Results 151 to 160 of about 36,304 (249)

Diabetes management in maternally inherited diabetes and deafness (MIDD): A review and a proposed treatment algorithm

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 826-839, February 2026.
Abstract Maternally inherited diabetes and deafness (MIDD) is a mitochondrial disorder usually caused by the variant m.3243A>G in the MT‐TL1 gene. We have proposed that diabetes in MIDD arises from a combination of insulin resistance and impaired β‐cell function that is more likely to occur in the presence of high skeletal muscle heteroplasmy and ...
Ahsen Chaudhry, David M. Thompson, Jean‐Pierre Chanoine   +2 more
wiley   +1 more source

Improving cardiovascular risk stratification through the derivation and validation of an elevated triglyceride‐glucose index

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 982-993, February 2026.
Abstract Background and Aims Triglyceride‐glucose (TyG) index, is an emerging prognostic biomarker in atherosclerotic cardiovascular disease (ASCVD). Validation of its clinical value and of clinically relevant prognostic cut‐off, remains an unmet need to integrate TyG into primary prevention protocols.
Georgios Mavraganis, Georgios Georgiopoulos, Stavros Athanasopoulos, Dimitrios Terentes‐Printzios, Georgios Zervas, Christina Konstantaki, Maria Eleni Koilakou, Sofia‐Panagiota Giannakopoulou, Maria‐Angeliki Dimopoulou, Christina Chrysochoou, Konstantinos Tsioufis, Christos Pitsavos, Evangelos Liberopoulos, Konstantinos Stellos, Charalambos Vlachopoulos, Demosthenes Panagiotakos, Kimon Stamatelopoulos   +16 more
wiley   +1 more source

Molecular mechanism for pancreatic β-cell dysfunction and atherosclerosis. [PDF]

Diabetol Int
Kaneto H.
europepmc   +1 more source

Efficacy and safety of glucagon‐like peptide 1 receptor agonists across all health outcomes in type 2 diabetes: An umbrella review and evidence map of randomised controlled trials

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1136-1149, February 2026.
Abstract Aim Glucagon‐like peptide 1 receptor agonists (GLP‐1RAs) have been established as effective treatments for type 2 diabetes, offering benefits beyond glycaemic control; however, their associations across multiple health outcomes remain insufficiently assessed.
Dongjin Yeo, Yeona Jo, Jinyoung Jeong, Yi Deun Jeong, Ho Geol Woo, Yejun Son, Sunyoung Kim, Sang Youl Rhee, Dong Keon Yon   +8 more
wiley   +1 more source

Incretin Analogues for Weight Reduction in Non-Diabetic Obese: A Review of Liraglutide, Semaglutide, and Tirzepatide Beyond Glycemic Control. [PDF]

Rambam Maimonides Med J
Bonga KN, Padhan M.
europepmc   +1 more source

A metabolic comparison of GIPR agonism versus GIPR antagonism in male mice

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 1160-1167, February 2026.
Abstract Aims Targeting the glucose dependent insulinotropic polypeptide receptor (GIPR) is of growing interest for treating type 2 diabetes and obesity, though the optimal approach remains unclear. Both GIPR agonism and antagonism, respectively, incorporated into drugs like tirzepatide and maridebart cafraglutide, have paradoxically both shown ...
Iona Davies, Alexandra Turland, Hanh Duyen Tran, Carissa Wong, Olivier Cahn, Cecilia Dunsterville, Yichang Sun, Yilin Xiao, Kevin G. Murphy, Stephen R. Bloom, Ben Jones, Tricia M. M. Tan   +11 more
wiley   +1 more source

Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review. [PDF]

Int J Mol Sci
Sipos S, Jerkic M, Rotstein OD, Schweizer TA.   +3 more
europepmc   +1 more source

Heart matters: How glucose‐ and lipid‐modulating drugs remodel epicardial adipose tissue accumulation, inflammatory patterns and browning

Diabetes, Obesity and Metabolism, Volume 28, Issue 2, Page 878-894, February 2026.
Abstract Epicardial adipose tissue (EAT) is a metabolically active visceral fat depot located between the myocardium and the visceral pericardium, exerting direct paracrine and vasocrine effects on the heart and coronary vessels. Under physiological conditions, EAT supports myocardial energy metabolism and thermoregulation through fatty acid supply and
Elisabeth Heuboeck, Charnkamal Singh Bhogal, Markus Mandl   +2 more
wiley   +1 more source

Impaired Brain Incretin and Gut Hormone Expression in Human Alcohol-Related Brain Damage: Opportunities for Therapeutic Targeting. [PDF]

Biomolecules
de la Monte SM, Tong M, Carlson RI, Sutherland G.   +3 more
europepmc   +1 more source

Incretin mimetic [PDF]

, 2020
openaire   +1 more source