Results 41 to 50 of about 7,614,909 (324)

Pustulonodular cytomegalovirus infection

open access: yesHuman Pathology: Case Reports, 2020
The cutaneous manifestations of cytomegalovirus (CMV) vary and may be difficult to identify histopathologically. Cutaneous CMV lesions are relatively rare and may be overlooked as infection usually presents in visceral organs, particularly the ...
Mona Deerwester   +2 more
doaj   +1 more source

The Poly-Histidine Tag H6 Mediates Structural and Functional Properties of Disintegrating, Protein-Releasing Inclusion Bodies

open access: yesPharmaceutics, 2022
The coordination between histidine-rich peptides and divalent cations supports the formation of nano- and micro-scale protein biomaterials, including toxic and non-toxic functional amyloids, which can be adapted as drug delivery systems.
Julieta María Sánchez   +10 more
doaj   +1 more source

Bacterial Inclusion Bodies: Discovering Their Better Half.

open access: yesTIBS -Trends in Biochemical Sciences. Regular ed, 2017
Bacterial inclusion bodies (IBs) are functional, non-toxic amyloids occurring in recombinant bacteria showing analogies with secretory granules of the mammalian endocrine system.
U. Rinas   +5 more
semanticscholar   +1 more source

Penicillin kills chlamydia following the fusion of bacteria with Lysosomes and prevents genital inflammatory lesions in C. muridarum-infected mice [PDF]

open access: yes, 2013
The obligate intracellular bacterium Chlamydia exists as two distinct forms. Elementary bodies (EBs) are infectious and extra-cellular, whereas reticulate bodies (RBs) replicate within a specialized intracellular compartment termed an ‘inclusion ...
Delarbre, C.   +7 more
core   +5 more sources

Isolation of cell-free bacterial inclusion bodies

open access: yesMicrobial Cell Factories, 2010
Background Bacterial inclusion bodies are submicron protein clusters usually found in recombinant bacteria that have been traditionally considered as undesirable products from protein production processes.
Rodríguez-Carmona Escarlata   +4 more
doaj   +1 more source

Bacterial inclusion bodies are industrially exploitable amyloids

open access: yesFEMS Microbiology Reviews, 2018
Understanding the structure, functionalities and biology of functional amyloids is an issue of emerging interest. Inclusion bodies, namely protein clusters formed in recombinant bacteria during protein production processes, have emerged as unanticipated,
A. de Marco   +9 more
semanticscholar   +1 more source

Perspectives of inclusion bodies for bio-based products: curse or blessing?

open access: yesApplied Microbiology and Biotechnology, 2018
The bacterium Escherichia coli is a major host for recombinant protein production of non-glycosylated products. Depending on the expression strategy, the recombinant protein can be located intracellularly, which often leads to protein aggregates inside ...
C. Slouka   +3 more
semanticscholar   +1 more source

Cytomegalovirus-associated esophageal ulcer in an immunocompetent infant: When should ganciclovir be administered? [PDF]

open access: yes, 2012
Cytomegalovirus (CMV)-associated esophageal ulcer is rare in immunocompetent infants. The presence of inclusion bodies and immunohistochemical staining for CMV in biopsy specimens obtained during esophagogastroduodenoscopy (EGD) indicate that such ulcers
Ae Suk Kim   +11 more
core   +1 more source

Solubilization of inclusion bodies: insights from explainable machine learning approaches

open access: yesFrontiers in Chemical Engineering, 2023
We present explainable machine learning approaches for gaining deeper insights into the solubilization processes of inclusion bodies. The machine learning model with the highest prediction accuracy for the protein yield is further evaluated with regard ...
Cornelia Walther   +12 more
doaj   +1 more source

Custom made inclusion bodies: impact of classical process parameters and physiological parameters on inclusion body quality attributes

open access: yesMicrobial Cell Factories, 2018
BackgroundThe bacterium E. coli is a major host for recombinant protein production of non-glycosylated products. Depending on the expression strategy, the recombinant protein can be located intracellularly. In many cases the formation of inclusion bodies
C. Slouka   +7 more
semanticscholar   +1 more source

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