Results 1 to 10 of about 226,316 (224)

The differential role of aryl hydrocarbon receptor in skin cancers induced by environmental carcinogens, including ultraviolet irradiation, arsenic exposure, and HPV infection

Dermatologica Sinica
Abstract The skin functions as the primary barrier organ in humans, safeguarding against environmental insults and challenges. Continuous skin turnover and effective immunosurveillance are critical for maintaining skin homeostasis and preventing the development of skin cancers induced by physical (ultraviolet [UV] irradiation), chemical ...
Han-Chi Tseng, Po-Ta Lai, Chih-Hung Lee
openaire   +3 more sources

DNA Methylation as a Molecular Mechanism of Carcinogenesis in World Trade Center Dust Exposure: Insights from a Structured Literature Review. [PDF]

Biomolecules
The collapse of the World Trade Center (WTC) buildings in New York City generated a large plume of dust and smoke. WTC dust contained human carcinogens including metals, asbestos, polycyclic aromatic hydrocarbons (PAHs), persistent organic pollutants ...
Tuminello S, Durmus N, Snuderl M, Chen Y, Shao Y, Reibman J, Arslan AA, Taioli E.   +7 more
europepmc   +2 more sources

Epidemiology and aetiology of cancer of the uterine cervix including the detection of carcinogenic N-nitrosamines in the human vaginal vault.

South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1975
Cancer of the uterine cervix occurs with high frequency in black females of several populations of Southern Africa. It accounts for 40-50% of all cancers in Black females in the Johannesburg area and for over 40% of those in women in the rural lowveld area of the Transvaal. The aetiology of this cancer has several distinct features, almost all of which
J. S. Harington
openaire   +2 more sources

Key characteristics of carcinogens meet hallmarks for prevention-cutting the Gordian knot. [PDF]

Front Oncol
The complexity of cancer requires a comprehensive approach to understand its diverse manifestations and underlying mechanisms. Initially outlined by Hanahan and Weinberg in 2000 and updated in 2010, the hallmarks of cancer provide a conceptual basis for ...
Senga SS, Bisson WH, Colacci A.
europepmc   +2 more sources

Food-Borne Chemical Carcinogens and the Evidence for Human Cancer Risk

Foods, 2022
Commonly consumed foods and beverages can contain chemicals with reported carcinogenic activity in rodent models. Moreover, exposures to some of these substances have been associated with increased cancer risks in humans.
Tetyana Kobets, Benjamin P. C. Smith, Gary M. Williams   +2 more
doaj   +1 more source

Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage [PDF]

Cancer Prevention Research, 2015
Abstract Cancer prevention is a cost-effective alternative to treatment. In mice, the mTOR inhibitor rapamycin prevents distinct spontaneous, noninflammatory cancers, making it a candidate broad-spectrum cancer prevention agent. We now show that oral microencapsulated rapamycin (eRapa) prevents skin cancer in dimethylbenz(a)anthracene ...
Srilakshmi Pandeswara, Danielle A. Callaway, Yang Liu, Yang Liu, Zelton D Sharp, Paul Hasty, Sherry G. Dodds, Aijie Liu, Vinh Dao, Vincent Hurez, Tyler J. Curiel   +10 more
openaire   +3 more sources

Ocimum sanctum linn: An ethnomedicinal herb as a potential source of anti-carcinogen against various cancer diseases and effective ways to include the basil in everyday diet

International journal of health sciences, 2022
Ethno-medicines have been playing a vital role throughout human history in the day to day healthcare routine. Before the evolution of western medicine, for thousands of years, people have been using traditional medicine for the treatment of different diseases.
C. Joy Hepzibah, V. David Arputha Raj
openaire   +1 more source

Investigating the different mechanisms of genotoxic and non-genotoxic carcinogens by a gene set analysis. [PDF]

PLoS ONE, 2014
Based on the process of carcinogenesis, carcinogens are classified as either genotoxic or non-genotoxic. In contrast to non-genotoxic carcinogens, many genotoxic carcinogens have been reported to cause tumor in carcinogenic bioassays in animals.
Won Jun Lee, Sang Cheol Kim, Seul Ji Lee, Jeongmi Lee, Jeong Hill Park, Kyung-Sang Yu, Johan Lim, Sung Won Kwon   +7 more
doaj   +1 more source

The research progress in the interaction between Candida albicans and cancers

Frontiers in Microbiology, 2022
Candida albicans is an opportunistic pathogenic fungus, which tends to infect the host with defective immune function including cancer patients. A growing number of studies have shown that C. albicans infection increases the host susceptibility to cancer
Dalang Yu, Zhiping Liu
doaj   +1 more source

Data from Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage

, 2023
<div>Abstract<p>Cancer prevention is a cost-effective alternative to treatment. In mice, the mTOR inhibitor rapamycin prevents distinct spontaneous, noninflammatory cancers, making it a candidate broad-spectrum cancer prevention agent.
Tyler J. Curiel, Zelton D. Sharp, Paul Hasty, Aijie Liu, Danielle Callaway, Sherry Dodds, Vincent Hurez, Yang Liu, Srilakshmi Pandeswara, Vinh Dao   +9 more
openaire   +1 more source