Results 91 to 100 of about 1,278,840 (295)

Progressive myoclonus epilepsy associated with neuroserpin inclusion bodies (neuroserpinosis) [PDF]

, 2016
Familial encephalopathy with neuroserpin inclusion bodies (FENIB) is a conformational proteinopathy characterised by neuronal inclusion bodies composed of the serine protease inhibitor (SERPIN), neuroserpin.
Crowther, DC, Lomas, DA, Roussel, BD
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

A cell culture system for the induction of Mallory bodies: Mallory bodies and aggresomes represent different types of inclusion bodies [PDF]

, 2018
Mallory bodies (MBs) represent keratin-rich inclusion bodies observed in human alcoholic liver disease and in several chronic non-alcoholic liver diseases.
Guhl, Bruno, Hirano, Kiyoko, Roth, Jürgen, Ziak, Martin   +3 more
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Successful production of recombinant buckwheat cysteine-rich aspartic protease in Escherichia coli [PDF]

Journal of the Serbian Chemical Society, 2009
Herein, the expression of recombinant cysteine-rich atypical buckwheat (Fagopyrum esculentum) aspartic protease (FeAPL1) in five Escherichia coli strains differing in their expression capabilities is presented.
MIRA D. MILISAVLJEVIĆ, DRAŽEN R. PAPIĆ, GORDANA S. TIMOTIJEVIĆ, VESNA R. MAKSIMOVIĆ   +3 more
doaj  

A variant of green fluorescent protein exclusively deposited to active intracellular inclusion bodies [PDF]

, 2014
Background: Inclusion bodies (IBs) were generally considered to be inactive protein deposits and did not hold any attractive values in biotechnological applications.
A Crameri, A MaHam, A Villaverde, A Villaverde, AK Upadhyay, AL Fink, AL Fink, D Esposito, DJ Ravnic, DMGN Worrall, E Garcia-Fruitos, E Vázquez, F Baneyx, F Librizzi, G Raghunathan, G Raghunathan, G Raghunathan, G-F Elena, GA Bowden, Ganapathiraman Munussami, Govindan Raghunathan, H-S Seo, Hyojin Moon, Hyun-jong Paik, J Nahalka, J Nahalka, J-D Pedelacq, KR Kim, L Wang, L Wang, M Biancalana, M Carrio, M Morell, MM Carrio, N Soundrarajan, NS de Groot, P Borges, R Sabate, RY Tsien, S Nagasundarapandian, S Peternel, S-TD Hsu, Sebyung Kang, Seong Soo A An, Sun-Gu Lee, TC Vessoni Penna, W Wu, Y Ito, Yong-Sung Kim, Z Huang   +49 more
core   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Aerobic growth of Rhodococcus aetherivorans BCP1 using selected naphthenic acids as the sole carbon and energy sources [PDF]

, 2018
Naphthenic acids (NAs) are an important group of toxic organic compounds naturally occurring in hydrocarbon deposits. This work shows that Rhodococcus aetherivorans BCP1 cells not only utilize a mixture of eight different NAs (8XNAs) for growth but they ...
Cappelletti M., Crognale S., Demeter M. A., Fedi S., Ferreri C., Milazzo G., Petruccioli M., Piacenza E., Presentato A., Sansone A., Steinbuchel A., Turner R. J., Zannoni D.   +12 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Chemical Assistance in Refolding of Bacterial Inclusion Bodies

Biochemistry Research International, 2011
Escherichia coli is one of the most widely used hosts for the production of recombinant proteins but insoluble expression of heterologous proteins is a major bottleneck in production of recombinant proteins in E. coli.
Mona Alibolandi, Hasan Mirzahoseini
doaj   +1 more source