Results 41 to 50 of about 38,732 (289)
Measles Virus Forms Inclusion Bodies with Properties of Liquid Organelles [PDF]
, 2019 Nonsegmented negative-strand RNA viruses, including measles virus (MeV), a member of the Paramyxoviridae family, are assumed to replicate in cytoplasmic inclusion bodies.
Samuel, Charles E +3 more
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Pur-Alpha Induces JCV Gene Expression and Viral Replication by Suppressing SRSF1 in Glial Cells. [PDF]
PLoS ONE, 2016 OBJECTIVE:PML is a rare and fatal demyelinating disease of the CNS caused by the human polyomavirus, JC virus (JCV), which occurs in AIDS patients and those on immunosuppressive monoclonal antibody therapies (mAbs).
Ilker Kudret Sariyer +3 more
doaj +1 more source
Human Respiratory Syncytial Virus Infection in a Human T Cell Line Is Hampered at Multiple Steps
Viruses, 2021 Human respiratory syncytial virus (HRSV) is the most frequent cause of severe respiratory disease in children. The main targets of HRSV infection are epithelial cells of the respiratory tract, and the great majority of the studies regarding HRSV ...
Ricardo de Souza Cardoso +10 more
doaj +1 more source
Evasion of Antiviral Immunity through Sequestering of TBK1/IKKε/IRF3 into Viral Inclusion Bodies [PDF]
Journal of Virology, 2014 ABSTRACT Cells are equipped with pattern recognition receptors (PRRs) such as the Toll-like and RIG-I-like receptors that mount innate defenses against viruses. However, viruses have evolved multiple strategies to evade or thwart host antiviral responses.
Xiaodong, Wu +8 more
openaire +2 more sources
Nature Communications, 2023 Human metapneumovirus (HMPV) is a major cause of respiratory illness in young children. The HMPV polymerase (L) binds an obligate cofactor, the phosphoprotein (P).
Jack D. Whitehead +7 more
doaj +1 more source
Human Cytomegalovirus. Studies on the Mechanism of Viral Gytopathology and Inclusion Body Formation.
Experimental Biology and Medicine, 1967 SummaryWhen cultured human fetal fi-broblasts were infected by human cytomegalo-virus, virus-induced morphologic changes consisting of cytopathology, intracytoplasmic and intranuclear inclusion bodies developed during a 72-hour period. Thus, in this system, virus-induced cell changes followed closely upon viral multiplication.
R M, McAllister +2 more
openaire +2 more sources
, 2009 This work was supported by the Wellcome Trust.Although the replication cycle of parainfluenza virus type 5 (PIV5) is initially severely impaired in cells in an interferon (IFN)-induced antiviral state, the virus still targets STAT1 for degradation.
Carlos, T S +4 more
core +1 more source
Upon Infection, Cellular WD Repeat-Containing Protein 5 (WDR5) Localizes to Cytoplasmic Inclusion Bodies and Enhances Measles Virus Replication [PDF]
, 2018 Replication of negative-strand RNA viruses occurs in association with discrete cytoplasmic foci called inclusion bodies. Whereas inclusion bodies represent a prominent subcellular structure induced by viral infection, our knowledge of the cellular ...
Pfaller, Christian K +11 more
core +1 more source
Viruses, 2021 Liquid–liquid phase separation (LLPS) represents a major physiochemical principle to organize intracellular membrane-less structures. Studies with non-segmented negative-sense (NNS) RNA viruses have uncovered a key role of LLPS in the formation of viral ...
Justin M. Su +3 more
doaj +1 more source
Nipah Virus Impairs Autocrine IFN Signaling by Sequestering STAT1 and STAT2 into Inclusion Bodies
, 2023 Nipah virus (NiV) is an emerging zoonotic paramyxovirus that causes fatal infections in humans. As with most disease-causing viruses, the pathogenic potential of NiV is linked to its ability to block antiviral responses, e.g., by antagonizing IFN ...
Nico Becker, Andrea Maisner
core +1 more source