Results 61 to 70 of about 766,830 (264)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Reliability analysis for a large and complex landslide in the three gorges reservoir area (China) based on incomplete information

open access: yesGeomatics, Natural Hazards & Risk, 2019
The soil parameters for large, complex landslides are typically derived from incomplete information based on a small sample set due to budgetary constraints.
Junwei Ma   +4 more
doaj   +1 more source

Representations of Political Power Structures by Strategically Stable Game Forms: A Survey

open access: yesGames, 2017
We survey the results on representations of committees and constitutions by game forms that possess some kind of equilibrium strategies for each profile of preferences of the players.
Bezalel Peleg, Ron Holzman
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Anti-jamming transmission in a multi-channel wireless network based on incomplete information dynamic game

open access: yesDianxin kexue, 2018
Intelligent jammer can analyze the history of user’s transmission and control their own behavior,so it has brought new threats to the wireless network.In order to analyze the behavior of users and intelligent jammers in a multi-channel wireless network,a
Hengjie ZHOU   +3 more
doaj  

Filter design, fault estimation and reliable control for networked time-varying systems: a survey

open access: yesSystems Science & Control Engineering, 2017
This paper is concerned with the overview of the recent progress in filter design, fault estimation and reliable control for networked time-varying systems (NTVSs).
Jiahui Li   +4 more
doaj   +1 more source

Incomplete and Inconsistent Information Analysis Method Considering Time Factors: Dynamic Paraconsistent Soft Sets and Their Application to Decision Making

open access: yesIEEE Access, 2020
Paraconsistent soft sets can address issues involving incomplete and inconsistent information simultaneously. In this paper, paraconsistent soft sets are furtherly extended to dynamic paraconsistent soft sets by introducing time factors.
Yuanxiang Dong   +4 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

Defense decision-making method based on incomplete information stochastic game

open access: yes网络与信息安全学报, 2018
Most of the stochastic game models to select network defense strategies are composed of matrix game and Markov decision,which assumes that the defender has known the attacker's revenue.This assumption does not conform to the actual situation.The ...
Junnan YANG, Hongqi ZHANG, Chuanfu ZHANG
doaj  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

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