Results 51 to 60 of about 38,732 (289)
RSV hijacks cellular protein phosphatase 1 to regulate M2-1 phosphorylation and viral transcription.
PLoS Pathogens, 2018 Respiratory syncytial virus (RSV) RNA synthesis occurs in cytoplasmic inclusion bodies (IBs) in which all the components of the viral RNA polymerase are concentrated.
Charles-Adrien Richard +10 more
doaj +1 more source
Folding and Oligomerization of the gp2b/gp3/gp4 Spike Proteins of Equine Arteritis Virus in Vitro
Viruses, 2012 Equine arteritis virus (EAV) is a small, positive-stranded RNA virus. The glycoproteins gp2b, gp3 and gp4 form a heterotrimer in the viral envelope, which is required for cell entry of EAV.
Aleksander Kabatek, Michael Veit
doaj +1 more source
Frontiers in Immunology, 2018 In the search for an eminently practical strategy to develop immunostimulants and vaccines for farmed fish, we have devised recombinant viral antigens presented as “nanopellets” (NPs).
Rosemary Thwaite +8 more
doaj +1 more source
A second cauliflower mosaic virus gene product influences the structure of the viral inclusion body [PDF]
The EMBO Journal, 1984 We have used electron microscopy of thin sections and experiments on isolated viroplasms to compare the properties of four strains of cauliflower mosaic virus (CaMV), three of which were partially or completely deleted in open reading frame (ORF) II. Our results confirm that this gene is required for aphid transmissibility and show that the product of ...
/Givord, Louise +6 more
openaire +3 more sources
Cardiac involvement in human rabies: case report
Revista do Instituto de Medicina Tropical de São Paulo, 1985 A case of human rabies with cardiac involvement and viral inclusion bodies in the heart is presented. The Negri bodies were found in the Schwann cells of the right epicardial atrium, with secondary mononuclear cells inflammation.
Carlos Floriano de Morais +1 more
doaj +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Ebola virus recruits the nuclear RNA export factor NXF1 for viral mRNA export from inclusion bodies
, 2022 Ebola virus (EBOV) causes severe haemorrhagic fevers in humans with limited treatment options. Virus-host interactions are promising targets for the development of broadly acting antivirals, but knowledge of host factors involved in the EBOV life cycle ...
core
Cell Reports, 2019 Summary: Many positive-strand RNA viruses remodel the endomembrane to form specialized replication organelles. However, knowledge regarding whether negative-strand RNA viruses take advantage of intracellular membranes for replication is limited.
Zhifei Li +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
, 2013 This work was supported by the Wellcome Trust.Interferon (IFN) induces an antiviral state in cells that results in alterations of the patterns and levels of parainfluenza virus type 5 (PIV5) transcripts and proteins.
Goodbourn, S +11 more
core +1 more source