Results 111 to 120 of about 38,732 (289)

A role for plant microtubules in the formation of transmission-specific inclusion bodies of Cauliflower mosaic virus

, 2009
Addendum paru dans Plant Signaling and Behavior (2009) 4 (6) p. 548-550 http://dx.doi.org/10.4161/psb.4.6.8712. Interactions between microtubules and viruses play important roles in viral infection.
Uzest, Marilyne, Blanc, Stéphane, Drucker, Martin, Gargani, Daniel, Martinière, Alexandre, Lautredou, Nicole   +5 more
core   +1 more source

A Heterologous Viral Protein Scaffold for Chimeric Antigen Design: An Example PCV2 Virus Vaccine Candidate

, 2020
Recombinant vaccines have low-cost manufacturing, regulatory requirements, and reduced side effects compared to attenuated or inactivated vaccines.
Emilio Lamazares, Fernando Gutiérrez, Angela Hidalgo, Javier González, José Saavedra, Jorge R. Toledo, Manuel Mansur, Nicolas A. Gutiérrez, Marcelo Cortez-San Martín, Claudia Altamirano, Felipe I. Espinoza, Oliberto Sánchez, Álvaro Ruiz, Carolina Mascayano   +13 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

Mumps virus Enders strain is sensitive to interferon (IFN) despite encoding a functional IFN antagonist

, 2009
Although the Enders strain of mumps virus (MuV) encodes a functional V protein that acts as an interferon (IFN) antagonist, in multi-cycle growth assays MuV Enders grew poorly in naive ('IFN-competent' Hep2) cells but grew to high titres in 'IFN ...
Rima, B K, Andrejeva, Jelena, K. Lemon, B. K. Rima, Duprex, P, W. P. Duprex, M. C. Galiano, Galiano, M, J. Andrejeva, D. F. Young, R. E. Randall, Young, D F, Lemon, K, Chen, Y-H, Y.-H. Chen, Randall, Richard Edward   +15 more
core   +1 more source

A Prospective Study of Individuals at Risk of Multiple Sclerosis Informs the Design of Primary Prevention Studies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective In multiple sclerosis, the optimal time for deploying a therapeutic intervention is before the central nervous system is damaged; given the success of trials treating the earliest stage of MS, the radiologically isolated syndrome, developing primary prevention strategies is an important next challenge.
Amy W. Laitinen, Ceren Tozlu, Tina Roostaei, Fatoumata Diallo, Kaho Onomichi, Jiyeon Son, Zongqi Xia, Philip L. De Jager   +7 more
wiley   +1 more source

Influence of Nipah virus matrix protein on the localization of viral nuclocapsids and inclusion bodies

, 2018
Zusammenfassung Das Nipahvirus (NiV) ist ein hochpathogenes, BSL-4 klassifiziertes Paramyxovirus. Das Hüll-assoziierte Matrixprotein (NiV-M) spielt eine zentrale Rolle beim Virus-Assembly und der Bildung infektiöser Viruspartikel, weil es den Kontakt ...
Ringel, Marc
core   +1 more source

Cauliflower mosaic virus, a compatible pathogen of Arabidopsis, engages three distinct defense-signaling pathways and activates rapid systemic generation of reactive oxygen species [PDF]

, 2005
We analyzed expression of marker genes for three defense pathways during infection by Cauliflower mosaic virus ( CaMV), a compatible pathogen of Arabidopsis ( Arabidopsis thaliana), using luciferase reporter transgenes and directly by measuring ...
Yun, B W, Love, A J, Love, AJ, Loake, GJ, Milner, JJ, Milner, J J, Laval, V, Loake, G J, Yun, BW   +8 more
core   +1 more source

Setting Up Shop: The Formation and Function of the Viral Factories of Cauliflower mosaic virus

Frontiers in Plant Science, 2017
Similar to cells, viruses often compartmentalize specific functions such as genome replication or particle assembly. Viral compartments may contain host organelle membranes or they may be mainly composed of viral proteins.
James E. Schoelz, Scott Leisner
doaj   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Influenza Vaccination Responses in Disabled Stroke Patients: A Single‐Center Prospective Observational Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This study aimed to investigate the immunological response to influenza vaccination, the incidence and severity of influenza infection, and the side effects of the vaccination in patients with ischemic stroke. Methods This prospective observational study was conducted between 2023 and 2024 at Ramathibodi Hospital.
Achiraya Pakngao, Sureerat Suwatcharangoon, Pintip Ngamjanyapron, Kobporn Boonnak, Thanitta Suangtamai, Porpon Rotjanapan   +5 more
wiley   +1 more source