N6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication
Frontiers in Cell and Developmental Biology, 2021 N6-methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV).
Fabian Figueroa +15 more
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Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies. [PDF]
PLoS Pathogens, 2009 Human neurons express the innate immune response receptor, Toll-like receptor 3 (TLR3). TLR3 levels are increased in pathological conditions such as brain virus infection.
Pauline Ménager +8 more
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Viral Inclusion Bodies in Tracheobronchial Epithelium of Asymptomatic Subjects [PDF]
Chest, 1976 During a survey conducted for the cytodiagnosis of early bronchogenic carcinoma, cytoplasmic viral inclusion bodies were found sporadically in tracheobronchial smears of asymtomatic patients of both sexes (ages ranging from 18 to 80 years) undergoing general endotracheal anesthesia for surgery.
Katz, Judith S. +2 more
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Cytomegalovirus-associated esophageal ulcer in an immunocompetent infant: When should ganciclovir be administered? [PDF]
Korean Journal of Pediatrics, 2012 Cytomegalovirus (CMV)-associated esophageal ulcer is rare in immunocompetent infants. The presence of inclusion bodies and immunohistochemical staining for CMV in biopsy specimens obtained during esophagogastroduodenoscopy (EGD) indicate that such ulcers
Hyo-Jeong Jang +2 more
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Entrapment of viral capsids in nuclear PML cages is an intrinsic antiviral host defense against varicella-zoster virus. [PDF]
, 2011 The herpesviruses, like most other DNA viruses, replicate in the host cell nucleus. Subnuclear domains known as promyelocytic leukemia protein nuclear bodies (PML-NBs), or ND10 bodies, have been implicated in restricting early herpesviral gene expression.
Baiker Armin +28 more
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Viruses, 2020 Members of the Reoviridae family assemble virus factories within the cytoplasm of infected cells to replicate and assemble virus particles. Bluetongue virus (BTV) forms virus inclusion bodies (VIBs) that are aggregates of viral RNA, certain viral ...
Bjorn-Patrick Mohl +4 more
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Formation of large viroplasms and virulence of Cauliflower mosaic virus in turnip plants depend on the N-terminal EKI sequence of viral protein TAV. [PDF]
PLoS ONE, 2017 Cauliflower mosaic virus (CaMV) TAV protein (TransActivator/Viroplasmin) plays a pivotal role during the infection cycle since it activates translation reinitiation of viral polycistronic RNAs and suppresses RNA silencing.
Angèle Geldreich +8 more
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The Cellular Protein CAD is Recruited into Ebola Virus Inclusion Bodies by the Nucleoprotein NP to Facilitate Genome Replication and Transcription [PDF]
, 2020 Ebola virus (EBOV) is a zoonotic pathogen causing severe hemorrhagic fevers in humans and non-human primates with high case fatality rates. In recent years, the number and extent of outbreaks has increased, highlighting the importance of better ...
Brandt, Janine +9 more
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Advancing the pathologic phenotype of giant axonal neuropathy: early involvement of the ocular lens
Orphanet Journal of Rare Diseases, 2019 Giant axonal neuropathy (GAN; ORPHA: 643; OMIM# 256850) is a rare, hereditary, pediatric neurodegenerative disorder associated with intracellular accumulations of intermediate filaments (IFs).
Diane Armao +5 more
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CRYSTALLINE INTRANUCLEAR INCLUSIONS IN THE RENAL TUBULAR EPITHELIUM OF DOGS [PDF]
Assiut Veterinary Medical Journal, 1987 Intranuclear inclusion bodies with characteristic shape were found in renal tubuler epithelium of dogs. These inclusions were found in 20 out of 50 animals postmortally examined in faculty of Vet. Med. Assiut University.
M.K. IBRAHIM, A.Z. MAHMOUD, A. NAFADY
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