Results 101 to 110 of about 1,292,732 (363)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Inclusive Education in Armenia [PDF]

Armenian Folia Anglistika, 2019
The article is on the Inclusive Education in general and the status of it in the Republic of Armenia. It mainly covers the notion of Inclusive Education, the functioning model of education in Armenia, its necessity and importance to be applied in many schools of Armenia.
openaire   +2 more sources

Supporting inclusive classrooms: can Western approaches to teaching be applied within an Indian context? [PDF]

, 2013
As there has been an increase in Western Higher Education Institutions delivering their degree programmes in the emerging economies of Asia so have concerns been expressed that these initiatives may become a form of ‘colonialism’ seen as offering ...
Doveston, Mary, Jament, Johnson, Rajanahally, Jayashree, Rose, Richard, Visser, John   +4 more
core  

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

The Ethic of Care and Inclusive Education

, 2018
This article deals with the ethic of care in education, with a specific focus on classrooms that include students with disabilities. After a brief overview of historical and legal issues which led to the inclusive education movement, the discussion ...
Anderson, David W.
core  

Evaluasi Kebijakan Penyelenggaraan Pendidikan Inklusif Tingkat Sekolah Dasar di Kecamatan Koja Jakarta Utara (Studi pada Sdn Tugu Utara 11) [PDF]

, 2017
In Indonesia, everyone has the right to education including children with disabilities. Indonesian Government established a regulation related to this matter which is Inclusive Education Policy.
Fasha, A. F. (Azizah), Widowati, N. (Nina)   +1 more
core  

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Teacher education for inclusive education: a framework for developing collaboration for inclusion of students with support plans [PDF]

, 2019
A study was conducted to explore the impact of professional development related to the individual education plan (IEP) process on teachers’ understanding and practices in the Republic of Ireland (RoI).
King, Fiona, Ní Bhroin, Órla
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Dyadic Training of Communication Partners for Autistic Students: A Feasibility Study

Disabilities
Access to communication is a primary challenge affecting the education of Autistic students who use augmentative and alternative communication devices.
Eric J. Anderson, Emily Oehrtman, Nicholas Brown   +2 more
doaj   +1 more source