Results 61 to 70 of about 291,809 (169)

Mechanisms linking colorectal cancer to the consumption of (processed) red meat : a review [PDF]

open access: yes, 2015
Colorectal cancer (CRC) is the third most commonly diagnosed cancer in the world. The vast majority of CRC cases have been linked to environmental causes rather than to heritable genetic changes.
De Smet, Stefaan   +3 more
core   +2 more sources

Key characteristics of carcinogens meet hallmarks for prevention-cutting the Gordian knot

open access: yesFrontiers in Oncology
The complexity of cancer requires a comprehensive approach to understand its diverse manifestations and underlying mechanisms. Initially outlined by Hanahan and Weinberg in 2000 and updated in 2010, the hallmarks of cancer provide a conceptual basis for ...
Sasi S. Senga   +3 more
doaj   +1 more source

Polycyclic aromatic hydrocarbons and esophageal squamous cell carcinoma [PDF]

open access: yes, 2012
Esophageal cancer (EC) is the 8th most common cancer and the 6th most frequent cause of cancer mortality worldwide. Esophageal squamous cell carcinoma (ESCC) is the most common type of EC.
Dawsey, S.M.   +3 more
core  

Chemoprevention of aberrant crypt foci in the colon of rats by dietary onion [PDF]

open access: yes, 2007
Onion intake might reduce the risk of colorectal cancer, according to epidemiology. However, Femia showed in 2003 that diets with a 20% onion intake increase carcinogenesis in rats. We speculated this dose was too high.
Corpet, Denis E.   +2 more
core   +4 more sources

Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility

open access: yesCadernos de Saúde Pública, 2002
Epidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered ...
Hatagima Ana
doaj  

Tobacco, air pollution, environmental carcinogenesis, and thoughts on conquering strategies of lung cancer

open access: yesCancer Biology & Medicine, 2019
Each year there will be an estimated 2.1 million new lung cancer cases and 1.8 million lung cancer deaths worldwide. Tobacco smoke is the No.1 risk factors of lung cancer, accounting for > 85% lung cancer deaths. Air pollution, or haze, comprises ambient
Guangbiao Zhou
doaj   +1 more source

In silico analysis of molecular docking between nicotine and GSTP1 gene in oral squamous cell carcinoma

open access: yesTrakya University Journal of Natural Sciences
Oral squamous cell carcinoma (OSCC) is a predominant cancer strongly associated with risk factors like use of tobacco, viral infections, and genetic predispositions.
Shashanka Thowdanahalli Munipapanna   +1 more
doaj   +1 more source

A theory for the tissue specificity of BRCA1/2 related and other hereditary cancers [PDF]

open access: yes, 2010
Women who inherit a defective BRCA1 or BRCA2 gene have risks for breast and ovarian cancer that are so high and seem so selective that many mutation carriers choose to have prophylactic surgery. There has been much conjecture to explain such apparently
Bernard Friedenson
core   +1 more source

Investigation of NQO1 genetic polymorphism, NQO1 gene expression and PAH-DNA adducts in ESCC. A case-control study from Iran [PDF]

open access: yes, 2009
We evaluated the effect of NQO1 genetic variation on PAH-DNA adducts in esophageal squamous cell carcinoma (ESCC) in northeast Iran. Golestan Province in northeast of Iran has one of the highest esophageal cancer incidences in the world.
Biramijamal, F.   +4 more
core   +3 more sources

Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility

open access: yesCadernos de Saúde Pública
Epidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered ...
Ana Hatagima
doaj   +2 more sources

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