Morphogenesis and functional organization of viral inclusion bodies
Cell Insight, 2023 Eukaryotic viruses are obligate intracellular parasites that rely on the host cell machinery to carry out their replication cycle. This complex process involves a series of steps, starting with virus entry, followed by genome replication, and ending with
Zhifei Li +4 more
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Ebola virus sequesters IRF3 in viral inclusion bodies to evade host antiviral immunity
eLife, 2023 Viral inclusion bodies (IBs) commonly form during the replication of Ebola virus (EBOV) in infected cells, but their role in viral immune evasion has rarely been explored.
Lin Zhu +12 more
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Grass carp reovirus VP56 and VP35 induce formation of viral inclusion bodies for replication
iScienceSummary: Viral inclusion bodies (VIBs) are subcellular structures required for efficient viral replication. How type II grass carp reovirus (GCRV-II), the mainly prevalent strain, forms VIBs is unknown.
Chu Zhang +4 more
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N6 -Methyladenosine Negatively Regulates Human Respiratory Syncytial Virus Replication
Frontiers in Cell and Developmental Biology, 2021 N6-methyladenosine (m6A) is the most abundant internal modification described in eukaryotic mRNA and several viral RNA including human respiratory syncytial virus (HRSV).
Fabian Figueroa +15 more
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Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies. [PDF]
PLoS Pathogens, 2009 Human neurons express the innate immune response receptor, Toll-like receptor 3 (TLR3). TLR3 levels are increased in pathological conditions such as brain virus infection.
Pauline Ménager +8 more
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Viral Inclusion Bodies in Tracheobronchial Epithelium of Asymptomatic Subjects [PDF]
Chest, 1976 During a survey conducted for the cytodiagnosis of early bronchogenic carcinoma, cytoplasmic viral inclusion bodies were found sporadically in tracheobronchial smears of asymtomatic patients of both sexes (ages ranging from 18 to 80 years) undergoing general endotracheal anesthesia for surgery.
Katz, Judith S. +2 more
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Cytomegalovirus-associated esophageal ulcer in an immunocompetent infant: When should ganciclovir be administered? [PDF]
Korean Journal of Pediatrics, 2012 Cytomegalovirus (CMV)-associated esophageal ulcer is rare in immunocompetent infants. The presence of inclusion bodies and immunohistochemical staining for CMV in biopsy specimens obtained during esophagogastroduodenoscopy (EGD) indicate that such ulcers
Hyo-Jeong Jang +2 more
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The N-Terminal of Aquareovirus NS80 Is Required for Interacting with Viral Proteins and Viral Replication. [PDF]
PLoS ONE, 2016 Reovirus replication and assembly occurs within viral inclusion bodies that formed in specific intracellular compartments of cytoplasm in infected cells.
Jie Zhang +4 more
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Unravelling the structure of viral replication complexes at super-resolution
Frontiers in Plant Science, 2013 During infection, many RNA viruses produce characteristic inclusion bodies that contain both viral and host components. These structures were first described over a century ago and originally termed ‘X bodies’, as their function was not immediately ...
Olga eLinnik +4 more
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Viruses, 2020 Members of the Reoviridae family assemble virus factories within the cytoplasm of infected cells to replicate and assemble virus particles. Bluetongue virus (BTV) forms virus inclusion bodies (VIBs) that are aggregates of viral RNA, certain viral ...
Bjorn-Patrick Mohl +4 more
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