Results 11 to 20 of about 82,636 (249)

Coordination of oxysterol binding protein 1 and VAP-A/B modulates the generation of cholesterol and viral inclusion bodies to promote grass carp reovirus replication

Frontiers in Immunology
Similar to other RNA viruses, grass carp reovirus, the causative agent of the hemorrhagic disease, replicates in cytoplasmic viral inclusion bodies (VIBs), orchestrated by host proteins and lipids.
Jia Qi Li, Jia Qi Li, Jie Zhang, Jie Zhang, Yang Chen, Yang Chen, Tao Le, Ming Xian Chang, Ming Xian Chang   +8 more
doaj   +3 more sources

PABP-driven secondary condensed phase within RSV inclusion bodies activates viral mRNAs for ribosomal recruitment

Virologica Sinica
Inclusion bodies (IBs) of respiratory syncytial virus (RSV) are formed by liquid-liquid phase separation (LLPS) and contain internal structures termed "IB-associated granules" (IBAGs), where anti-termination factor M2-1 and viral mRNAs are concentrated. However, the mechanism of IBAG formation and the physiological function of IBAGs are unclear.
Mingzhou Chen
exaly   +3 more sources

N6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication

Frontiers in Cell and Developmental Biology, 2021
N6-methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV).
Fabian Figueroa, Alonso Vega-Gibson, Joseline Catrileo, Aracelly Gaete-Argel, Aracelly Gaete-Argel, Sebastian Riquelme-Barrios, Sebastian Riquelme-Barrios, Luis Antonio Alonso-Palomares, Luis Antonio Alonso-Palomares, Lorena I. Tapia, Lorena I. Tapia, Fernando Valiente-Echeverría, Fernando Valiente-Echeverría, Ricardo Soto-Rifo, Ricardo Soto-Rifo, Monica L. Acevedo   +15 more
doaj   +1 more source

Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies. [PDF]

PLoS Pathogens, 2009
Human neurons express the innate immune response receptor, Toll-like receptor 3 (TLR3). TLR3 levels are increased in pathological conditions such as brain virus infection.
Pauline Ménager, Pascal Roux, Françoise Mégret, Jean-Pierre Bourgeois, Anne-Marie Le Sourd, Anne Danckaert, Mireille Lafage, Christophe Préhaud, Monique Lafon   +8 more
doaj   +1 more source

Viral Inclusion Bodies in Tracheobronchial Epithelium of Asymptomatic Subjects [PDF]

Chest, 1976
During a survey conducted for the cytodiagnosis of early bronchogenic carcinoma, cytoplasmic viral inclusion bodies were found sporadically in tracheobronchial smears of asymtomatic patients of both sexes (ages ranging from 18 to 80 years) undergoing general endotracheal anesthesia for surgery.
Katz, Judith S., Chalon, Jack, Turndorf, Herman   +2 more
openaire   +2 more sources

The N-Terminal of Aquareovirus NS80 Is Required for Interacting with Viral Proteins and Viral Replication. [PDF]

PLoS ONE, 2016
Reovirus replication and assembly occurs within viral inclusion bodies that formed in specific intracellular compartments of cytoplasm in infected cells.
Jie Zhang, Hong Guo, Qingxiu Chen, Fuxian Zhang, Qin Fang   +4 more
doaj   +1 more source

Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons. [PDF]

, 2017
Inclusion body disease (IBD) is an infectious disease originally described in captive snakes. It has traditionally been diagnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurological, gastrointestinal, and ...
Boback, Scott M, DeRisi, Joseph L, Drazenovich, Tracy, Garcia, Valentina E, Hawkins, Michelle G, Hoon-Hanks, Laura L, Keel, M Kevin, Layton, Marylee L, Sanchez-Migallon Guzman, David, Stenglein, Mark D   +9 more
core   +1 more source

Unravelling the structure of viral replication complexes at super-resolution

Frontiers in Plant Science, 2013
During infection, many RNA viruses produce characteristic inclusion bodies that contain both viral and host components. These structures were first described over a century ago and originally termed ‘X bodies’, as their function was not immediately ...
Olga eLinnik, Johannes eLiesche, Jens eTilsner, Jens eTilsner, Karl eOparka   +4 more
doaj   +1 more source

Detection of arenavirus in a peripheral odontogenic fibromyxoma in a red tail boa (Boa constrictor constrictor) with inclusion body disease [PDF]

, 2015
A captive bred red tail boa (Boa constrictor constrictor) was presented with a large intraoral mass originating from the buccal gingiva, attached to the right dentary teeth row.
Ducatelle, Richard, Hellebuyck, Tom, Martel, An, Pasmans, Frank, Saey, Veronique   +4 more
core   +1 more source

Cellular Casein Kinase 2 and Protein Phosphatase 2A Modulate Replication Site Assembly of Bluetongue Virus. [PDF]

, 2016
A number of cytoplasmic replicating viruses produce cytoplasmic inclusion bodies or protein aggregates; however, a hallmark of viruses of the Reoviridae family is that they utilize these sites for purposes of replication and capsid assembly, functioning ...
Mohl, Bjorn-Patrick, Roy, Polly
core   +1 more source