Nuclear pore pathology underlying multisystem proteinopathy type 3‐related inclusion body myopathy [PDF]
, 2023 Rumiko Izumi +10 more
openalex +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Feasibility of modifying the high resolution infrared radiation sounder (HIRS/2) for measuring spectral components of Earth radiation budget [PDF]
The concept of adding four spectral channels to the 20 channel HIRS/2 instrument for the purpose of determining the origin and profile of radiant existence from the Earth's atmosphere is considered. Methods of addition of three channels at 0.5, 1.0 and 1.
Holman, K. A., Koenig, E. W.
core +1 more source
High-quality patents for emerging science and technology through external actors: community scientific experts and knowledge societies [PDF]
, 2010 This article explores one type of administrative mechanism to achieve high-quality patents: Article 115 of the European Patent Convention, which permits the inclusion of third parties to provide input to the prior art search and to communicate relevant ...
Groenendijk, Nico +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FaCE: a tool for Three Body Faddeev calculations with core excitation
, 2004 FaCE is a self contained programme, with namelist input, that solves the three body Faddeev equations. It enables the inclusion of excitation of one of the three bodies, whilst the other two remain inert.
Al-Khalili +22 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
A role for plant microtubules in the formation of transmission‐specific inclusion bodies of Cauliflower mosaic virus [PDF]
, 2008 Alexandre Martinière +5 more
openalex +1 more source
Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species
Scientific Reports, 2012 The identities of toxic aggregate species in Huntington's disease pathogenesis remain ambiguous. While polyQ-expanded huntingtin (Htt) is known to accumulate in compact inclusion bodies inside neurons, this is widely thought to be a protective coping ...
S. Sahl +4 more
semanticscholar +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source