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Food-Borne Chemical Carcinogens and the Evidence for Human Cancer Risk
Commonly consumed foods and beverages can contain chemicals with reported carcinogenic activity in rodent models. Moreover, exposures to some of these substances have been associated with increased cancer risks in humans.
Tetyana Kobets+2 more
doaj +2 more sources
Background Endocrine disrupting chemicals and carcinogens, some of which may not yet have been classified as such, are present in many occupational environments and could increase breast cancer risk. Prior research has identified associations with breast
Brophy James T+11 more
doaj +2 more sources
Abstract The skin functions as the primary barrier organ in humans, safeguarding against environmental insults and challenges. Continuous skin turnover and effective immunosurveillance are critical for maintaining skin homeostasis and preventing the development of skin cancers induced by physical (ultraviolet [UV] irradiation), chemical ...
Han-Chi Tseng, Po-Ta Lai, Chih-Hung Lee
openaire +3 more sources
Exposure assessment and carcinogenic risk characterization of industrial chemical emissions in incheon, South Korea. [PDF]
Rapid industrialization has intensified chemical emissions, raising urgent concerns about carcinogenic risks to surrounding communities. This study assessed the spatial distribution of industrial facilities emitting chemicals in Incheon Metropolitan City,
Choi Y, Kim H, Jeong TY, Kim SD.
europepmc +2 more sources
Carcinogenesis Associated with Toxin Nephropathy: Proposed Mediation by Phosphate Toxicity. [PDF]
Although cancer is often considered a genetic disease, genotoxic damage to nuclear DNA caused by carcinogens is not always sufficient to stimulate cancer cell growth, suggesting that other etiological factors are involved.
Brown RB, Mielke JG.
europepmc +2 more sources
Cancer of the uterine cervix occurs with high frequency in black females of several populations of Southern Africa. It accounts for 40-50% of all cancers in Black females in the Johannesburg area and for over 40% of those in women in the rural lowveld area of the Transvaal. The aetiology of this cancer has several distinct features, almost all of which
J. S. Harington
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DNA Methylation as a Molecular Mechanism of Carcinogenesis in World Trade Center Dust Exposure: Insights from a Structured Literature Review. [PDF]
The collapse of the World Trade Center (WTC) buildings in New York City generated a large plume of dust and smoke. WTC dust contained human carcinogens including metals, asbestos, polycyclic aromatic hydrocarbons (PAHs), persistent organic pollutants ...
Tuminello S+7 more
europepmc +2 more sources
Each year there will be an estimated 2.1 million new lung cancer cases and 1.8 million lung cancer deaths worldwide. Tobacco smoke is the No.1 risk factors of lung cancer, accounting for > 85% lung cancer deaths. Air pollution, or haze, comprises ambient
Guangbiao Zhou
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Key Points Question What is the present degree of exposure to occupational carcinogens, and are occupational carcinogens related to cancer burden over time?
Na Li+15 more
semanticscholar +1 more source
Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage [PDF]
Abstract Cancer prevention is a cost-effective alternative to treatment. In mice, the mTOR inhibitor rapamycin prevents distinct spontaneous, noninflammatory cancers, making it a candidate broad-spectrum cancer prevention agent. We now show that oral microencapsulated rapamycin (eRapa) prevents skin cancer in dimethylbenz(a)anthracene ...
Srilakshmi Pandeswara+10 more
openaire +3 more sources