Results 11 to 20 of about 1,900 (132)
Characterization of Liquid Formulations for Enhanced Buccal Permeation: Exploring Key Attributes [PDF]
BiomedicinesBackground: Buccal administration offers direct access to systemic circulation, improving drug bioavailability when compared with the conventional oral route. This advantage depends on the formulation’s ability to remain in contact with the buccal mucosa.
Ariana Sena +5 more
doaj +2 more sources
Etodolac Single Dose Metabolic Profile Elucidation: Pharmacokinetics and Adverse Events in Healthy Volunteers [PDF]
PharmaceuticalsBackground/Objectives: This study investigates the metabolic profile of a single dose of etodolac in healthy volunteers, focusing on pharmacokinetics, clinical parameters, and metabolomic variations to identify biomarkers and pathways linked to drug ...
Karen Sánchez-Luquez +9 more
doaj +2 more sources
Pharmacometabolomics Approach to Explore Pharmacokinetic Variation and Clinical Characteristics of a Single Dose of Desvenlafaxine in Healthy Volunteers [PDF]
PharmaceuticsThis study investigated the effects of a single dose of desvenlafaxine via oral administration on the pharmacokinetic parameters and clinical and laboratory characteristics in healthy volunteers using a pharmacometabolomics approach. In order to optimize
Anne Michelli Reis Silveira +10 more
doaj +2 more sources
Amphiphile-Assisted Synthesis of Ruthenium Nanoparticles for Controlled Release and Enhanced Antibacterial Activity. [PDF]
Small MethodsA novel synthesis of Ruthenium nanoparticles (RuNPs) based on amphiphiles and Ru(III) complexes as antibacterial agents with controlled release properties has been developed. Post‐synthesis modification of the RuNPs with PEG molecular staples enables controlled Ru release, reducing the burst effect.
Gimeno-Ferrero R +5 more
europepmc +2 more sources
Pharmaceutics, 2023 Analytical method validation ensures that a method provides trustworthy information about a particular sample when applied in accordance with the predefined protocol. According to regulatory standards, the rheological characteristics of topically applied
Lucas Chiarentin +3 more
doaj +1 more source
Influência do marketing farmacêutico nas prescrições médicas: uma revisão da literatura
Jornal de Assistência Farmacêutica e Farmacoeconomia, 2022 Introdução: A indústria farmacêutica faz parte de um mercado competitivo e de investimentos grandes em pesquisa, desenvolvimento, produção e marketing de produtos farmacêuticos.
Gabriel Rodrigues Martins de Freitas +2 more
doaj +1 more source
Vigilância Sanitária em Debate: Sociedade, Ciência & Tecnologia, 2023 Introdução: O novo marco regulatório de insumos farmacêuticos ativos compreende três resoluções editadas pela Agência Nacional de Vigilância Sanitária em 2020, RDC nº 359, RDC nº 361 e RDC nº 672, inaugurando novas abordagens para regularização do ...
Soraya Mileti da Costa +2 more
doaj +1 more source
Relación de la industria farmacéutica con los médicos residentes de la República Dominicana
Ciencia y Salud, 2020 Introducción: las relaciones médicas con la industria farmacéutica son cada vez más complejas y los desafíos éticos que plantea son reales. Objetivo: conocer la relación que existe entre la industria farmacéutica con los médicos residentes del país y ...
Ricardo Elías Melgen +1 more
doaj +1 more source
Vigilância Sanitária em Debate, 2015 O presente estudo teve por objetivo investigar e avaliar a potencial contribuição que a obrigatoriedade do registro de Insumos Farmacêuticos Ativos (IFAs) teve no estabelecimento da isonomia regulatória entre o fabricante de IFA no Brasil e o fabricante internacional e a efetividade que essa isonomia teve no restabelecimento da produção local desses ...
Diva Barrio Arrepia +2 more
openaire +5 more sources
Acta Scientiarum: Technology, 2011 This paper aimed to characterize and qualify a secondary standard of diclofenac sodium as a reference standard in the quality control of medicines.
Paulo Roberto Stoef +4 more
doaj +1 more source