Results 91 to 100 of about 118,473 (208)

Effects of common image manipulations on diagnostic performance in digital pathology: human study [PDF]

, 2013
A very recent work of Ref.[1] studied the effects of image manipulation and image degradation on the perceived attributes of image quality (IQ) of digital pathology slides.
Kumcu, Asli, Marchessoux, Cedric, Philips, Wilfried, Platisa, Ljiljana, Van Brantegem, Leen, Vansteenkiste, Ewout   +5 more
core  

Coordination of oxysterol binding protein 1 and VAP-A/B modulates the generation of cholesterol and viral inclusion bodies to promote grass carp reovirus replication

Frontiers in Immunology
Similar to other RNA viruses, grass carp reovirus, the causative agent of the hemorrhagic disease, replicates in cytoplasmic viral inclusion bodies (VIBs), orchestrated by host proteins and lipids.
Jia Qi Li, Jia Qi Li, Jie Zhang, Jie Zhang, Yang Chen, Yang Chen, Tao Le, Ming Xian Chang, Ming Xian Chang   +8 more
doaj   +1 more source

CRISPR/Cas9 mutagenesis reveals an essential role of PI4KB in promoting growth and resisting hemorrhagic disease caused by GCRV-II infection in juvenile grass carp

Water Biology and Security
Few studies have reported obtaining grass carp resistant to hemorrhagic disease via gene editing in commercial fish. Here, we demonstrate that the expression and activity of grass carp PI4KB (gcPI4KB) are vital for GCRV-I and GCRV-II replication.
Jie Zhang, Liqiang Zhang, Xiaoman Wu, Minhui Tao, Yang Chen, Mingxian Chang   +5 more
doaj   +1 more source

PABP-driven secondary condensed phase within RSV inclusion bodies activates viral mRNAs for ribosomal recruitment

Virologica Sinica
Inclusion bodies (IBs) of respiratory syncytial virus (RSV) are formed by liquid-liquid phase separation (LLPS) and contain internal structures termed "IB-associated granules" (IBAGs), where anti-termination factor M2-1 and viral mRNAs are concentrated. However, the mechanism of IBAG formation and the physiological function of IBAGs are unclear.
Qiang Zhang, Hanzhe Ye, Cong Liu, Haiwu Zhou, Mingbin He, Xiaodong Liang, Yu Zhou, Kun Wang, Yali Qin, Zhifei Li, Mingzhou Chen   +10 more
openaire   +2 more sources

Detection and identification of white spot syndrome virus (WSSV) and infectious hypodermal and hematopoietic necrosis virus (IHHNV) of Litopenaus vannamei from Bushehr and Sistan and Baloochestan provinces (Iran), during 2009-2010 [PDF]

, 2011
The first time the white spot disease (WSD) and IHHNV were reported in Iran was in 2004 and 2008, respectively in Bushehr Province. In Sistan and Balochestan province only the WSD was reported in 2008.The aim of this study was detecting these two viral ...
Afsharnasab, M., Dashtiannasab, A., Jalali Jafari, B., Motalebi, A.A., Pazir, M.K., Sharifpour, I.   +5 more
core  

Molecular dynamics study of T=3 capsid assembly

, 2018
Molecular dynamics simulation is used to model the self-assembly of polyhedral shells containing 180 trapezoidal particles that correspond to the T=3 virus capsid.
Rapaport, D. C.
core   +1 more source

Cylindrical inclusion protein of chilli veinal mottle virus promotes elevated viral titers of pod pepper vein yellows virus

Phytopathology Research
Mixed viral infections occur commonly in field plants. Such co-infections can lead to elevated titers of one or both viruses, potentially exacerbating symptom severity.
Shan Bu, Qionglian Wan, Lujia Wang, Shaoxiang Wang, Jian Wu, Yige Ma, Xiaohan Mo, Fei Yan, Jiejun Peng   +8 more
doaj   +1 more source

Transgenic resistance to PMTV and PVA provides novel insights to viral long-distance movement [PDF]

, 2005
The studies in this thesis describe forms of transgenic resistance to plant viruses and how they can be used for studying viral infection cycle. S. tuberosum cv.
Germundsson, Anna
core  

Grass carp Trim47 restricts GCRV infection via SPRY domain-mediated autophagic degradation of nonstructural proteins and disruption of viral inclusion bodies

Frontiers in Immunology
Trim47, a TRIM C-VII subgroup protein characterized by a conserved SPRY domain, has been primarily studied for its ubiquitin-dependent roles in mammals.
Wei Yan, Wei Yan, Yang Chen, Yang Chen, Dong Yan, Dong Yan, Jie Zhang, Jie Zhang, Ming Xian Chang, Ming Xian Chang   +9 more
doaj   +1 more source

Mining the virome for insights into type 1 diabetes [PDF]

, 2018
Park, Arnold, Zhao, Guoyan
core   +2 more sources