Results 81 to 90 of about 277,495 (246)
Key characteristics of carcinogens meet hallmarks for prevention-cutting the Gordian knot
Frontiers in OncologyThe complexity of cancer requires a comprehensive approach to understand its diverse manifestations and underlying mechanisms. Initially outlined by Hanahan and Weinberg in 2000 and updated in 2010, the hallmarks of cancer provide a conceptual basis for ...
Sasi S. Senga +3 more
doaj +1 more source
Cancer Incidence Among Swedish Seafarers Between 1985 and 2020
American Journal of Industrial Medicine, EarlyView.ABSTRACT Background Several studies from different countries have shown that merchant seafarers have an increased cancer risk compared to the general population. The aim of this study was to provide updated information on cancer incidence in a cohort of Swedish seafarers.
Maria Wallin +3 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.This study provides the first evidence of natural TP53 variation between tree shrew subspecies and identifies somatic TP53 mutations in spontaneous tree shrew sarcomas. The high structural and functional conservation of tree shrew p53 with humans supports its utility as a relevant model for TP53‐related cancer research.
Yingying Cao +4 more
wiley +1 more source
Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility
Cadernos de Saúde Pública, 2002 Epidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered ...
Hatagima Ana
doaj
Cancer prevention: epidemiology and perspectives.
, 1999 Following increases up until the late 1980s, some decline in cancer mortality has been observed in North America and in Western Europe. Approximately half the decline can be attributed to the levelling off in lung and other tobacco-related cancer ...
Levi, F.
core +1 more source
Наука и инновации в медицинеAim: to identify patterns of lung cancer incidence in the population of the Republic of Tatarstan and its dependence on air pollution and the cyclicity of solar activity. Material and methods. The following data were used as initial data: data on lung
Bulat I. Gataullin +3 more
doaj +1 more source
Cigarette-Specific Carcinogen Induces Stabilization of DNA methyltransferases through AKT/GSK3β/βTrCP Pathway in Lung Cancer [PDF]
, 2011 [[abstract]]Background: Most lung cancer cases are caused by cigarette-specific carcinogens, such as nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). Previous studies have shown that NNK induces promoter hypermethylation of several tumor
Yi-Shuan Hsieh, 謝翊萱
core
Abstract 5742: Identifying likely breast carcinogens using complementary mechanistic approaches
, 2017 Many commercial chemicals and environmental pollutants show chemical or mechanistic similarity with known breast carcinogens such as ionizing radiation, hormones, alcohol, and tobacco. Regulatory agencies like the US Environmental Protection Agency (EPA)
Ruthann A. Rudel +3 more
core +1 more source
Environment InternationalCancer hazard identification is the first step in preventing cancer. Robust and transparent methods for rigorous interrogation of published research are vital for a high-quality assessment of the scientific evidence resulting in cancer hazard ...
RM. Lunn +15 more
doaj +1 more source
Cancer Biology & Medicine, 2019 Each year there will be an estimated 2.1 million new lung cancer cases and 1.8 million lung cancer deaths worldwide. Tobacco smoke is the No.1 risk factors of lung cancer, accounting for > 85% lung cancer deaths. Air pollution, or haze, comprises ambient
Guangbiao Zhou
doaj +1 more source