids recovered from Salmonella enterica isolates from Australian ...
Amy K Cain, Ruth M Hall
exaly   +3 more sources
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RamAp Is an Efflux Pump Regulator Carried by an IncHI2 Plasmid

Antimicrobial Agents and Chemotherapy, 2022
In investigating the epidemiological trends of Salmonella enterica serovar Goldcoast, we previously identified several closely related strains with different MICs to azithromycin and quinolones. Genome sequencing and comparison of two very similar multidrug-resistant (MDR) strains, R18.0877 and R18.1656, has led to ...
Yu-Ping Hong   +5 more
openaire   +2 more sources

Arsenical resistance in the IncHI2 plasmids

Plasmid, 2002
The IncHI2 plasmid R478, like other arsenic resistance IncH plasmids, provides increased levels of resistance to sodium arsenate (up to 100mM) and sodium arsenite (up to 10mM) to the host cell. An arsenic resistance fragment of R478 was cloned and sequenced revealing four arsenic resistance associated gene homologues, arsR, arsB, arsC, and arsH.
David, Ryan, Emer, Colleran
openaire   +2 more sources

Conjugative IncHI2 plasmid harboring novel class 1 integron mediated dissemination of multidrug resistance genes in Salmonella Typhimurium

Food Control, 2021
Abstract Salmonella enterica serovar Typhimurium is one of the most important serovars among nontyphoidal Salmonella. The inappropriate and over usage of antimicrobials in clinical and animal husbandry has increased the prevalence of antimicrobial-resistant Salmonella Typhimurium (S. Typhimurium).
Arunachalam Kannappan   +2 more
exaly   +2 more sources

pIN32: a Cointegrate Plasmid with IncHI2 and IncFII Components

Microbiology, 1986
An Enterobacter cloacae strain isolated from the faeces of a child with diarrhoea in Indonesia contained a transferable 216 MDa plasmid, pIN32, exhibiting IncHI2 phenotypic characters, including temperature sensitivity of transfer and the expression of H serotype pili at a repressed level.
D E, Bradley   +5 more
openaire   +2 more sources

Co-spread of metal and antibiotic resistance within ST3-IncHI2 plasmids from E. coli isolates of food-producing animals

open access: yesScientific Reports, 2016
AbstractConcerns have been raised in recent years regarding co-selection for antibiotic resistance among bacteria exposed to heavy metals, particularly copper and zinc, used as growth promoters for some livestock species. In this study, 25 IncHI2 plasmids harboring oqxAB (20/25)/blaCTX-M (18/25) were found with sizes ranging from ∼260 to ∼350 kb and 22
Liang Li, Jian Sun
exaly   +3 more sources

Characteristics of Two mcr-1-Harboring IncHI2 Plasmids from Clinical Salmonella Isolates in Jiaxing City

Foodborne Pathogens and Disease, 2023
Salmonella is a primary cause of foodborne diseases, and the increasing prevalence of mcr-1-carrying plasmids, which confer colistin resistance to Salmonella, poses significant global health concerns. As the frequency of occurrence of the mcr-1 gene is increasing globally, we studied the prevalence of mcr-1 in clinical Salmonella isolates by analyzing ...
Miaomiao Jia   +8 more
openaire   +2 more sources

Characterization of the IncHI2 plasmid pTW4 harboring tet(M) from an isolate of Escherichia coli ST162

The Journal of Antibiotics, 2020
To investigate the genetic features and biological costs of the plasmid pTW4 harboring tet(M) in an isolate of Escherichia coli ST162 from a duck. The complete nucleotide sequence of plasmid pTW4 was determined. The characteristics of plasmid pTW4 in E. coli were investigated by stability and direct competition assays.
Ying-Ying, Liu   +9 more
openaire   +2 more sources

Genomic characterization of an extensively drug-resistant chicken-borne Salmonella Indiana isolate carrying an IncHI2-IncHI2A plasmid

Food Control, 2021
Abstract The recent emergence of e xtensively d rug- r esistant (XDR) foodborne bacteria is posing a huge threat to food safety and public health. In this study, we reported the genome features of an XDR Salmonella Indiana isolate (SJTUF 87912v2 ) recovered from a chicken carcass in 2012 in Guangdong, China.
Zengfeng Zhang   +5 more
openaire   +1 more source

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