Results 1 to 10 of about 236,953 (124)
Abstract The skin functions as the primary barrier organ in humans, safeguarding against environmental insults and challenges. Continuous skin turnover and effective immunosurveillance are critical for maintaining skin homeostasis and preventing the development of skin cancers induced by physical (ultraviolet [UV] irradiation), chemical ...
Han-Chi Tseng, Po-Ta Lai, Chih-Hung Lee
openaire +3 more sources
Exposure assessment and carcinogenic risk characterization of industrial chemical emissions in incheon, South Korea. [PDF]
Rapid industrialization has intensified chemical emissions, raising urgent concerns about carcinogenic risks to surrounding communities. This study assessed the spatial distribution of industrial facilities emitting chemicals in Incheon Metropolitan City,
Choi Y, Kim H, Jeong TY, Kim SD.
europepmc +2 more sources
Carcinogenesis Associated with Toxin Nephropathy: Proposed Mediation by Phosphate Toxicity. [PDF]
Although cancer is often considered a genetic disease, genotoxic damage to nuclear DNA caused by carcinogens is not always sufficient to stimulate cancer cell growth, suggesting that other etiological factors are involved.
Brown RB, Mielke JG.
europepmc +2 more sources
Development of Korean CARcinogen EXposure: IARC Group 2A Carcinogens [PDF]
Backgrounds: Reliable exposure data are critical for occupational cancer prevention and epidemiological studies. We developed the Korean CARcinogen EXposure (K-CAREX) to provide exposure prevalence and intensity for 20 carcinogens classified as Group 1 ...
Koh D+9 more
europepmc +2 more sources
Cancer of the uterine cervix occurs with high frequency in black females of several populations of Southern Africa. It accounts for 40-50% of all cancers in Black females in the Johannesburg area and for over 40% of those in women in the rural lowveld area of the Transvaal. The aetiology of this cancer has several distinct features, almost all of which
J. S. Harington
openaire +2 more sources
Food-Borne Chemical Carcinogens and the Evidence for Human Cancer Risk
Commonly consumed foods and beverages can contain chemicals with reported carcinogenic activity in rodent models. Moreover, exposures to some of these substances have been associated with increased cancer risks in humans.
Tetyana Kobets+2 more
doaj +1 more source
Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage [PDF]
Abstract Cancer prevention is a cost-effective alternative to treatment. In mice, the mTOR inhibitor rapamycin prevents distinct spontaneous, noninflammatory cancers, making it a candidate broad-spectrum cancer prevention agent. We now show that oral microencapsulated rapamycin (eRapa) prevents skin cancer in dimethylbenz(a)anthracene ...
Srilakshmi Pandeswara+10 more
openaire +3 more sources
Investigating the different mechanisms of genotoxic and non-genotoxic carcinogens by a gene set analysis. [PDF]
Based on the process of carcinogenesis, carcinogens are classified as either genotoxic or non-genotoxic. In contrast to non-genotoxic carcinogens, many genotoxic carcinogens have been reported to cause tumor in carcinogenic bioassays in animals.
Won Jun Lee+7 more
doaj +1 more source
Ethno-medicines have been playing a vital role throughout human history in the day to day healthcare routine. Before the evolution of western medicine, for thousands of years, people have been using traditional medicine for the treatment of different diseases.
C. Joy Hepzibah, V. David Arputha Raj
openaire +1 more source
Tobacco smoking as risk factor of laryngeal cancer
Introduction: Laryngeal cancer is one of the most common type of head and neck cancers. It develops due to spontaneous mutation or influence of external factors (physical, biological and chemical).
Michał Konopelko+4 more
doaj +3 more sources