Results 71 to 80 of about 7,519 (213)
Acta Crystallographica Section E: Crystallographic Communications, 2016 The title compound, C13H19N3OS, is a new thiazolidin-4-one derivative prepared and isolated as the pure (3aS,6R)-diastereisomer from (R)-thiosemicarbazone pulegone. It crystallized with two independent molecules (A and B) in the asymmetric unit.
Abdellah N'ait Ousidi +5 more
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Investigations into the synthesis of Indazole [PDF]
, 1951 These investigations were undertaken in order to prepare a suitable quantity of pure indazole for further research by other student. A secondary and equally important purpose of the work was to study the products of the reaction carried out and their ...
Rzeszotarski, Albin Joseph
core
2-(4-Methylphenyl)-2H-indazole
, 2010 The title compound, C14H12N2, was synthesized by the reaction of 4-methyl-N-(2-nitrobenzyl)aniline with tin(II) chloride dihydrate in ethanol at 313 K.
Xingqin Zhou +2 more
core +1 more source
Synthesis and biological evaluation of new indazole derivatives
, 2010 New N-methyl and N-ethyl substitutions in the indazole nucleus are reported by reacting 3-(2-aminobenzamido)indazole and the appropriate trimethyl/triethyl orthobenzoate. Single crystal X-ray analysis confirms the N-ethylation position for the 3-(1-ethyl-
Fiorella Meneghetti +29 more
core +2 more sources
Acta Crystallographica Section E: Crystallographic Communications, 2015 In the title compound, C22H18N2O4, the three fused rings of the pyrazolophthalazine moiety are coplanar (r.m.s. deviation = 0.027 Å). The cyclohexene ring fused to the pyrazolidine ring, so forming the indazolophthalazine unit, has a half-chair ...
Abdelmalek Bouraiou +4 more
doaj +1 more source
An Alternative Indazole Synthesis for Merestinib
, 2018 A new synthesis of a key indazole-containing building block for the MET kinase inhibitor merestinib was designed and demonstrated. Crucial to the successful construction of the challenging indazole is an SNAr reaction, which forges the heterocyclic ring.
Todd D. Maloney (1950847) +6 more
core +1 more source
Photo- and electro-chemical strategies for indazole synthesis
Tetrahedron ChemThe indazole core is prevalently found in the structures of bioactive molecules, demonstrating promising potential in medicinal chemistry and drug discovery, which therefore has attracted sustained attention from the synthetic community.
Binbin Huang
doaj +1 more source
New azo disperse dyes containing cyclohexanone ring for dyeing polyester and nylon fabrics
Macedonian Journal of Chemistry and Chemical Engineering, 2010 Condensation of 2,4-diacarboethoxy-5-hydroxy-3-(4-methoxyphenyl)-5-methyl cyclohexanone (1) with equimolar amounts of hydrazine hydrate and phenyl hydrazine afforded the corresponding 2H-indazole-5-carboxylates 2a and 2b, respectively.
Hatem E. Gaffer +3 more
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Design, Synthesis and Anticandidal Evaluation of Indazole and Pyrazole Derivatives
, 2021 Candidiasis, caused by yeasts of the genus Candida, is the second cause of superficial and mucosal infections and the fourth cause of bloodstream infections.
Lilián Yépez-Mulia +10 more
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Indazole: Photoleitfähigkeit und Oxidationspotentiale
CHIMIA, 1988 In sensitized electrophotographic layers, excellent charge transport properties are exhibited by 2-(p-aminophenyl)indazoles (1). Corresponding 2-aminoindazoles (2) are ineffective.
Bernhard Albert +2 more
doaj +1 more source