Results 161 to 170 of about 38,732 (289)

Integrating replication kinetics and ultrastructural analysis to identify targets for optimizing rVSV bioproduction. [PDF]

Microbiol Spectr
Habisch R, Wieland JG, Soza-Ried J, Read C, Walther P, Neubauer P, Puschmann E, Dass M.   +7 more
europepmc   +1 more source

Marburg Virus Glycoprotein Is a Remarkable Virulent Factor Linked to Hemorrhagic Pathology: Evidence from Multimodal Experimental Systems

Advanced Science, EarlyView.
By integrating data from in vitro, ex vivo, and in vivo models, our research identifies the MARV glycoprotein as a remarkable hemorrhagic factor, filling a major gap in this important field. It also provides practical experimental tools for the basic research on viral pathogenesis and applied research aimed at antiviral intervention for hemorrhagic ...
Ting Yao, Hang Liu, Yanfeng Yao, Wei Deng, Jiawen Sun, Zhenyu Kang, Ashaq Ali, Chao Shan, Zhiming Yuan, Fei Deng, Hualin Wang, Yun‐Jia Ning   +11 more
wiley   +1 more source

Interstitial pneumonia associated with equid gammaherpesvirus 5 infection in 2 neonatal foals, and a retrospective study in Hokkaido, Japan. [PDF]

J Vet Diagn Invest
Ochi A, Takechi M, Fujii S, Ohno O, Kishi D, Ueno T.   +5 more
europepmc   +1 more source

GATA4‐Driven Transcription of HtrA1 Promotes Cellular Senescence in Ménière's Disease and Age‐Related Audio‐Vestibular Dysfunction

Advanced Science, EarlyView.
This study identifies the HDAC6/GATA4/HtrA1 axis as a critical driver of cellular senescence in the inner ear. GATA4 nuclear translocation, facilitated by HDAC6 downregulation, transcriptionally activates HtrA1, promoting hair cell senescence, SASP, and audio‐vestibular dysfunction in models of Ménière's disease and age‐related audio‐vestibular ...
Na Zhang, Na Li, Yan Wang, Jing Zhang, Jiahui Liu, Lei Chen, Yongdong Song, Yurong Mu, Yuechen Han, Yafeng Lyu, Xiaofei Li, Hanyue Wang, Jing Wang, Yao Lu, Zhaomin Fan, Daogong Zhang, Haibo Wang   +16 more
wiley   +1 more source

DEMONSTRATION OF VIRAL INCLUSION BODIES IN UNSTAINED TISSUE SECTIONS WITH THE AID OF THE PHASE MICROSCOPE I [PDF]

Journal of Bacteriology, 1949
J J, Angulo, O W, Richards, A L, Roque
openaire   +3 more sources

LC3B Mediated SETDB1‐Accounted Alcoholic Steatohepatitis via Lipidation‐Dependent LAP and Lipidation‐Independent Nuclear Stabilization

Advanced Science, EarlyView.
SETDB1 is progressively downregulated in ALD, correlating with disease severity. SETDB1 deficiency impairs LAP by disrupting Rubicon membrane localization, leading to defective lipid droplet clearance. Concurrently, loss of SETDB1 reduces nuclear LC3B, causing R‐loop accumulation and cGAS‐STING‐driven inflammation. Lipidated LC3B mediates LAP‐dependent
Yi Zhang, Tan Wei, Jiahang Wu, Chuixu Lin, Dongbo Zhu, Yanhui Li, Shuting Shi, Shishun Huang, Leiming Jiang, Hongzhi Wang, Meiqi Song, Pengfei Gao, Xu Wu, Mingjian Fan, Chaofeng Wei, Qian Wang, Lihui Qu, Zhigang Wang   +17 more
wiley   +1 more source

Human respiratory syncytial virus regulates the expression of interferon-stimulated genes through modulation of fibrillarin. [PDF]

Front Cell Infect Microbiol
Ulloa-Aguilar JM, Cruz-Holguin VJ, Benítez-Zeferino YR, Guzmán-Bautista ER, García-Cordero J, De Jesús-González LA, Vázquez-Martínez JA, Vázquez-Martínez ER, Herrera-Moro Huitron L, Mosqueda-Gracida A, Viveros-Rogel M, Vergara-Mendoza M, Miranda-Labra RU, León-Juárez M.   +13 more
europepmc   +1 more source

Viral inclusion bodies in polyomavirus nephropathy in renal allograft recipient

Indian Journal of Transplantation, 2012
Narayan Prasad, Dharmender Bhadauria, Manoj Jain, Vinita Agarwal, Raj Kumar Sharma, Amit Gupta, Anupama Kaul   +6 more
openaire   +1 more source

Cold Orthogonal Translation: A Psychrophilic Pyrrolysyl‐tRNA Synthetase Boosts Genetic Code Expansion in E. coli

Advanced Science, EarlyView.
ABSTRACT Orthogonal translation systems (OTSs) enable site‐specific incorporation of non‐canonical amino acids (ncAAs) and are central to genetic code expansion. Current engineering strategies typically rely on hyperstable aminoacyl tRNA synthetase (aaRS) scaffolds to tolerate destabilizing mutations required for substrate diversification.
Nikolaj G. Koch, Peter Goettig, Michael A. Nash, Juri Rappsilber, Nediljko Budisa   +4 more
wiley   +1 more source

Photo Quiz: Persistent papules in an immunocompromised child. [PDF]

J Clin Microbiol
Broadfoot BG, Mallampati S, Jackson SM, Boyanton BL.   +3 more
europepmc   +1 more source