Results 41 to 50 of about 7,022,792 (370)

Penicillin kills chlamydia following the fusion of bacteria with Lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice [PDF]

open access: yes, 2013
The obligate intracellular bacterium Chlamydia exists as two distinct forms. Elementary bodies (EBs) are infectious and extra-cellular, whereas reticulate bodies (RBs) replicate within a specialized intracellular compartment termed an ‘inclusion ...
Delarbre, C.   +7 more
core   +5 more sources

Pustulonodular cytomegalovirus infection

open access: yesHuman Pathology: Case Reports, 2020
The cutaneous manifestations of cytomegalovirus (CMV) vary and may be difficult to identify histopathologically. Cutaneous CMV lesions are relatively rare and may be overlooked as infection usually presents in visceral organs, particularly the ...
Mona Deerwester   +2 more
doaj   +1 more source

Functional organization of cytoplasmic inclusion bodies in cells infected by respiratory syncytial virus

open access: yesNature Communications, 2017
Infection of cells by respiratory syncytial virus induces the formation of cytoplasmic inclusion bodies (IBs) where all the components of the viral RNA polymerase complex are concentrated.
V. Rincheval   +9 more
semanticscholar   +1 more source

Targeting Antitumoral Proteins to Breast Cancer by Local Administration of Functional Inclusion Bodies

open access: yesAdvancement of science, 2019
Two structurally and functionally unrelated proteins, namely Omomyc and p31, are engineered as CD44‐targeted inclusion bodies produced in recombinant bacteria.
Mireia Pesarrodona   +15 more
semanticscholar   +1 more source

Recovering time-dependent inclusion in heat conductive bodies by a dynamical probe method [PDF]

open access: yes, 2015
We consider an inverse boundary value problem for the heat equation $\partial_t v = {\rm div}_x\,(\gamma\nabla_x v)$ in $(0,T)\times\Omega$, where $\Omega$ is a bounded domain of $R^3$, the heat conductivity $\gamma(t,x)$ admits a surface of ...
Poisson, Olivier
core   +3 more sources

Bacterial inclusion bodies are industrially exploitable amyloids

open access: yesFEMS Microbiology Reviews, 2018
Understanding the structure, functionalities and biology of functional amyloids is an issue of emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria during protein production processes, have emerged as unanticipated,
A. de Marco   +9 more
semanticscholar   +1 more source

Enhanced Production Process of Recombinant Mature Serratiopeptidase in Escherichia coli Using Fed-Batch Culture by Self-Proteolytic Activity of Fusion Protein

open access: yesFermentation, 2022
Microbial enzymes are increasingly finding applications as therapeutics due to their targeted activity and minimal side effects. Serratiopeptidase, also known as a miracle enzyme, has already proved its potential as an anti-inflammatory, mucolytic ...
Pooja Doshi   +6 more
doaj   +1 more source

Perspectives of inclusion bodies for bio-based products: curse or blessing?

open access: yesApplied Microbiology and Biotechnology, 2018
The bacterium Escherichia coli is a major host for recombinant protein production of non-glycosylated products. Depending on the expression strategy, the recombinant protein can be located intracellularly, which often leads to protein aggregates inside ...
C. Slouka   +3 more
semanticscholar   +1 more source

Efficient Autotransporter-Mediated Extracellular Secretion of a Heterologous Recombinant Protein by Escherichia coli

open access: yesMicrobiology Spectrum, 2023
The autotransporter protein secretion system has been used previously to target the secretion of heterologous proteins to the bacterial cell surface and the extracellular milieu at the laboratory scale.
Irene Beriotto   +12 more
doaj   +1 more source

Suppression of the IFN-α and -β Induction through Sequestering IRF7 into Viral Inclusion Bodies by Nonstructural Protein NSs in Severe Fever with Thrombocytopenia Syndrome Bunyavirus Infection

open access: yesJournal of Immunology, 2018
Induction of type I IFNs during viral infection is crucial for host defense. IRF 3 and IRF7 play a critical role as key transcription factors in the activation of the IFN induction.
Ye Hong   +7 more
semanticscholar   +1 more source

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