Results 31 to 40 of about 268,946 (224)

Synthetic Receptors for Early Detection and Treatment of Cancer

open access: yesBiosensors, 2023
Over recent decades, synthetic macrocyclic compounds have attracted interest from the scientific community due to their ability to selectively and reversibly form complexes with a huge variety of guest moieties. These molecules have been studied within a
Frank Davis, Séamus P. J. Higson
doaj   +1 more source

Leukemia and Exposure to Potential Benzene Sources in Children From the Mexico City Metropolitan Area, 2010–2021: A Geospatial Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Leukemia is the most common childhood cancer in Mexico, and acute lymphoblastic leukemia (ALL) is the most frequent subtype. Exposure to high concentrations of benzene has been associated with ALL incidence, particularly in urban areas. This study evaluated the relationship between distance to benzene emission sources and the number
Orlando Rivera Zurita   +5 more
wiley   +1 more source

The differential role of aryl hydrocarbon receptor in skin cancers induced by environmental carcinogens, including ultraviolet irradiation, arsenic exposure, and HPV infection

open access: yesDermatologica Sinica
Abstract The skin functions as the primary barrier organ in humans, safeguarding against environmental insults and challenges. Continuous skin turnover and effective immunosurveillance are critical for maintaining skin homeostasis and preventing the development of skin cancers induced by physical (ultraviolet [UV] irradiation), chemical ...
Han-Chi Tseng, Po-Ta Lai, Chih-Hung Lee
openaire   +2 more sources

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Air pollution as a risk factor for lung cancer [PDF]

open access: yesArchive of Oncology, 2005
Over the past decade, an increasing body of scientific evidence has accrued associating outdoor air pollution with certain types of cancer. Ambient air, particularly in densely populated urban environments, contains a variety of known human carcinogens ...
Nikić Dragana, Stanković Aleksandra M.
doaj   +1 more source

Job Exposure Matrix: Occupational Exposure Assessment to Carcinogenic Compounds

open access: yesAsian Pacific Journal of Environment and Cancer, 2023
The Job Exposure Matrix (JEM) is a cross-tabulation of workplace and job title hazards and is an essential exposure assessment tool for epidemiological studies, cancer risk monitoring, cancer risk prevention, and cancer risk quantification in health ...
Zahra Moradpour   +1 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Self‐Sintering Ionogel Binder for Flexible, Recyclable, and Healable Printed Giant Magnetoresistive Sensors

open access: yesAdvanced Functional Materials, EarlyView.
ABSTRACT Electronic waste has emerged as a major environmental challenge, driven by the massive consumption and a limited lifetime of modern electronic devices, stimulating the development of sustainable electronics. Here, an all‐biomaterial gelatin‐choline‐citric acid ([Ch][CA]) ionogel is developed as an active binder to realize self‐sintered ...
Lin Guo   +10 more
wiley   +1 more source

Genomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast Cancer

open access: yesBreast Cancer: Basic and Clinical Research, 2016
Sporadic breast cancer develops through the accumulation of molecular abnormalities in normal breast tissue, resulting from exposure to estrogens and other carcinogens beginning at adolescence and continuing throughout life.
David N. Danforth
doaj   +1 more source

Genomic and Bioinformatics Approaches for Analysis of Genes Associated With Cancer Risks Following Exposure to Tobacco Smoking

open access: yesFrontiers in Public Health, 2018
Cancer is a significant health problem in the Middle East and global population. It is well established that there is a direct link between tobacco smoking and cancer, which will continue to pose a significant threat to human health.
Mohammed A. I. Al-Obaide   +3 more
doaj   +1 more source

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