Results 71 to 80 of about 2,197,479 (275)

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

The airway microbiome of persons with cystic fibrosis correlates with acquisition and microbiological outcomes of incident Stenotrophomonas maltophilia infection

Frontiers in Microbiology
RationaleChronic infection with Stenotrophomonas maltophilia in persons with cystic fibrosis (pwCF) has been linked to an increased risk of pulmonary exacerbations and lung function decline.
Lauren A. Bowron, Nicole Acosta, Christina S. Thornton, Christina S. Thornton, Jennifer Carpentero, Barbara-Jean M. Waddell, Lalit Bharadwaj, Kirsten Ebbert, Kirsten Ebbert, Daniel Castañeda-Mogollón, John M. Conly, John M. Conly, Harvey R. Rabin, Harvey R. Rabin, Michael G. Surette, Michael D. Parkins, Michael D. Parkins   +16 more
doaj   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Interference of surface plasmon polaritions controlled by the phase of incident light

, 2008
Interference patterns of surface plasmon polaritons(SPPs) are observed in the extraordinary optical transmission through subwavelength holes in optically thick metal plate. It is found that the phase of incident light can be transferred to SPPs.
Bouhelier A., Guang-Can Guo, Guo-Ping Guo, Pei Zhang, Xi-Feng Ren, Yun-Feng Huang, Zhi-Wei Wang   +6 more
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

METHODOLOGY OF PROBABILISTIC EVALUATING OF CURRENT ACCIDENT RATE BASED ON THE FACTORIAL ANALYSIS OF AVIATION EVENTS

Научный вестник МГТУ ГА, 2016
Methodological approach to cumulative quantitative estimation of safety level is presented through probabilistic (frequency) indices of aviation events on the record, taking into account the importance of their сause factors.
A. M. Lushkin
doaj  

Radioprotection incidents et accidents survenus lors de la réalisation de l’hystérosalpingographie au centre hospitalier Akram de Limete/Kinshasa-R.D. Congo

Revue des Sciences de la Santé
Le sujet qui fait l’objet de notre investigation s’intitule : « Incidents et accidents causé lors de la réalisation de l’hystérosalpingographie(HSG) », dont en voici la définition de quelques mots-clés : - Incident : qui survient accessoirement dans une ...
Michel KAJABIKA CIDUNDA, Samson KOBISI MBEKA, Jean-Baptiste MANIONGA Z’ONZA ZING, Arthur MUNANGA LUPONGO, Firmin KUSINZA MUBALAMA   +4 more
doaj   +1 more source

TRANSFORMATION OF THE INSTITUTE OF IRRESISTIBLE FORCE: HISTORICAL AND LEGAL ANALYSIS [PDF]

Legal Bulletin
In recent years, there has been an obvious popularization of the institution of force majeure as a way of exemption from civil liability caused by the inability to fulfill obligations assumed under the contract. Such actualization is primarily associated
IVANENKO TIMOFEY
doaj   +1 more source

A partial wave analysis of the $\pi ^0\pi ^0$ system produced in $\pi ^-p$ charge exchange collisions

, 2000
A partial wave analysis of the of the $\pi ^0\pi ^0$ system produced in the charge exchange reaction: $\pi ^-p\to \pi ^0\pi ^0n$ at an incident momentum of $18.3 GeV/c$ is presented as a function of ${\pi ^0\pi ^0}$ invariant mass, $m_{\pi^0\pi^0}$, and ...
A. A. Yershov, A. H. Sanjari, A. I. Ostrovidov, A. P. Szczepaniak, A. R. Dzierba, A. V. Popov, A.C. Irving, A.C. Irving, A.V. Anisovich, A.V. Anisovich, C. Olchanski, D. Alde, D. Alde, D. B. White, D. Barberis, D. I. Ryabchikov, D. L. Steinike, D. P. Weygand, D. R. Rust, D. R. Thompson, D. S. Brown, D. Zhao, E. I. Ivanov, E. King, E. Scott, G. Grayer, G. S. Adams, H. J. Willutzki, I. A. Kachaev, I. N. Vardanyan, J. A. Smith, J. Gunter, J. J. Manak, J. Kuhn, J. M. Bishop, J. M. LoSecco, J. Napolitano, J. P. Cummings, J. P. Dowd, J. Wise, K. A. Plinske, K. Danyo, K. K. Seth, K.L. Au, L. I. Sarycheva, M. A. Kostin, M. Harada, M. Hayek, M. Nozar, M. R. Shepherd, M. Witkowski, N. B. Sinev, N. M. Cason, N. Shenhav, N.N. Achasov, O. L. Kodolova, P. Estabrooks, P. Estabrooks, P. Eugenio, P. Minkowski, P. T. Smith, R. Kaminski, R. Lindenbusch, R. W. Hackenburg, R.R. Crittenden, S. A. Taegar, S. Fukui, S. Godfrey, S. P. Denisov, S. Teige, S. Teige, S. U. Chung, S.U. Chung, T. Adams, T. Adams, T. K. Pedlar, T. Sulanke, V. A. Bodyagin, V. A. Dorofeev, V. L. Korotkikh, V. V. Lipaev, V.V. Anisovich, V.V. Anisovich, W. D. Shephard, W. Hoogland, W. Kern, W.D. Apel, Z. Bar-Yam, Z. Bar-Yam   +88 more
core   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source