Identification and characterization of a novel cathinone derivative 1-(2,3dihydro-1H-inden-5-yl)-2-phenyl-2-(pyrrolidin-1-yl)-ethanone seized by customs in Jersey [PDF]
, 2015 A suspicious white powder labeled “idanyl-biphenyl-amninone,” which was seized by customs officials at the "channel island" of Jersey, UK, was brought to our laboratory for identification and characterization of its structure.
Bijlsma, Lubertus +6 more
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MolbankIndazoles are a very important group of nitrogen-containing heterocycles with a wide range of biological and medicinal applications. These properties make them highly attractive for drug development, particularly when combined with sulfonamides to ...
Nassima Saghdani +3 more
doaj +1 more source
3-Bromo-6-nitro-1-(prop-2-en-1-yl)-1H-indazole
IUCrData, 2018 The asymmetric unit of the title compound, C10H8BrN3O2, contains two independent molecules differing primarily in the orientations of the allyl substituents [N—C—C=C torsion angles = −125.4 (16) and 116.0 (16)°].
Mohamed Mokhtar Mohamed Abdelahi +4 more
doaj +1 more source
Monitoring new psychoactive substances use through wastewater analysis: current situation, challenges and limitations [PDF]
, 2019 New psychoactive substances (NPSs) are compounds that produce similar effects to those induced by illicit drugs (IDs), such as cocaine, cannabis, and amphetamines, but are not strictly regulated by international conventions.
Bijlsma, Lubertus +3 more
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Tonic and phasic nitric oxide signals in hippocampal long-term potentiation [PDF]
, 2006 Nitric oxide ( NO) participates in long-term potentiation (LTP) and other forms of synaptic plasticity in many different brain areas but where it comes from and how it acts remain controversial.
Garthwaite, J, Hopper, RA
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Temperoammonic stimulation depotentiates Schaffer collateral LTP via p38 MAPK downstream of adenosine A1 receptors [PDF]
, 2019 We previously found that low-frequency stimulation of direct temperoammonic (TA) inputs to hippocampal area CA1 depotentiates previously established long-term potentiation in the Schaffer collateral (SC) pathway through complex signaling involving ...
Izumi, Yukitoshi, Zorumski, Charles F
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Photo- and electro-chemical strategies for indazole synthesis
Tetrahedron ChemThe indazole core is prevalently found in the structures of bioactive molecules, demonstrating promising potential in medicinal chemistry and drug discovery, which therefore has attracted sustained attention from the synthetic community.
Binbin Huang
doaj +1 more source
Technical report on 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3-carboxamide (CUMYL-4CN-BINACA). Annex 1 to the Risk Assessment Report on 1-(4-cyanobutyl)-N-(2-phenylpropan-2-yl)-1H-indazole-3- carboxamide (CUMYL-4CN-BINACA). [PDF]
In accordance with Article 6 of Council Decision 2005/387/JHA on the information exchange, risk assessment and control of new psychoactive ...
Almeida, A +10 more
core
New Syntheses of Indazole and 2-Substituted Indazoles. [PDF]
Acta Chemica Scandinavica, 1975 Jan M. Bakke +2 more
openaire +1 more source
Investigation of the binding of cis/trans-[MCl4(1H-indazole)(NO)]- (M = Ru, Os) complexes to human serum albumin [PDF]
, 2016 Arion Vladimir B. +6 more
core +1 more source