Results 131 to 140 of about 21,748 (299)

Impacts of Lifestyle and Microbiota‐Targeted Interventions for Overweight and Obesity on the Human Gut Microbiome: A Systematic Review

open access: yesObesity Reviews, EarlyView.
Dietary interventions showed the strongest evidence for improving microbiome composition. Probiotics and prebiotics consistently increased beneficial bacteria. Exercise and fecal microbiota transplantation had limited evidence but showed potential for microbiome modulation.
Yee Teng Lee   +6 more
wiley   +1 more source

Glucagon-like peptide-1 analogues: An overview

open access: yesIndian Journal of Endocrinology and Metabolism, 2013
Abnormalities of the incretin axis have been implicated in the pathogenesis of type 2 diabetes mellitus. Glucagon-like peptide-1 (GLP-1) and gastroinhibitory intestinal peptide constitutes >90% of all the incretin function.
Vishal Gupta
doaj   +1 more source

Understanding Impact of Anti‐Obesity Medications on Skeletal Muscle Mass Change Is Confounded by Measurement Methods

open access: yesObesity Reviews, EarlyView.
ABSTRACT Anti‐obesity medications promote greater degrees of weight loss than lifestyle interventions alone. There is an important need to understand whether loss of skeletal muscle during pharmacologically induced weight loss is clinically significant due to its essential role in health and disease.
Arden McMath, Dympna Gallagher
wiley   +1 more source

GLP‐1 Receptor Agonists for the Prevention of New‐Onset Heart Failure: A Systematic Review and Meta‐Analysis of Placebo‐Controlled Randomized Clinical Trials

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RA) improve outcomes in heart failure (HF) with preserved ejection fraction. Whether GLP‐1 RA prevent new‐onset HF in Type 2 diabetes or obesity requires further investigation. Methods We performed an updated meta‐analysis of randomized placebo‐controlled trials (RCT) of treatment ...
João Sérgio Neves   +8 more
wiley   +1 more source

Angioprotektivnoe properties lowering drugs from the group of inhibitors of dipeptidyl peptidase-4

open access: yesТерапевтический архив, 2013
Diabetes mellitus (DM) is a major health problem in all developed countries. It contributes to the development of atherosclerosis and increases the risk of cardiovascular events so blood glucose level correction is essential to preventing these ...
E V Oskola, A T Shubina, Iu A Karpov
doaj  

Nutrition Strategies for Next‐Generation Incretin Therapies: A Systematic Scoping Review of the Current Evidence

open access: yesObesity Reviews, EarlyView.
ABSTRACT Next‐generation incretin therapies, including semaglutide and tirzepatide, have transformed obesity and Type 2 diabetes management. However, evidence‐based nutritional strategies to support safe and effective use of these agents remain limited.
Marie Spreckley   +2 more
wiley   +1 more source

Problems of hypoglycemic therapy in diabetic patients with acute coronary syndrome

open access: yesМедицинский совет, 2016
Patients with diabetes mellitus (DM) are classified as "vulnerable patients" suffering from acute coronary syndrome (ACS) 2-3 times more often and have a pessimistic prognosis compared with normoglycemic patients.
L. A. Ruyatkina   +2 more
doaj   +1 more source

Multidisciplinary Therapy to Target Obesity and Its Complications in Adult Population: A Narrative Review

open access: yesObesity Reviews, EarlyView.
ABSTRACT Obesity as a chronic and multifactorial disease requires a multidisciplinary team acting together in a holistic multitarget intervention. Multidisciplinary therapy targeting obesity and its complications includes physical exercise, nutritional, and behavior counseling.
Ana Raimunda Dâmaso   +7 more
wiley   +1 more source

The Role of Insulin and Incretins in Neuroinflammation and Neurodegeneration

open access: yes, 2014
Glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotrophic polypeptide (GIP) are incretin hormones secreted from intestinal cells in response to incoming nutrients.
L. J. Spielman, A. Klegeris
semanticscholar   +1 more source

Resistance exercise breaks during prolonged sitting augment the blood flow response to a subsequent oral glucose load in sedentary adults

open access: yesExperimental Physiology, EarlyView.
Abstract Sitting‐induced impairments in postprandial blood flow are an important link between sedentary behaviour and cardiometabolic disease risk. The objective of this work was to examine the effects of resistance exercise breaks (REB) performed every 30 min during an otherwise sedentary 3‐h period on the vasodilatory response to a subsequent oral ...
Emily M. Rogers   +8 more
wiley   +1 more source

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