Results 1 to 10 of about 12,164 (46)

Food-Borne Chemical Carcinogens and the Evidence for Human Cancer Risk

Foods, 2022
Commonly consumed foods and beverages can contain chemicals with reported carcinogenic activity in rodent models. Moreover, exposures to some of these substances have been associated with increased cancer risks in humans.
T. Kobets, Benjamin P. C. Smith, G. Williams   +2 more
semanticscholar   +1 more source

Association of 13 Occupational Carcinogens in Patients With Cancer, Individually and Collectively, 1990-2017

JAMA Network Open, 2021
Key Points Question What is the present degree of exposure to occupational carcinogens, and are occupational carcinogens related to cancer burden over time?
Na Li, Zhen Zhai, Yi Zheng, Shuai Lin, Yujiao Deng, Grace Xiang, Jia Yao, Dong Xiang, Shuqian Wang, Pengtao Yang, Si Yang, P. Xu, Ying Wu, Jingjing Hu, Zhijun Dai, Meng Wang   +15 more
semanticscholar   +1 more source

The mutational signature profile of known and suspected human carcinogens in mice

Nature Genetics, 2020
Epidemiological studies have identified many environmental agents that appear to significantly increase cancer risk in human populations. By analyzing tumor genomes from mice chronically exposed to 1 of 20 known or suspected human carcinogens, we reveal ...
L. Riva, A. Pandiri, Y. R. Li, A. Droop, J. Hewinson, M. Quail, V. Iyer, Rebecca Shepherd, R. Herbert, P. Campbell, R. Sills, L. Alexandrov, A. Balmain, D. Adams   +13 more
semanticscholar   +1 more source

Unboxing the molecular modalities of mutagens in cancer

Environmental science and pollution research international, 2021
The etiology of the majority of human cancers is associated with a myriad of environmental causes, including physical, chemical, and biological factors. DNA damage induced by such mutagens is the initial step in the process of carcinogenesis resulting in
S. Kumari, Sudhanshu Sharma, Dia Advani, A. Khosla, Pravir Kumar, R. K. Ambasta   +5 more
semanticscholar   +1 more source

Application of the key characteristics of carcinogens in cancer hazard identification

Carcinogenesis, 2018
Smith et al. (Env. Health Perspect. 124: 713, 2016) identified 10 key characteristics (KCs), one or more of which are commonly exhibited by established human carcinogens.
K. Guyton, I. Rusyn, W. Chiu, D. Corpet, M. van den Berg, M. Ross, D. Christiani, F. Beland, Martyn T. Smith   +8 more
semanticscholar   +1 more source

Opiate and Tobacco Use and Exposure to Carcinogens and Toxicants in the Golestan Cohort Study

Cancer Epidemiology, Biomarkers and Prevention, 2020
Background: There is little information on human exposure to carcinogens and other toxicants related to opiate use, alone or in combination with tobacco. Methods: Among male participants of the Golestan Cohort Study in Northeast Iran, we studied 28 never
A. Etemadi, H. Poustchi, A. Calafat, B. Blount, V. D. De Jesús, Lanqing Wang, A. Pourshams, Ramin Shakeri, Maki Inoue-Choi, M. Shiels, G. Roshandel, G. Murphy, C. Sosnoff, Deepak Bhandari, June Feng, B. Xia, Yuesong Wang, Lei Meng, F. Kamangar, P. Brennan, P. Boffetta, S. Dawsey, C. Abnet, R. Malekzadeh, N. Freedman   +24 more
semanticscholar   +1 more source

Meat intake, cooking methods, dietary carcinogens, and colorectal cancer risk: findings from the Colorectal Cancer Family Registry

Cancer Medicine, 2015
Diets high in red meat and processed meats are established colorectal cancer (CRC) risk factors. However, it is still not well understood what explains this association.
A. Joshi, Andre E Kim, J. P. Lewinger, C. Ulrich, J. Potter, M. Cotterchio, L. Le Marchand, M. Stern   +7 more
semanticscholar   +1 more source

Therapeutic methods of gut microbiota modification in colorectal cancer management – fecal microbiota transplantation, prebiotics, probiotics, and synbiotics

Gut microbes, 2020
The link between gut microbiota and the development of colorectal cancer has been investigated. An imbalance in the gut microbiota promotes the progress of colorectal carcinogenesis via multiple mechanisms, including inflammation, activation of ...
Karolina Kaźmierczak-Siedlecka, A. Daca, Mateusz Fic, Thierry van de Wetering, M. Folwarski, W. Makarewicz   +5 more
semanticscholar   +1 more source

Impact of occupational carcinogens on lung cancer risk in a general population.

International Journal of Epidemiology, 2013
BACKGROUND Exposure to occupational carcinogens is an important preventable cause of lung cancer. Most of the previous studies were in highly exposed industrial cohorts.
S. De Matteis, D. Consonni, J. Lubin, M. Tucker, S. Peters, R. Vermeulen, H. Kromhout, P. Bertazzi, N. Caporaso, A. Pesatori, S. Wacholder, M. Landi   +11 more
semanticscholar   +1 more source

Endocrine disruptors from the environment affecting breast cancer

Oncology Letters, 2020
Evaluation of carcinogenic substances from the environment is a challenge for scientists. Recently, a novel approach based on 10 key characteristics of human carcinogens classified by the International Agency for Research on Cancer (IARC) has emerged ...
G. Calaf, Richard Ponce-Cusi, F. Aguayo, Juan Mu�oz, Tammy C. Bleak   +4 more
semanticscholar   +1 more source