Results 111 to 120 of about 8,158 (292)

Incretins and their influence on the course of type 2 diabetes in patients with morbid obesity after bariatric oper

, 2012
Most researchers support the important role of incretins, particularly glucagon-like peptide-1 in improving metabolic control in patients with type 2 diabetes after bariatric operations, mostly involving shunting.

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The use of incretins and fractures - a meta-analysis on population-based real life data

, 2017
Item does not contain fulltextThe aim of the present study was to estimate the effect of incretins on fracture risk in the real-world situation by meta-analysis of the available population-based cohort data.
Henry, R.M., Vestergaard, P, Driessen, Johanna H. M., Driessen, J.H., Vestergaard, Peter, Neef, C., Harvey, Nicholas C., van den Bergh, Joop P. W.; id_orcid, Onzenoort, H. van, de Vries, F, Johanna H. M. Driessen, Driessen, J H M, Cees Neef, Henry, R M A, Nicholas C. Harvey, van Onzenoort, H, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology, van den Bergh, J, Vries, F de, Frank de Vries, Van den Bergh, Joop, Driessen, Johanna H. M.; id_orcid, Henry, Ronald M. A., Neef, C, Joop P. W. van den Bergh, de Vries, Frank; id_orcid, Peter Vestergaard, Ronald M. A. Henry, van Onzenoort, Hein, Harvey, N.C., Neef, Cees, Hein van Onzenoort, van den Bergh, Joop P. W., Harvey, N C, Bergh, J.P. van den, Vestergaard, P., de Vries, Frank, Vestergaard, P; id_orcid   +38 more
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Multivalent antibody‐based conjugates as new tools for tailored modulation of G protein–coupled receptors

British Journal of Pharmacology, EarlyView.
The G protein–coupled receptor (GPCR) superfamily consists of the most common targets of approved drugs. Targeting GPCRs offers appealing avenues for therapeutic development. Antibodies and their fragments, such as single‐domain antibodies (VHHs or nanobodies), have emerged as useful alternatives to small molecule pharmacophores as building blocks in ...
Shivani Sachdev, Ross W. Cheloha
wiley   +1 more source

The Pharmacologic Exploitation of Pleiotropic Effect of Incretins

This thesis aims to explore the various effects of incretins on the many systems of the body and how they can be utilized pharmacologically. It will investigate their use in treatment for diabetes mellitus type 2, which they were initially introduced as ...
Khan, Tazeen
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Women with COPD by biomass show different serum profile of adipokines, incretins, and peptide hormones than smokers

, 2018
Background The main causes of COPD are tobacco smoking (COPD-TS) and biomass smoke exposure (COPD-BS). COPD-TS is known to induce changes in adipokines, incretins, and peptide hormones, frequent biomarkers of inflammation; however, it is unknown if ...
Yadira Velasco-Torres, Joaquín Zúñiga-Ramos, Tonatiuh Barrientos-Gutiérrez, Martha Montaño, Carlos Ramos, Rogelio Pérez-Padilla, Mariana Camacho-Priego, Oliver Pérez-Bautista, Ivette Buendía-Roldan   +8 more
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Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Re‐thinking peripheral dysfunctions in obesity: The emerging role of sulphaceutics and sulphanutraceutics

British Journal of Pharmacology, EarlyView.
Obesity is a chronic, relapsing, multisystem disease in which cardiometabolic risk arises from excess adiposity and progressive dysfunction of peripheral organs, ultimately disrupting endocrine and metabolic crosstalk among tissues. Within this network, sulphur‐based biology, centred on hydrogen sulphide and related reactive sulphur species, has ...
Martina Smimmo, Veronica Casale, Roberta d'Emmanuele di Villa Bianca, Valentina Vellecco, Mariarosaria Bucci   +4 more
wiley   +1 more source

Abnormal release of incretins and cortisol after oral glucose in subjects with insulin-resistant myotonic dystrophy

, 2002
Objective: Although the incretins, gastric inhibitory polypeptide (GIP) and glucagon-like peptide-1 (GLP-1), as well as glucagon and cortisol, are known to influence islet function, the role of these hormones in conditions of insulin resistance and ...
Forsberg, H, Seckl, Jonathan R, Seckl, JR, Olsson, Tommy, Holst, Jens Juul, Cederquist, Kristina, Holst, JJ, Ahrén, Bo, Ahrén, Bo,, Forsberg, Hakan, Olsson, T, Johansson, Asa, Lund University., Cederquist, K, Johansson, A   +14 more
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From narratives to numbers and back: Assessing the psychosocial aspects of diabetes in the era of high technology with emerging qualitative and quantitative methodologies

Diabetic Medicine, EarlyView.
Abstract Aims Rapid changes in diabetes therapy combined with limitations of traditional methodological approaches challenge the field of psychosocial research to adequately capture the experiences of people with diabetes. This narrative review provides an overview of emerging qualitative and quantitative approaches that can advance the study of ...
Dominic Ehrmann, Eloise Litterbach, Sonya Deschenes, Rita Forde, Norbert Hermanns, Maaike Horsselenberg, Mandy Jansen, Amy McInerney, Eimear Morrissey, Andreas Schmitt, Uffe Søholm, Giesje Nefs   +11 more
wiley   +1 more source

Incretins and diabetes mellitus type 2 - from pathophysiology to therapeutic treatment [PDF]

, 2014
Moderni terapijski pristup liječenju šećerne bolesti tipa 2 usmjeren je na povećanje razine inkretinskih hormona u cirkulaciji. Inkretini su endogeni regulatorni peptidi koje izlučuju stanice crijeva i koji potiču otpuštanje inzulina, inhibiraju ...
Ranđelović, Karla
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